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ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
Raymond G Buick
Paediatric Surgeon
Birmingham
Length: approx 55 minutes
ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
Lecture given to
Paediatric Surgery for Specialist Trainees
Raymond G Buick
Paediatric Surgeon
Birmingham
February 2009
ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
•Pathophysiology
•Causes of abdominal pain
•Diagnosis of acute abdominal pain
•Acute appendicitis
•A few rare causes of acute abdominal pain
ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
pathophysiology
Clinically, abdominal pain falls into three categories:
• visceral (splanchnic) pain,
• parietal (somatic) pain,
• referred pain.
Clinically, abdominal pain falls into three categories:
• visceral (splanchnic) pain---visceral pain fibers
are bilateral and unmyelinated and enter the spinal
cord at multiple levels,
visceral pain usually is dull, poorly localized, and felt
in the midline
• parietal (somatic) pain,
• referred pain.
Clinically, abdominal pain falls into three categories:
• visceral (splanchnic) pain,
• parietal (somatic) pain--- Parietal pain arises from
noxious stimulation of the parietal peritoneum. Pain
resulting from ischemia, inflammation, or stretching of
the parietal peritoneum is transmitted through
myelinated afferent fibers to specific dorsal root
ganglia on the same side and at the same dermatomal
level as the origin of the pain. Parietal pain usually is
sharp, intense, discrete, and localized, and coughing or
movement can aggravate it.
• referred pain.
Clinically, abdominal pain falls into three categories:
• visceral (splanchnic) pain,
• parietal (somatic) pain,
• referred pain-- Referred pain has many of the
characteristics of parietal pain but is felt in remote
areas supplied by the same dermatome as the
diseased organ. It results from shared central
pathways for afferent neurons from different sites. A
classic example is a patient with pneumonia who
presents with abdominal pain because the T9
dermatome distribution is shared by the lung and the
abdomen.
ABDOMINAL PAIN
• Causes of ACUTE ABDOMINAL PAIN
Causes of Acute Abdominal Pain in Children
Gastrointestinal causes
Gastroenteritis
Appendicitis
Mesenteric lymphadenitis
Constipation
Flatulence
Abdominal trauma
Intestinal obstruction
Peritonitis
Food poisoning
Peptic ulcer
Meckel's diverticulum
Inflammatory bowel disease
Lactose intolerance
Hernia
Liver, spleen, and biliary tract
disorders
Hepatitis
Cholecystitis
Cholelithiasis
Splenic infarction
Rupture of the spleen
Pancreatitis
Genitourinary causes
Urinary tract infection
Urinary calculi
Dysmenorrhoea
Mittelschmerz
Pelvic inflammatory disease
Threatened abortion
Ectopic pregnancy
Ovarian/testicular torsion
Endometriosis
Hematocolpos
Metabolic disorders
Diabetic ketoacidosis
Hypoglycaemia
Porphyria
Acute adrenal insufficiency
Hematologic disorders
Sickle cell anemia
Henoch-Schönlein purpura
Haemolytic uremic syndrome
Drugs and toxins
Erythromycin
Salicylates
Lead poisoning
Venoms
Iron overdose
Soap ingestion
Pulmonary causes
Pneumonia
Diaphragmatic pleurisy
Miscellaneous
Infantile colic
Functional pain
Pharyngitis Angioneurotic oedema
Familial Mediterranean fever
Floating Rib Syndrome
Adapted from : Acute Abdominal Pain in Children
ALEXANDER K.C. LEUNG, DAVID L. SIGALET,
American Family Physician® >
Vol. 67/No. 11 (June 1, 2003)
ABDOMINAL PAIN
• Causes of ACUTE ABDOMINAL PAIN
• AGE
• SEX
Differential Diagnosis of Acute
Abdominal Pain by Predominant
Age
Birth to one year Two to five years Six to 11 years 12 to 18 years
Infantile colic Gastroenteritis Gastroenteritis Appendicitis
Gastroenteritis Appendicitis Appendicitis Gastroenteritis
Constipation Constipation Constipation Constipation
Urinary tract infection Urinary tract infection Functional pain Dysmenorrhoea
Intussusception Intussusception Urinary tract infection Mittelschmerz
Volvulus Volvulus Trauma Pelvic inflammatory
disease
Incarcerated hernia Trauma Pharyngitis Threatened abortion
Hirschsprung's disease Pharyngitis Pneumonia Ectopic pregnancy
Trauma Sickle cell crisis Sickle cell crisis Ovarian/testicular torsion
Henoch-Schönlein purpura Henoch-Schönlein purpura
Mesenteric lymphadenitis Mesenteric lymphadenitis
Adapted from : Acute Abdominal Pain in Children
ALEXANDER K.C. LEUNG, DAVID L. SIGALET, American Family Physician® > Vol. 67/No. 11 (June 1, 2003)
ABDOMINAL PAIN
Causes of ACUTE ABDOMINAL PAIN in very
young children
• Neonates – acute abdomen
• Intestinal volvulus
• Incarcerated inguinal hernia
• Hirschsprung's disease
• Intussusception
• Trauma – non-accidental
Causes of Abdominal Pain in Children
  Emergencies/life-threatening Other causes
Medical causes Diabetic Ketoacidosis Gastroenteritis (bacteria or viruses)
Inflammatory bowel disease Constipation
Acute adrenal failure Flatulence
  Mesenteric lymphadenitis
  Peptic ulcer disease
  Urinary tract infection
  Ureteric calculi
  Hepatitis
  Cholecystitis
  Pancreatitis
  Sickle cell anaemia/crises
  Henoch Schonlein purpura
Surgical causes Appendicitis  
Bowel obstruction (e.g. 
