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TOPIC - ANTI PARKINSON DRUGS
Presented by – Shobhit
Batch – B.pharm 3rd year
INTRODUCTION
• An Antiparkinsonian is an agent used in the treatment of
Parkinson's disease.
• Antiparkinsonians are intended to control the symptoms
of Parkinson's disease.
• Antiparkinsonians are used to treat the muscle stiffness
and tremor associated with Parkinson's disease.
CAUSES
• Family history
• Genetic mutation
• Protein misfolding
• Oxidative stress
• Mitochondrial dysfunction
SYMPTOMS
• Stiff muscles
• Difficulty standing
• Difficulty walking
• Fatigue
• Dizziness
• Amnesia
• Anxiety
• Weight loss
CLASSIFICATION
PHARMACOKINETIC OF LEVODOPA
• It is administered by orally.
• It absorbed from small intestine.
• The half life is 0.2 to 2 hours.
• It metabolized by dopa decarboxylase in GIT and blood vessels.
• It is excreted by Urine.
Adverse effect of Levodopa
• Dyskinesia
• Diarrhea
• Nausea Vomiting
• Constipation
• Abdominal Pain
• Orthostatic Hypotension
• Lethargy
• Psychosis
Shobhit (Antiparkinson disease)_032754.pptx

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Shobhit (Antiparkinson disease)_032754.pptx

  • 1. TOPIC - ANTI PARKINSON DRUGS Presented by – Shobhit Batch – B.pharm 3rd year
  • 2. INTRODUCTION • An Antiparkinsonian is an agent used in the treatment of Parkinson's disease. • Antiparkinsonians are intended to control the symptoms of Parkinson's disease. • Antiparkinsonians are used to treat the muscle stiffness and tremor associated with Parkinson's disease.
  • 3. CAUSES • Family history • Genetic mutation • Protein misfolding • Oxidative stress • Mitochondrial dysfunction
  • 4. SYMPTOMS • Stiff muscles • Difficulty standing • Difficulty walking • Fatigue • Dizziness • Amnesia • Anxiety • Weight loss
  • 6. PHARMACOKINETIC OF LEVODOPA • It is administered by orally. • It absorbed from small intestine. • The half life is 0.2 to 2 hours. • It metabolized by dopa decarboxylase in GIT and blood vessels. • It is excreted by Urine.
  • 7. Adverse effect of Levodopa • Dyskinesia • Diarrhea • Nausea Vomiting • Constipation • Abdominal Pain • Orthostatic Hypotension • Lethargy • Psychosis