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• To know the types of cartilage and their location in body.
• Understand the functional roles of each type of cartilage
• To be able to identify cartilage in a histology slide.
• Cartilage is a special type of connective tissue
• Cartilage serves as a shock absorber to protects joints and
bones
• No vessels or nerves
• Perichondrium present
• CELLS
- Chondroblasts
- Chondrocytes
Chondroblasts (Immature cartilage cell)
- Produce the components of extracellular matrix.
- Originate from a type of mesenchymal progenitor cells.
Chondrocytes (Mature cartilage cell)
- Nourishing and maintaining extracellular matrix
- Has lacuna
- Originated from the chondroblasts.
• EXTRACELLULAR MATRIX
- Connective tissue fiber
- Ground substance
Connective tissue fiber
- Collagen and Elastic fibers
• Ground substance (Gels)
- Glycosaminoglycans (GAGs)
- Hyaluronic acid
- Chondroitin sulfate
- Keratan sulfate
• Most common type
• Hyaline cartilage provides durable protection and supports movable joints
• End of Bones
• Embryonic Skeleton
• Costal Cartilages of the Ribs
• End of the nose
• Tracheal rings
• Perichondrium is characteristically absent.
• Found predominantly in the intervertebral disks of the spine.
• Has thick bundles of collagen fibers.
• Meniscus
• Intervertebral discs
• pubic symphysis
• Elastic cartilage provides flexible support that helps maintain the
shape of the organs.
• It has a yellowish colour and is surrounded by a perichnodrium.
• Abundance of elastic fibres makes it flexible and resilient.
• Epiglottis
• External ear
• Auditory tube
2 3
1
A
D
B
C
A
B
C
Histology of Bone - Cartilage (Connective Tissue)

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Histology of Bone - Cartilage (Connective Tissue)

  • 1.
  • 2. • To know the types of cartilage and their location in body. • Understand the functional roles of each type of cartilage • To be able to identify cartilage in a histology slide.
  • 3. • Cartilage is a special type of connective tissue • Cartilage serves as a shock absorber to protects joints and bones • No vessels or nerves • Perichondrium present
  • 4. • CELLS - Chondroblasts - Chondrocytes Chondroblasts (Immature cartilage cell) - Produce the components of extracellular matrix. - Originate from a type of mesenchymal progenitor cells. Chondrocytes (Mature cartilage cell) - Nourishing and maintaining extracellular matrix - Has lacuna - Originated from the chondroblasts.
  • 5. • EXTRACELLULAR MATRIX - Connective tissue fiber - Ground substance Connective tissue fiber - Collagen and Elastic fibers • Ground substance (Gels) - Glycosaminoglycans (GAGs) - Hyaluronic acid - Chondroitin sulfate - Keratan sulfate
  • 6.
  • 7. • Most common type • Hyaline cartilage provides durable protection and supports movable joints • End of Bones • Embryonic Skeleton • Costal Cartilages of the Ribs • End of the nose • Tracheal rings
  • 8.
  • 9. • Perichondrium is characteristically absent. • Found predominantly in the intervertebral disks of the spine. • Has thick bundles of collagen fibers. • Meniscus • Intervertebral discs • pubic symphysis
  • 10.
  • 11. • Elastic cartilage provides flexible support that helps maintain the shape of the organs. • It has a yellowish colour and is surrounded by a perichnodrium. • Abundance of elastic fibres makes it flexible and resilient. • Epiglottis • External ear • Auditory tube
  • 12.
  • 13. 2 3 1
  • 15. A B C