intussusception, volvulus)
Trauma
Incarcerated hernia
Peritonitis
Testicular torsion
Gynaecological causes   Dysmenorrhoea
Mittelschmerz
Pelvic inflammatory disease
Endometriosis
Obstetric causes Ectopic pregnancy  
Ovarian cyst rupture/torsion
Abortion
Drugs/Toxins Paracetamol overdose Soap ingestion
Iron overdose Erythromycin
Venoms  
Referred pain   Pneumonia
Rare causes   Angioneurotic oedema
Familial Mediterranean fever
Unknown aetiology   Infantile colic
Functional bowel disease
ADMISSIONS
363
OPERATIONS
125
35%
OTHER SURGICAL
DIAGNOSES OR NEGATIVE
24
6%
MEDICAL
129
35%
APPENDICITIS
106
29%
NON-SPECIFIC
ABDOMINAL PAIN
108
30%
OBSERVED
237
65%
Admissions with Abdominal Pain to a District General Hospital in one year
HOME
CHEMIST
NHS DIRECT
GP
Admissions with Abdominal Pain to a Paediatric Surgical Unit in one year
• The most common medical cause is
gastroenteritis
• The most common surgical cause is
appendicitis.
ACUTE ABDOMINAL PAIN
Pain & vomiting
• In the acute surgical abdomen, pain generally
precedes vomiting, while the reverse is true in
medical conditions.
• The most common medical cause is
gastroenteritis – Viruses
rotavirus,
Norwalk virus,
adenovirus,
Enterovirus
Bacteria
Escherichia coli,
Yersinia,
Campylobacter,
Salmonella,
Shigella.
ABDOMINAL PAIN
Causes of Acute Abdominal Pain in Children
Gastrointestinal causes
Gastroenteritis
Appendicitis
Mesenteric lymphadenitis
Constipation
Flatulence
Abdominal trauma
Intestinal obstruction
Peritonitis
Food poisoning
Peptic ulcer
Meckel's diverticulum
Inflammatory bowel disease
Lactose intolerance
Hernia
Liver, spleen, and biliary tract
disorders
Hepatitis
Cholecystitis
Cholelithiasis
Splenic infarction
Rupture of the spleen
Pancreatitis
Genitourinary causes
Urinary tract infection
Urinary calculi
Dysmenorrhoea
Mittelschmerz
Pelvic inflammatory disease
Threatened abortion
Ectopic pregnancy
Ovarian/testicular torsion
Endometriosis
Hematocolpos
Metabolic disorders
Diabetic ketoacidosis
Hypoglycaemia
Porphyria
Acute adrenal insufficiency
Hematologic disorders
Sickle cell anemia
Henoch-Schönlein purpura
Haemolytic uremic syndrome
Drugs and toxins
Erythromycin
Salicylates
Lead poisoning
Venoms
Iron overdose
Soap ingestion
Pulmonary causes
Pneumonia
Diaphragmatic pleurisy
Miscellaneous
Infantile colic
Functional pain
Pharyngitis Angioneurotic oedema
Familial Mediterranean fever
Floating Rib Syndrome
Adapted from : Acute Abdominal Pain in Children
ALEXANDER K.C. LEUNG, DAVID L. SIGALET,
American Family Physician® > Vol. 67/No. 11 (June 1,
2003)
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Up to 20% of infants
First 6 months
Scream
Draw knees up
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Over diagnosed
Pain – Visceral / LIF
Acute – organic cause
Chronic – functional cause
Diagnosis of last resort
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Adenovirus
Preceding upper resp infectionMay
Other lymphadenopathy
mimic appendicitis
Pain more diffuse
Higher temperature
Shifting tenderness
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
ACCIDENTAL
NON-ACCIDENTAL
Parents may conceal information
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Includes
•Malrotation
•Volvulus
•Intussusception
•Incarcerated hernia
•adhesions
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Includes
•Malrotation
•Volvulus
•Intussusception
•Incarcerated hernia
•Adhesions – ACQUIRED
--
CONGENITAL
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Chlamydia
Neisseria
infection and inflammation of the upper female genital tract, uterus, fallopian
tubes and ovaries.
infection in the vagina & cervix passing to the internal reproductive organs.
