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1. In The Panama Puzzle, which of the following approaches did the team use to try to determine
how yellow fever was spread?
a. They tried to show that mosquito could spread the disease from victims to human volunteers.
b. They tried to show the disease was not spread by personal possessions or clothing of victims
c. They tried to show that the disease was transmitted in the blood of victims.
d. They tried all 3 of these approaches
2. Which description of the origin and spread of SARS-CoV (from the 2002-2003 outbreak) and
of MERS-CoV is most accurate?
a. SARS-CoV originated in bats and spread via civets to humans, while MERS-CoV originated
in bats and spread via camels to humans
b. SARS-CoV originated in bats and spread directly to humans, while MERS-CoV originated in
bats and spread via mosquitos to humans
c. SARS-CoV originated in bats and spread via pangolins to humans, while MERS-CoV
originated in bats and spread via civets to humans
d. SARS-CoV originated in civets and spread via bats to humans, while MERS-CoV originated
in camels and spread via bats to humans
3. Where do the SARS-CoV-2 spike, envelope and membrane proteins combine with
nucleocapsid proteins?
a. in the endoplasmic reticulum-Golgi network (ERGIC)
b. in the cell cytoplasm
c. upon exiting the cell (exocytosis)
d. in the cell membrane
e. in the cell nucleus

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