Reflection Of Creative Writing
Essay about Telescopes in Astronomy
Criticism by Imprisonment
Edith Whartons Use Of Setting
Essay On Gene Editing
Genome Editing Essay
Genome Editing Essay
Presiding Officer Training module 2024 lok sabha elections
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Essay Edit
1. Reflection Of Creative Writing
It is my belief that through this class and the tools provided, that my growth as a writer has grown
through leaps and bounds I would never have assumed possible. It is not so much the skill I refer
to, although I would think skill has gone up in some levels as well, but more so the appreciation for
the craft of writing itself. Intially, at the start of this class my sole goal was to further my
understanding and appreciation of the writer's and books that I so love to read. Through further
evaluation within the first week, a few other goals came to mind, of which were, making writing
a habit, finishing what I start, stop second guess my writing skills and making effective use of
detail and description. Through the use of the many articles, various reading materials, whether
poems or short stories, and especially through the workshop, I feel I was able to really push
myself to accomplishing these goals. I have thus far learned how important it is not to be skilled
at writing per say, but to have the will to write, that poetry is as much about it's sound as it is about
it's subject, just how important character development is, how the narration and point of view of a
story is essential to the way the story is told, and just how much of a difference peer's critiques can
make to your writing.
Since before the beginning of this creative writing course, I have always struggled to find a point to
writing. By this, I mean that I always felt that having great skill and talent was what was required
to be a writer, let alone a great one. From this point, I felt there was no need to continue my
writing as I felt that in a sense it just wasn't good enough. However, reading the article "A Way of
Writing", I found new hope. Here was a writer who says things such as "I must be willing to fail. If
I am to keep on writing, I cannot bother to insist on high standards. I must get into action and not let
anything stop me, or even slow me much"(Stafford) and quotes that writers don't necessarily have
any special talent. The article "Why I Write" instilled further optimism through the authors view on
just being a writer, not focusing on being good or bad. I found her words in which she writes
"entirely to find out what I'm
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2. Essay about Telescopes in Astronomy
Telescopes in Astronomy
Once upon a time, we believed the Earth was at the center of our universe. We were seriously
mistaken. We have come to find that at the center of most galaxies is a giant black hole that keeps
everything together. With the use of telescopes, we have made it possible to see the "impossible".
We are able to see the geographic landscape of distant planets and moons.Telescopes have made it
possible to measure the speed of light, understand gravity, and grasp other laws of physics. Will the
innovation of telescopes, we can detect stars by studying the heat and what kind of radioactive rays
they emit. It is exciting to think of how our knowledge of the heavens will be greatened in the future
with the development of...show more content...
Optical and infrared telescope need to be in warm, high areas to be most effective. High altitude
is key, to avoid local weather and atmospheric activities. Building telescopes in on the west coast
in also popular to avoid pollutants in the air. Radio telescopes are most effective in low valleys.
These valleys help block radio rays from outside sources. Radio frequency interference continues to
become an arising problem with these kinds of telescopes. More of these telescopes will be built in
less populated areas (such as Australia) in order to insure efficiency.
Telescopes in space are an essential resource for detecting ultraviolet, X–rays, and gamma rays for
our research. With telescopes in space, we avoid atmospheric issues and get clearer images from
space. Unfortunately, these telescopes cost a lot of money. Their lifespan is also affected
depending on how much fuel the telescopes can carry. There is also a great risk when launching
these telescopes. Many of these missions have failed at the launch point. Once in space, these
telescopes can be damaged from debris in space, solar flares, or even cosmic rays. Size is also an
issue. It takes certain elements to make sure that these telescopes and their mirrors don't warp when
in space. This turns out to be yet another expensive factor. Maintenance and upgrades are usually
pretty simple for ground level telescopes. When it comes to the one's in space, it is nearly
impossible to maintain
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3. Criticism by Imprisonment
Francis Scott Fitzgerald and Edith Wharton authored novels that take place in America around the
beginning of the nineteenth century. In both This Side of Paradise and The House of Mirth, the
authors paint the protagonists as imprisoned. This is a criticism of the society that they live in
and is represented in the authors' use of imagery, characterization, and the motif of social
standing. Wharton uses a great deal of imagery to reflect Lily Bart as imprisoned, while
Fitzgerald uses less imagery to describe Amory's predicament but still has his character as a
prisoner. In The House of Mirth, Lily is depicted by Selden as wearing bracelets that act as chains:
"[Lily] was so evidently the victim of the civilization that had produced her,...show more content...
(Fitzgerald 147–148).
With Amory's loss of love for Eleanor, Fitzgerald couples the loss with the idea of a mirror. Within
this idea, Fitzgerald expresses that Amory only loves that which reflects himself, and through that
reflection he is able to find who he is at the moment. However, with the broken perfection of
Eleanor comes the broken mirror and the losing of himself. Fitzgerald creates Amory's personality
to only know himself when he is with other people; in essence he is Fitzgerald's description of a
personality. This interpretation continues with Fitzgerald's foreshadowing that Amory will find
himself with another woman in the last line. Fitzgerald's criticism lies in the knowledge that
people go about life only looking to find themselves in others instead of introspection. Through
characterization, both of the authors offer their criticism, one for society and the other for
individuals. In both novels, the authors depict the motif of the importance of social standing.
With Wharton, this exists in Rosedale's marriage denial: " 'I'm more in love with you [Lily] than
ever, but if I married you now I'd queer myself for good and all, and everything I've worked for all
these years would be wasted" (Wharton 245–246). From this rejection, Wharton expresses the belief
that love means nothing
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4. Edith Wharton's Use Of Setting
When one hears the word "winter", one might think of a cold, peaceful environment. In the
beginning of the novel, the wintery environment present in Starkfield, Massachusetts has an elegant
and appealing nature. However, Edith Wharton reveals how this seemingly peaceful environment
can twist a whole community and provide an unpropitious future for the residents there. By using the
theme of winter, Wharton attempts to create a tranquil setting; however, as the story progresses
Starkfield begins to turn into a bleak, ironic setting that buries each characters desires and dreams.