Age 15 to 24
2% female population
20% recurrent
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Chlamydia
Neisseria
AND Pregnancy
History may be concealed
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Chlamydia
Neisseria
AND Pregnancy
History may be concealed
PregnancyPregnancy
10% occur in 13 to 15 (7.8 per 1000)10% occur in 13 to 15 (7.8 per 1000)
52% occur in 13 to 17 (41 per 1000)52% occur in 13 to 17 (41 per 1000)
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
NICE Guidelines -August 2007
www.nice.org.uk/Guidance/CG54/NiceGuidance/pdf/English
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
NICE Guidelines -August 2007
e
Symptoms and
signs
Most common Least Common
Preverbal Fever Abdominal pain
Loin tenderness
Vomiting
Poor feeding
Lethargy
Irritability
Haematuria
Offensive urine
Failure to thrive
Verbal Frequency
Dysuria
Dysfunctional voiding
Changes to continence
Abdominal pain
Loin tenderness
Fever
Malaise
Vomiting
Haematuria
Offensive urine
Cloudy urine
• Infantile colic
• Constipation
• Mesenteric adenitis
• Abdominal trauma
• Intestinal obstruction
• Pelvic inflammatory disease
• Urinary Tract Infection
• Meckel’s Diverticulum
ABDOMINAL PAIN
Meckel’s Diverticulum
Meckel’s Diverticulum
• Meckel's diverticulum,
• congenital
• remnant of the vitelointestinal duct (omphalomesenteric duct)
• 2 feet (from the ileocecal valve)
• 2 inches (in length)
• 2% (of the population) have it
• 2% are symptomatic
• 2 is the most common age at clinical presentation
• 2:1 male:female
• 2 types of common ectopic tissue (gastric and pancreatic)
• first described by Fabricius Hildanus C16first described by Fabricius Hildanus C16
• named after Johann Friedrich Meckelnamed after Johann Friedrich Meckel
who described the embryological originwho described the embryological origin
of this type of diverticulum in 1809of this type of diverticulum in 1809
ABDOMINAL PAIN
• diagnosis
ABDOMINAL PAIN
• History
• A challenge in young children
• poor sense of timing and location
ABDOMINAL PAIN
• History
• PAIN Location
• Onset
• Character
• Change of location or character
• Severity
• Radiation
• Precipitating/relieving factors
ABDOMINAL PAIN
• History
• VOMITING character
• frequency
• content bile / blood
• BOWELS frequency
• consistency
• blood
• URINARY frequency/dysuria/polyuria/urgency/odour/colour
• RESPIRATORYcough/SOB/chest pain
• GENERAL temperature/headache/joint pains-swelling/rash/sore throat
• GYNAE menstruation/LMP/sexual activity/contraception/vaginal
discharge/?midcycle
• PAST MEDICAL HISTORY / DRUG HISTORY / FAMILY HISTORY
ABDOMINAL PAIN
• Examination
• GENERAL APPEARANCE
• GENERAL – ENT
• – Chest
• ABDOMINAL Breathing pattern
• distension
• Point to pain
• Maximum tenderness
• Muscle guarding
• Rebound tenderness
• bowel sounds
• groin / testes / introitus
• Rectal Examination
ABDOMINAL PAIN
• Investigations
• Tailored to symptoms and signs
• CONSIDER Full Blood Picture
• Differential White Cell Count
• Urinalysis
• CRP
• Pregnancy Test
•
• Abdominal X-Ray
• Chest x-Ray
• Ultrasound
• CT
ABDOMINAL PAIN
Active Observation
ABDOMINAL PAIN
“repeated physical examination by the same
physician often is useful”
ABDOMINAL PAIN
repeated physical examination is
MANDATORY
by the same physician is
BENIFICIAL
ABDOMINAL PAIN
Active Observation
ABDOMINAL PAIN
RECORDED
Active Observation
ABDOMINAL PAIN
Recorded
Active
Observation
• in most instances, abdominal pain can be
diagnosed through the history and physical
examination.
‘THE PAIN’ in ABDOMINAL PAIN
• Use analgesia as required - it does not affect
diagnostic accuracy
Patient UK at
www.patient.co.uk/showdoc/40000523/
‘THE PAIN’ in ABDOMINAL PAIN
• Traditionally, the use of analgesics is discouraged in patients with abdominal pain for fear of interfering
with accurate evaluation and diagnosis.
• However, several prospective, randomized studies have shown that judicious use of analgesics actually
may enhance diagnostic accuracy by permitting detailed examination of a more cooperative patient.
