BioMicroLab’s VolumeCheck™ models 100 & 50 for 96 well labware eliminates time intensive visual or pipette-based volume inspections by automating the QC/QA task of verifying volume in well plates and tube racks. The VolumeCheck uses non-contact ultrasonic measurement technology to detect sample volume before or after use on any liquid handling instrument, or tracks and records sample volume your lab receives or dispenses.
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Volume check 100 overview
1. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
96 Well LabwareVolumeCheck 50 &100
VolumeCheck100
Standalone Volume Detection for 96 well labware
2. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck100/50/384
Main Benefits
• Software interface provides visual reference
as to sample well volumes.
• Provides output file to track and validate
sample plate processing.
• Key method to quickly check wells for sample
volume prior to liquid handling operations.
• Detection of empty wells in a well plate
• Measurement of sample volumes in well
plate to evaluate if sufficient amount of
materials was provided
• Measurement of aspiration of critical
hardware parts
• Calibration of liquid handler and highlight of
specific patterns in the dispense
3. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck
• General purpose volume inspection system
• Utilizes one non-contact sensor
• Output data is the distance measured from sensor
to sample level
Technology Overview
• Measures the distance between
the sensor and the sample
meniscus with a non-contact
sensor.
• For Example: 15mm = 350µL
4. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck Technology Overview
5. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck
Workflow
6. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck
Typical Applications
▪ Production monitoring system to monitor
and validate
▪ Quality control system for liquid handling
operations
▪ Compound or sample library
volume/inventory management tool
Typical Customers
▪ Reagent manufacturers
▪ RNA / DNA synthesis
▪ Compound sample laboratories
▪ Biobanks or biorepositories
▪ Molecular diagnostics testing labs
Applications
7. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
• One non-contact sensor
• Detects volume in uncapped well plates and tube racks
• Works with water, alcohol, DMSO, TE, buffer, and other
common laboratory solutions
• Compatible racks: 96, 48, 24, 12 well formats
• For labware up to 52mm tall
Two Models
▪ VolumeCheck100
• One minute per 96 well tube rack
▪ VolumeCheck 50
• 3 minutes per 96 well tube rack
Features
VolumeCheck 100 & 50
8. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
SLAS standard size labware:
▪ 96 well
▪ 48 well
▪ 24 well
▪ 12 well
• Plates and racks need to be greater
than 45mm in height
▪ Optional rack adapters available
• Must be uncapped or uncovered
SLAS format well plates
Labware Compatibility
• Tube racks, well plates,
PCR plates, micro-titer
plates and others!
9. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 384/100/50
• One non-contact sensor
• Detects volume in uncapped well plates and tube racks
• Works with water, alcohol, DMSO, TE, buffer, and other common
laboratory solutions
Feature comparison
VolumeCheck 100 & 384 models
Feature VC 50 VC 100 VC 384
Labware 12,24,48,96 well 12,24,48,96 well 12,24,48,96, 384 well
Labware height Up to 52mm tall Up to to 52mm tall Up to 92mm tall
Rack Adapters For labware less than 45mm For labware less than 45mm Typically not needed
Speed 3 minutes for 96 tubes 1 minute for 96 tubes
Normal: 2- 2 ½ minutes for 384
High speed: 30 secs for 384
1 minute for 96 tubes
10. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
Main Processing Screen
• Load reference table
• Select specific wells to read
• Start and stop anytime
• Volume data displayed while scanning
• Graphical interface of volume detected
▪ Entire plate map
▪ Inspection by row
• Output file created at the end of each
plate scan
Software Features
11. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
Output File Options
▪ User-definable selection of
data to output
▪ Select output folder location
▪ Format: .csv, .txt, or user
defined
▪ Customer determines content
and order of data
Software Output Files
12. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
Example Output file
▪ File format - .csv, .txt, or user defined
▪ Customizable and user defined
Software Output Files
13. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
Print Report Feature
• One page includes
▪ Plate map
▪ Scan data
▪ Rack ID
▪ Time and date
▪ Calibration file info
• Output to computer’s default printer
• Output to PDF file
Software Features
14. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck 100&50
Plate Data Creator Utility
• Plate maps
▪ enter known volumes to plot
• Reference curve data collected
▪ data plotted on curve
• Curve fitting tools
▪ split curve to define upper and lower
segments for best data fit
▪ Remove outlying data points
Software Calibration Curves
15. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck
VolumeCheck SDK toolkit for custom integration
with other robotics or LIMS. Please ask for SDK
documentation!
Please see our list of
OEM partners for the VolumeCheck on our website.
Integrated with Hamilton (images compliment of Emerald Cloud Lab, SSF, CA)
16. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
VolumeCheck
Compare Models
VolumeCheck50 VolumeCheck100 VolumeCheck384
Speed 3 minutes per 96 wells 1 minute per 96 wells 2-3 minutes per 384 wells
Labware 24, 48 & 96 well SLAS formatted plates and
tube racks
> Up to 52mm height
24, 48 & 96 well SLAS formatted plates
and tube racks
> Up to 52mm height
24, 48, 96 & 384 well SLAS formatted plates
and tube racks
> Up to 92mm height
Best for Labs with low throughput Labs with high throughput Labs with diverse labware
Includes: Instrument, Software, Manual, Quick Start Guide, USB Cord
Requirements: Windows 10, 8, 7, 2 GB RAM, One USB Port
VC 50 & 100 Dimensions: 10.5” H x 10.3” W x 17.0” D (26cm x 26cm x 43cm) Weight: 27 lbs
VC 384 Dimensions: 11" W x 26.5" D x 12.5" H (28cm x 68cm x 32cm) Weight: 33.25
Electrical: 110-220 VAC 50/60Hz
17. BioMicroLab, Inc. | 2500-A Dean Lesher Dr. Concord, CA 94520 USA
925-689-1200 | sales@biomicrolab.com | www.biomicrolab.com
Contact BioMicroLab
Online www.biomicrolab.com
Email info@biomicrolab.com
Tel (925) 689-1200
Fax (925) 689-1263
Mail 2500-A Dean Lesher Drive
Concord, CA 94520 USA
BioMicroLab has been designing lab automation
equipment since 2001 and our team has a 20-year
track record in manufacturing material handling
products from our Northern California facility.
BioMicroLab has installed 100s of automated tube
handlers and 1,000s of sample management devices at
biotech and pharmaceutical companies, hospitals,
universities, genomic research facilities and biobanks
worldwide.
We are committed to offering reliable,
results-oriented and cost-effective
solutions to our customers.