Wharton uses the subject of winter to create a sensation of irony. When the narrator first enters
Starkfield, Massachusetts his first impression is how the atmosphere
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5. Essay On Gene Editing
This article discusses scientists from Oregon Health and Science University who successfully edited
the DNA of human embryos to eliminate a mutant gene of a heritable heart condition, using gene
editing technology known as Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR).
They focused on an inherited heart disease called hypertrophic cardiomyopathy, which is the
potential thickening of the heart muscle. The procedure consisted of using molecular scissors to cut
out the mutation in the sperm right before it fertilized the egg. The embryo then repaired the cut in
the sperm's genetic material by copying the egg's healthy gene, leaving the embryo free of a genetic
disease that would otherwise be passed down by the father. It...show more content...
One way I can expand my understanding of this topic is through additional research on the
development of human embryos and in vitro fertilization.
This article is based on a scientific discovery, made by scientists from Michigan State University,
whose objectives are to create an effective male birth control pill. Focussing on the causes of male
infertility, Chen Chen PhD., who is an assistant professor of animal science at MSU, as well as his
team, used a new gene editing technology on mice to effectively and completely block the gene,
PNLCD1, that controls sperm production, causing infertility. Thus, since mice and humans are both
mammals and use many of the same genes during reproduction, it is believed that this approach
could be effective in developing a human male contraception. I would like to further expand my
knowledge on this topic by doing additional research on the development of male contraceptives in
order to clarify a few of the questions that arose for me while reading this article. Will this drug
cause any harmful side effects on other tissues or organs within the human body? How effective will
this contraceptive method be?
This newsletter covers the story of a successful development of an advanced new imaging technique,
which can help assess the quality of early–stage embryos. Researchers at the ARC Centre of
Excellence for
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6. Genome Editing Essay
Introduction
Genome editing is a huge leap forward in science and medicine. Because of recent advances in
technology, the study of genes and induced 'point' mutations have led to the discovery and
advancement of methods previously used in order to mutate genes. The development of Clusters
of Regularly Interspaced Short Palindromic Repeats (CRISPRs) and CRISPR associated system 9
protein (Cas9) technology is a hugely significant leap forward as this is a tool that could potentially
be used for the research into and hopefully the treatment of a range of medical conditions that are
genetically related. Cystic fibrosis (Schwank, G. et al, 2013), haemophilia and sickle cell disease are
an example of some of the conditions that have the...show more content...
Once the complex was bound to the DNA, a cut would be made to eliminate and destroy the
invaders. 83% of archaeal genomes and 45% of bacterial genomes (Shabbir, M. et al, 2016) were
shown to be able to successfully utilize the CRISPR Cas9 system. These are very promising
statistics, so it is no wonder that there has been such an advancement in the past few years to bring
this technology to eukaryotic cells, mammalian cells and eventually human cells.
With the rate and volume that new experiments and experimental procedures are being tried and
tested, it can be expected that a Nobel Prize will soon be won for the discovery and advancement of
this potential life–saving 'tool'. The category of Nobel Prize and who it potentially should be
awarded to are discussed later in this essay.
The Role of CRISPR/Cas9 as a Genome Editing Tool
There are three types of CRISPR systems. The Type II CRISPR system (where the interface is
mediated by a single large protein in conjunction with crRNA) is the simplest of the three and it is
this one that has been the basis for genome editing.
The Cas9 protein is an enzyme that effectively acts as a pair of molecular 'scissors', cutting
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7. Genome Editing Essay
Genome editing of germ line cells using CRISPR/Cas9 system
Recent studies suggest that genome editing of germ line cells is an effective strategy for mutated
gene correction in sperms and oocytes for the inhibition of onset of inherited disorder. The first time,
germ line genome editing in human by CRISPR/Cas9 system , was carried out to correct mutation
of HBB (Beta globin) gene in zygote of ОІ–thalassemia patients by homologous DNA
recombination (HDR) [80, 81]. Embryonic genome editing utilized in the treatment of such
monogenic diseases prior to birth is a rational use of embryonic genome editing in germ line cells.
Homologous DNA recombination by traditional gene editing techniques in mammalian eggs has a
low rate (<10%) in term of...show more content...
Because PGD usually is carried out by gametes prepared from parents. But parents who is confirmed
by PGD to have a high risk of transmition of inherited genetic mutation to their children and want to
have their own children, their gametes can be edited directly by Crisper/cas9 to create healthy
children.Nowdays germ line genome editing by programmable nuclease such as Crisper/cas9 is the
most useful tool to treat genetic diseases with high risk of inheritance mutation transmition.
Unresolved ethical problems still exist and are the main reason for delay onset of clinical trials in
this field. Large animal models can be utilized for a variety of monogenic diseases, particularly
monogenic neurological disorders like HD and Duchene muscular dystrophy) DMD (. Specificity,
efficacy, and side effects of germ line genome editing technology should be assessed by animal
models before entering clinical trials.
Generating mammalian models of neurodegenerative diseases using CRISPR/Cas9
Cas9 has been well studied. It belongs to the class II CRISPR/Cas system which is the main protein
involved in small interfering CRISPR RNA (crRNA). CRISPR RNA often leads to the silencing of
invader viruses and plasmids [72, 85]. Several in vitro surveys have shown that Cas9 is guided by
gRNA composed of chimeric RNA. Chimeric RNA is composed of crRNA and tracrRNA. They are
sufficient to
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