APPENDICITIS
APPENDICITIS
• Age
The approach to common abdominal diagnosis in infants and children
Irish M S et al
Pediatric Clin North Am. 1998 Aug: 45(4): 729-72
% PERFORATED % NORMAL
Age <= 8 years 33 13
Age > 8 years 18 11
Male 22 8
Female 18 17
Age in Years 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Acute
appendicitis
without
perforation 2 8 17 30 33 17 43 57 97 111 137 168 144 163 104 91178
Acute
appendicitis
with
perforation 2 3 10 23 20 16 16 23 27 25 16 16 12 22 8 18 42
Total
number of
patients 4 11 27 53 53 33 59 80 124 136 153 184 156 185 112 109220
Percentage
perforated 50 27 37 46 38 48 27 27 22 18 10 9 8 12 7 17 19
APPENDICITIS
• What causes appendicitis
APPENDICITIS
• Types of Appendicitis
pathogenesis
primary obstruction of the lumen of appendix
filled with mucus and swells.
increasing pressure within the lumen
Pressure on the wall of the appendix
resulting in thrombosis & occlusion of blood vessels
Inflammation of appendix
Pus may form within the appendix (suppuration)
stasis of lymph flow - leads to ischaemia and necrosis (gangrene)
Bacteria begin to leak out through appendix walls
Pus forms within and around the appendix
Perforation of appendix - peritonitis / abscess
Septicaemia - death
}Appendix Mass
APPENDICITIS
• Types of Appendicitis
– Acute
– Perforated
APPENDICITIS
• Types of Appendicitis
– Acute
• Acute inflammatory appendicitis
• Acute Suppurative appendicitis
– Perforated (complicated)
• Perforated
• Gangrenous
APPENDICITIS
• Types of Appendicitis
– Acute
• Acute inflammatory appendicitis
• Acute Suppurative appendicitis
– Perforated (complicated)
• Perforated
• Gangrenous
• Normal
• (Registrar’s Appendicitis)
APPENDICITIS
• Types of Appendicitis
– Acute
• Acute inflammatory appendicitis
• Acute Suppurative appendicitis
– Perforated (complicated)
• Perforated
• Gangrenous
• Normal
Appendix Mass
Appendix Abscess
Clinical Features - Symptoms
Clinical Features - Symptoms
• Pain – Central
» Vague
» Crampy
» Wants to move around
– Moves to Right Iliac Fossa
» Acute
» Sharp / constant
» Wants to lie still
Anorexia
Nausia
Vomiting
Mild Pyrexia
Halitosis
Change in bowel habit – diarrhoea
-- constipation
Urinary Symptoms
LOCALISED
Clinical Features - Signs
Clinical Features - Signs
• Localised Tenderness
• Muscle Guarding Tachycardia
Flushed
Circum-oral pallor
Rectal Examination ?
Rovsing’s Sign
Psoas sign
Obturator sign
Caecal Gurgle
Clinical Features - Signs
• Localised Tenderness
• Muscle Guarding Tachycardia
Flushed
Circum-oral pallor
Rectal Examination ?
Rovsing’s Sign
Niels Thorkild Rovsing Danish surgeon 1907,
Psoas sign
Obturator sign
Caecal Gurgle
Clinical Features - Signs
• Localised Tenderness
• Muscle Guarding Tachycardia
Flushed
Circum-oral pallor
Rectal Examination ?
Rovsing’s Sign
Psoas sign
Obturator sign
Caecal Gurgle
Action:-
Hip flexion
Pain:-Pain:-
Hip ExtensionHip Extension
Clinical Features - Signs
• Localised Tenderness
• Muscle Guarding Tachycardia
Flushed
Circum-oral pallor
Rectal Examination ?
Rovsing’s Sign
Psoas sign
Obturator sign
Caecal Gurgle
Action:-
Abducts
Lat Rotates
Pain:-Pain:-
Hip AdductionHip Adduction
Internal RotationInternal Rotation
Clinical Features - Signs
• Localised Tenderness
• Muscle Guarding Tachycardia
Flushed
Circum-oral pallor
Rectal Examination ?
Rovsing’s Sign
Psoas sign
Obturator sign
Caecal Gurgle
Clinical Features - Signs
• Localised Tenderness
• Localised Guarding
Anatomical positions of appendix
• Retrocaecal – poor localising signs
• Retroileal – diarrhoea
• Pelvic – diarrhoea / Bladder
CLASSICAL CARDINAL FEATURES
• Localised Pain
• Localised Tenderness
• Muscle Guarding
• (Rebound Tenderness)
McBurney’s Point
Charles McBurney U.S. surgeon, 1845–1913
Investigations
• Blood Test
– Sickle
– Neutrophil leucocytosis
– Lymphopenia
– CRP
Investigations
• Radiology
– Abdominal film
• Obstruction
• faecolith
• Soft tissue mass
• Loaded colon
– Ultrasound
• Gynaecological
• Abscess/mass/thick bowel loops
• stones
APPENDICITIS
• Preparation for theatre
– Analgesics
– Fluids
– Antibiotics
– Consent
APPENDICITIS
• In theatre
– EUA
• Open or Laparoscopic ?
APPENDICITIS
• In theatre
– EUA
• Open or Laparoscopic ?
• What if it is perforated ?
APPENDICITIS
• In theatre
– EUA
• Open or Laparoscopic ?
• What if it is Crohn’s ?
APPENDICITIS
• In theatre
– EUA
• Open or Laparoscopic ?
• What if it is normal ?
A few less common causes ofA few less common causes of
ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
Henoch-Schönlein purpura
• systemic vasculitis
• deposition of immune complexes containing
the antibody IgA in the skin and kidney
• occurs mainly in young children.
