vitamin A and its role of vision in the dim light.pdf

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All trans retinal
Retinal reductase
All trans retinol
Closure of Na+ channels of outer segment
Intracellular potential becomes more –ve
(hyperpolarization)
Initiation nerve impulse from receptors of retina to optic nerve to brain
Biochemistry of special sense
modules MEQ
BY/Mohamed Ali
Dr /Mohamed Ali

Rhodopsin Bathorhodopsin
Light energy
Lumirhodopsin
Metarhodopsin 1
Metarhodopsin 2
All trans retinal
Opsin
Retinal reductase
All trans retinol
In liver
Isomerase
11-cis retinol
Retinal oxidase
11-cis retinal
Activation of transducin
Activation of c-GMP phosphodiesterase
Hydrolysis of c-GMP → ↓ c-GMP & ↑ GMP
Closure of Na+ channels of outer segment
Intracellular potential becomes more –ve
(hyperpolarization)
Initiation nerve impulse from receptors of retina to optic nerve to brain
Explain role of vitamin A in vision
Visual cycle
MEQ
By/ Mohamed Ali

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vitamin A and its role of vision in the dim light.pdf

1. All trans retinal Retinal reductase All trans retinol Closure of Na+ channels of outer segment Intracellular potential becomes more –ve (hyperpolarization) Initiation nerve impulse from receptors of retina to optic nerve to brain Biochemistry of special sense modules MEQ BY/Mohamed Ali Dr /Mohamed Ali

2. Rhodopsin Bathorhodopsin Light energy Lumirhodopsin Metarhodopsin 1 Metarhodopsin 2 All trans retinal Opsin Retinal reductase All trans retinol In liver Isomerase 11-cis retinol Retinal oxidase 11-cis retinal Activation of transducin Activation of c-GMP phosphodiesterase Hydrolysis of c-GMP → ↓ c-GMP & ↑ GMP Closure of Na+ channels of outer segment Intracellular potential becomes more –ve (hyperpolarization) Initiation nerve impulse from receptors of retina to optic nerve to brain Explain role of vitamin A in vision Visual cycle MEQ By/ Mohamed Ali

vitamin A and its role of vision in the dim light.pdf

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