This document discusses Karl Fischer titration, which is a method for determining the water content in a sample. It involves titrating the sample with a Karl Fischer reagent, which contains iodine, sulfur dioxide, and an alcohol solvent. There are two main types of Karl Fischer titration: coulometric titration, where iodine is generated in the titration cell, and volumetric titration, where a solution with a known iodine concentration is used as the titrant. The endpoint is detected electrochemically. Karl Fischer titration is used in various industries to measure water content in products like oils, plastics, gases, cosmetics, pharmaceuticals, and food. A limitation is that the

1. Faruk Hossen
ID:20151109005
Karl Fischer Titration

2. KF Introduction
Reagents
KF Instruments
Types
Endpoint indication
Applications
Limitations
TOPICS

3. INTRODUCTION

4. Basic ingredients of KF reagents
* Iodine
* Sulphur dioxide
* Buffer
* Solvent
I2
SO2
Imidazole
Methanol

5. *Drying tube
*Cathode chamber
*Sample injection cap
*Detection electrode
*Electrode analysis
*Rotor
*Drain cook
*Anode chamber

6. log K
pH

7. KF titration methods
Coulometric KF titration
Iodine is generated in titration
cell (anodic oxidation)
Volumetric KF titration
Working medium & titrant

8. The main compartment of the titration cell
contains the anode solution plus the analyte.
1.alcohol (ROH),
2.a base (B),
3. SO2
4. I2.
A typical alcohol that may be used
is methanol or diethylene glycol monoethyl
ether, and a common base is imidazole.

9. The volumetric titration is based on the same
principles as the coulometric titration except that
the anode solution above now is used as the titrant
solution.
The titrant:
1. an alcohol (ROH),
2. base (B),
3. SO2
4. a known concentration of I2.
5. Pyridine has been used as the base in this case.

10. Endpoint indication

11. • in technical products
(oil, plastics and gases)
• in cosmetic products
• in pharmaceutical products
• in food industry

12. • The major disadvantage with solids is that
the water has to be accessible.
• Easily brought into methanol solution.
• KF is selective for water