Henoch-Schönlein purpura
• self-limiting
• no treatment - symptom control,
• in a third of cases disease may relapse
-irreversible kidney damage in about 1% of
cases
• Cause unknown, post viral and bacterial
infections, / adverse drug reactions
12th
Rib Syndrome
• Floating Rib
• Slipping Rib
• Rib Dysfunction

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Acute Abdominal Pain in Children

  • 1. ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN Raymond G Buick Paediatric Surgeon Birmingham Length: approx 55 minutes
  • 2. ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN Lecture given to Paediatric Surgery for Specialist Trainees Raymond G Buick Paediatric Surgeon Birmingham February 2009
  • 3. ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN •Pathophysiology •Causes of abdominal pain •Diagnosis of acute abdominal pain •Acute appendicitis •A few rare causes of acute abdominal pain ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
  • 4. pathophysiology Clinically, abdominal pain falls into three categories: • visceral (splanchnic) pain, • parietal (somatic) pain, • referred pain.
  • 5. Clinically, abdominal pain falls into three categories: • visceral (splanchnic) pain---visceral pain fibers are bilateral and unmyelinated and enter the spinal cord at multiple levels, visceral pain usually is dull, poorly localized, and felt in the midline • parietal (somatic) pain, • referred pain.
  • 6. Clinically, abdominal pain falls into three categories: • visceral (splanchnic) pain, • parietal (somatic) pain--- Parietal pain arises from noxious stimulation of the parietal peritoneum. Pain resulting from ischemia, inflammation, or stretching of the parietal peritoneum is transmitted through myelinated afferent fibers to specific dorsal root ganglia on the same side and at the same dermatomal level as the origin of the pain. Parietal pain usually is sharp, intense, discrete, and localized, and coughing or movement can aggravate it. • referred pain.
  • 7. Clinically, abdominal pain falls into three categories: • visceral (splanchnic) pain, • parietal (somatic) pain, • referred pain-- Referred pain has many of the characteristics of parietal pain but is felt in remote areas supplied by the same dermatome as the diseased organ. It results from shared central pathways for afferent neurons from different sites. A classic example is a patient with pneumonia who presents with abdominal pain because the T9 dermatome distribution is shared by the lung and the abdomen.
  • 8. ABDOMINAL PAIN • Causes of ACUTE ABDOMINAL PAIN
  • 9. Causes of Acute Abdominal Pain in Children Gastrointestinal causes Gastroenteritis Appendicitis Mesenteric lymphadenitis Constipation Flatulence Abdominal trauma Intestinal obstruction Peritonitis Food poisoning Peptic ulcer Meckel's diverticulum Inflammatory bowel disease Lactose intolerance Hernia Liver, spleen, and biliary tract disorders Hepatitis Cholecystitis Cholelithiasis Splenic infarction Rupture of the spleen Pancreatitis Genitourinary causes Urinary tract infection Urinary calculi Dysmenorrhoea Mittelschmerz Pelvic inflammatory disease Threatened abortion Ectopic pregnancy Ovarian/testicular torsion Endometriosis Hematocolpos Metabolic disorders Diabetic ketoacidosis Hypoglycaemia Porphyria Acute adrenal insufficiency Hematologic disorders Sickle cell anemia Henoch-Schönlein purpura Haemolytic uremic syndrome Drugs and toxins Erythromycin Salicylates Lead poisoning Venoms Iron overdose Soap ingestion Pulmonary causes Pneumonia Diaphragmatic pleurisy Miscellaneous Infantile colic Functional pain Pharyngitis Angioneurotic oedema Familial Mediterranean fever Floating Rib Syndrome Adapted from : Acute Abdominal Pain in Children ALEXANDER K.C. LEUNG, DAVID L. SIGALET, American Family Physician® > Vol. 67/No. 11 (June 1, 2003)
  • 10. ABDOMINAL PAIN • Causes of ACUTE ABDOMINAL PAIN • AGE • SEX
  • 11. Differential Diagnosis of Acute Abdominal Pain by Predominant Age Birth to one year Two to five years Six to 11 years 12 to 18 years Infantile colic Gastroenteritis Gastroenteritis Appendicitis Gastroenteritis Appendicitis Appendicitis Gastroenteritis Constipation Constipation Constipation Constipation Urinary tract infection Urinary tract infection Functional pain Dysmenorrhoea Intussusception Intussusception Urinary tract infection Mittelschmerz Volvulus Volvulus Trauma Pelvic inflammatory disease Incarcerated hernia Trauma Pharyngitis Threatened abortion Hirschsprung's disease Pharyngitis Pneumonia Ectopic pregnancy Trauma Sickle cell crisis Sickle cell crisis Ovarian/testicular torsion Henoch-Schönlein purpura Henoch-Schönlein purpura Mesenteric lymphadenitis Mesenteric lymphadenitis Adapted from : Acute Abdominal Pain in Children ALEXANDER K.C. LEUNG, DAVID L. SIGALET, American Family Physician® > Vol. 67/No. 11 (June 1, 2003)
  • 12. ABDOMINAL PAIN Causes of ACUTE ABDOMINAL PAIN in very young children • Neonates – acute abdomen • Intestinal volvulus • Incarcerated inguinal hernia • Hirschsprung's disease • Intussusception • Trauma – non-accidental
  • 13. Causes of Abdominal Pain in Children   Emergencies/life-threatening Other causes Medical causes Diabetic Ketoacidosis Gastroenteritis (bacteria or viruses) Inflammatory bowel disease Constipation Acute adrenal failure Flatulence   Mesenteric lymphadenitis   Peptic ulcer disease   Urinary tract infection   Ureteric calculi   Hepatitis   Cholecystitis   Pancreatitis   Sickle cell anaemia/crises   Henoch Schonlein purpura Surgical causes Appendicitis   Bowel obstruction (e.g.  intussusception, volvulus) Trauma Incarcerated hernia Peritonitis Testicular torsion Gynaecological causes   Dysmenorrhoea Mittelschmerz Pelvic inflammatory disease Endometriosis Obstetric causes Ectopic pregnancy   Ovarian cyst rupture/torsion Abortion Drugs/Toxins Paracetamol overdose Soap ingestion Iron overdose Erythromycin Venoms   Referred pain   Pneumonia Rare causes   Angioneurotic oedema Familial Mediterranean fever Unknown aetiology   Infantile colic Functional bowel disease
  • 14. ADMISSIONS 363 OPERATIONS 125 35% OTHER SURGICAL DIAGNOSES OR NEGATIVE 24 6% MEDICAL 129 35% APPENDICITIS 106 29% NON-SPECIFIC ABDOMINAL PAIN 108 30% OBSERVED 237 65% Admissions with Abdominal Pain to a District General Hospital in one year HOME CHEMIST NHS DIRECT GP
  • 15. Admissions with Abdominal Pain to a Paediatric Surgical Unit in one year
  • 16. • The most common medical cause is gastroenteritis • The most common surgical cause is appendicitis. ACUTE ABDOMINAL PAIN
  • 17. Pain & vomiting • In the acute surgical abdomen, pain generally precedes vomiting, while the reverse is true in medical conditions.
  • 18. • The most common medical cause is gastroenteritis – Viruses rotavirus, Norwalk virus, adenovirus, Enterovirus Bacteria Escherichia coli, Yersinia, Campylobacter, Salmonella, Shigella. ABDOMINAL PAIN
  • 19. Causes of Acute Abdominal Pain in Children Gastrointestinal causes Gastroenteritis Appendicitis Mesenteric lymphadenitis Constipation Flatulence Abdominal trauma Intestinal obstruction Peritonitis Food poisoning Peptic ulcer Meckel's diverticulum Inflammatory bowel disease Lactose intolerance Hernia Liver, spleen, and biliary tract disorders Hepatitis Cholecystitis Cholelithiasis Splenic infarction Rupture of the spleen Pancreatitis Genitourinary causes Urinary tract infection Urinary calculi Dysmenorrhoea Mittelschmerz Pelvic inflammatory disease Threatened abortion Ectopic pregnancy Ovarian/testicular torsion Endometriosis Hematocolpos Metabolic disorders Diabetic ketoacidosis Hypoglycaemia Porphyria Acute adrenal insufficiency Hematologic disorders Sickle cell anemia Henoch-Schönlein purpura Haemolytic uremic syndrome Drugs and toxins Erythromycin Salicylates Lead poisoning Venoms Iron overdose Soap ingestion Pulmonary causes Pneumonia Diaphragmatic pleurisy Miscellaneous Infantile colic Functional pain Pharyngitis Angioneurotic oedema Familial Mediterranean fever Floating Rib Syndrome Adapted from : Acute Abdominal Pain in Children ALEXANDER K.C. LEUNG, DAVID L. SIGALET, American Family Physician® > Vol. 67/No. 11 (June 1, 2003)
  • 20. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN
  • 21. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Up to 20% of infants First 6 months Scream Draw knees up
  • 22. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Over diagnosed Pain – Visceral / LIF Acute – organic cause Chronic – functional cause Diagnosis of last resort
  • 23. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Adenovirus Preceding upper resp infectionMay Other lymphadenopathy mimic appendicitis Pain more diffuse Higher temperature Shifting tenderness
  • 24. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN ACCIDENTAL NON-ACCIDENTAL Parents may conceal information
  • 25. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Includes •Malrotation •Volvulus •Intussusception •Incarcerated hernia •adhesions
  • 26. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Includes •Malrotation •Volvulus •Intussusception •Incarcerated hernia •Adhesions – ACQUIRED -- CONGENITAL
  • 27. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Chlamydia Neisseria infection and inflammation of the upper female genital tract, uterus, fallopian tubes and ovaries. infection in the vagina & cervix passing to the internal reproductive organs. Age 15 to 24 2% female population 20% recurrent
  • 28. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Chlamydia Neisseria AND Pregnancy History may be concealed
  • 29. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN Chlamydia Neisseria AND Pregnancy History may be concealed PregnancyPregnancy 10% occur in 13 to 15 (7.8 per 1000)10% occur in 13 to 15 (7.8 per 1000) 52% occur in 13 to 17 (41 per 1000)52% occur in 13 to 17 (41 per 1000)
  • 30. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN NICE Guidelines -August 2007 www.nice.org.uk/Guidance/CG54/NiceGuidance/pdf/English
  • 31. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN NICE Guidelines -August 2007 e Symptoms and signs Most common Least Common Preverbal Fever Abdominal pain Loin tenderness Vomiting Poor feeding Lethargy Irritability Haematuria Offensive urine Failure to thrive Verbal Frequency Dysuria Dysfunctional voiding Changes to continence Abdominal pain Loin tenderness Fever Malaise Vomiting Haematuria Offensive urine Cloudy urine
  • 32. • Infantile colic • Constipation • Mesenteric adenitis • Abdominal trauma • Intestinal obstruction • Pelvic inflammatory disease • Urinary Tract Infection • Meckel’s Diverticulum ABDOMINAL PAIN
  • 34. Meckel’s Diverticulum • Meckel's diverticulum, • congenital • remnant of the vitelointestinal duct (omphalomesenteric duct) • 2 feet (from the ileocecal valve) • 2 inches (in length) • 2% (of the population) have it • 2% are symptomatic • 2 is the most common age at clinical presentation • 2:1 male:female • 2 types of common ectopic tissue (gastric and pancreatic) • first described by Fabricius Hildanus C16first described by Fabricius Hildanus C16 • named after Johann Friedrich Meckelnamed after Johann Friedrich Meckel who described the embryological originwho described the embryological origin of this type of diverticulum in 1809of this type of diverticulum in 1809
  • 36. ABDOMINAL PAIN • History • A challenge in young children • poor sense of timing and location
  • 37. ABDOMINAL PAIN • History • PAIN Location • Onset • Character • Change of location or character • Severity • Radiation • Precipitating/relieving factors
  • 38. ABDOMINAL PAIN • History • VOMITING character • frequency • content bile / blood • BOWELS frequency • consistency • blood • URINARY frequency/dysuria/polyuria/urgency/odour/colour • RESPIRATORYcough/SOB/chest pain • GENERAL temperature/headache/joint pains-swelling/rash/sore throat • GYNAE menstruation/LMP/sexual activity/contraception/vaginal discharge/?midcycle • PAST MEDICAL HISTORY / DRUG HISTORY / FAMILY HISTORY
  • 39. ABDOMINAL PAIN • Examination • GENERAL APPEARANCE • GENERAL – ENT • – Chest • ABDOMINAL Breathing pattern • distension • Point to pain • Maximum tenderness • Muscle guarding • Rebound tenderness • bowel sounds • groin / testes / introitus • Rectal Examination
  • 40. ABDOMINAL PAIN • Investigations • Tailored to symptoms and signs • CONSIDER Full Blood Picture • Differential White Cell Count • Urinalysis • CRP • Pregnancy Test • • Abdominal X-Ray • Chest x-Ray • Ultrasound • CT
  • 42. ABDOMINAL PAIN “repeated physical examination by the same physician often is useful”
  • 43. ABDOMINAL PAIN repeated physical examination is MANDATORY by the same physician is BENIFICIAL
  • 47. • in most instances, abdominal pain can be diagnosed through the history and physical examination.
  • 48. ‘THE PAIN’ in ABDOMINAL PAIN • Use analgesia as required - it does not affect diagnostic accuracy Patient UK at www.patient.co.uk/showdoc/40000523/
  • 49. ‘THE PAIN’ in ABDOMINAL PAIN • Traditionally, the use of analgesics is discouraged in patients with abdominal pain for fear of interfering with accurate evaluation and diagnosis. • However, several prospective, randomized studies have shown that judicious use of analgesics actually may enhance diagnostic accuracy by permitting detailed examination of a more cooperative patient.
  • 52. The approach to common abdominal diagnosis in infants and children Irish M S et al Pediatric Clin North Am. 1998 Aug: 45(4): 729-72 % PERFORATED % NORMAL Age <= 8 years 33 13 Age > 8 years 18 11 Male 22 8 Female 18 17
  • 53. Age in Years 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 Acute appendicitis without perforation 2 8 17 30 33 17 43 57 97 111 137 168 144 163 104 91178 Acute appendicitis with perforation 2 3 10 23 20 16 16 23 27 25 16 16 12 22 8 18 42 Total number of patients 4 11 27 53 53 33 59 80 124 136 153 184 156 185 112 109220 Percentage perforated 50 27 37 46 38 48 27 27 22 18 10 9 8 12 7 17 19
  • 55. APPENDICITIS • Types of Appendicitis pathogenesis primary obstruction of the lumen of appendix filled with mucus and swells. increasing pressure within the lumen Pressure on the wall of the appendix resulting in thrombosis & occlusion of blood vessels Inflammation of appendix Pus may form within the appendix (suppuration) stasis of lymph flow - leads to ischaemia and necrosis (gangrene) Bacteria begin to leak out through appendix walls Pus forms within and around the appendix Perforation of appendix - peritonitis / abscess Septicaemia - death }Appendix Mass
  • 56.
  • 57. APPENDICITIS • Types of Appendicitis – Acute – Perforated
  • 58. APPENDICITIS • Types of Appendicitis – Acute • Acute inflammatory appendicitis • Acute Suppurative appendicitis – Perforated (complicated) • Perforated • Gangrenous
  • 59. APPENDICITIS • Types of Appendicitis – Acute • Acute inflammatory appendicitis • Acute Suppurative appendicitis – Perforated (complicated) • Perforated • Gangrenous • Normal • (Registrar’s Appendicitis)
  • 60. APPENDICITIS • Types of Appendicitis – Acute • Acute inflammatory appendicitis • Acute Suppurative appendicitis – Perforated (complicated) • Perforated • Gangrenous • Normal Appendix Mass Appendix Abscess
  • 62. Clinical Features - Symptoms • Pain – Central » Vague » Crampy » Wants to move around – Moves to Right Iliac Fossa » Acute » Sharp / constant » Wants to lie still Anorexia Nausia Vomiting Mild Pyrexia Halitosis Change in bowel habit – diarrhoea -- constipation Urinary Symptoms LOCALISED
  • 64. Clinical Features - Signs • Localised Tenderness • Muscle Guarding Tachycardia Flushed Circum-oral pallor Rectal Examination ? Rovsing’s Sign Psoas sign Obturator sign Caecal Gurgle
  • 65. Clinical Features - Signs • Localised Tenderness • Muscle Guarding Tachycardia Flushed Circum-oral pallor Rectal Examination ? Rovsing’s Sign Niels Thorkild Rovsing Danish surgeon 1907, Psoas sign Obturator sign Caecal Gurgle
  • 66. Clinical Features - Signs • Localised Tenderness • Muscle Guarding Tachycardia Flushed Circum-oral pallor Rectal Examination ? Rovsing’s Sign Psoas sign Obturator sign Caecal Gurgle Action:- Hip flexion Pain:-Pain:- Hip ExtensionHip Extension
  • 67. Clinical Features - Signs • Localised Tenderness • Muscle Guarding Tachycardia Flushed Circum-oral pallor Rectal Examination ? Rovsing’s Sign Psoas sign Obturator sign Caecal Gurgle Action:- Abducts Lat Rotates Pain:-Pain:- Hip AdductionHip Adduction Internal RotationInternal Rotation
  • 68. Clinical Features - Signs • Localised Tenderness • Muscle Guarding Tachycardia Flushed Circum-oral pallor Rectal Examination ? Rovsing’s Sign Psoas sign Obturator sign Caecal Gurgle
  • 69. Clinical Features - Signs • Localised Tenderness • Localised Guarding
  • 70. Anatomical positions of appendix • Retrocaecal – poor localising signs • Retroileal – diarrhoea • Pelvic – diarrhoea / Bladder
  • 71. CLASSICAL CARDINAL FEATURES • Localised Pain • Localised Tenderness • Muscle Guarding • (Rebound Tenderness) McBurney’s Point Charles McBurney U.S. surgeon, 1845–1913
  • 72. Investigations • Blood Test – Sickle – Neutrophil leucocytosis – Lymphopenia – CRP
  • 73. Investigations • Radiology – Abdominal film • Obstruction • faecolith • Soft tissue mass • Loaded colon – Ultrasound • Gynaecological • Abscess/mass/thick bowel loops • stones
  • 74. APPENDICITIS • Preparation for theatre – Analgesics – Fluids – Antibiotics – Consent
  • 75. APPENDICITIS • In theatre – EUA • Open or Laparoscopic ?
  • 76. APPENDICITIS • In theatre – EUA • Open or Laparoscopic ? • What if it is perforated ?
  • 77. APPENDICITIS • In theatre – EUA • Open or Laparoscopic ? • What if it is Crohn’s ?
  • 78. APPENDICITIS • In theatre – EUA • Open or Laparoscopic ? • What if it is normal ?
  • 79. A few less common causes ofA few less common causes of ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN ACUTE ABDOMINAL PAIN IN CHILDRENACUTE ABDOMINAL PAIN IN CHILDREN
  • 80. Henoch-Schönlein purpura • systemic vasculitis • deposition of immune complexes containing the antibody IgA in the skin and kidney • occurs mainly in young children.
  • 81. Henoch-Schönlein purpura • self-limiting • no treatment - symptom control, • in a third of cases disease may relapse -irreversible kidney damage in about 1% of cases • Cause unknown, post viral and bacterial infections, / adverse drug reactions
  • 82. 12th Rib Syndrome • Floating Rib • Slipping Rib • Rib Dysfunction