DIFINITION Pastes are ointment like semisolid dosage forms insoluble solids as much as 50% by weight type Advantages Easily washable with water Form a protective coating Contains more concentration : disadvantaged Spreading is low Stored in a close container Very stiff. Uses Protect the skin Emollient effect retention of moisture vehicle Cleansing effect Classification (O/W)vanishing cream More comfortable Cosmetically acceptable Less greasy and easier to wash W/O Cold cream More difficult to handle Many drugs which are incorporated into creams are hydrophobic Can by moisturizing Definition Creams are semisolid preparations Indicted for application to the skin and mucus membrane such as those of the rectum or vagina Semisolid emulsion which are mixture of (O/W) and (W/O) creams Definition Creams are semisolid preparations Indicted for application to the skin and mucus membrane such as those of the rectum or vagina Semisolid emulsion which are mixture of (O/W) and (W/O) creams Aqueous Gel Pastes Toothpaste

1. Creams and pastes

2. Creams
DIFINITION
Pharmaceutical creams are semisolid
preparations containing one or more
medicinal agents dissolved in either
an o/w or w/o emulsion
application to the skin used for
.
external use

3. CREAMS
Basic
Components
Preservatives
Fragrances
Humectants
Emolsfying agent

4. Usage
CREAMS
1
•
Protective effect
•
EX: Sunscreen
2
•
Therapeutic effect
•
EX :Hormones cream
3
•
Cosmetic effect
•
Vanishing cream
EX:

5. CREAMS
Types
O/W Cream
•
Vanishing cream
W/O Cream
•
Cold cream

6. CREAMS
Vanishing cream
Vanishing cream is o/w cream we
called vanishing because it disappeared
when we rubbed on the skin and that's
happening because the water evaporate
.
leaving thin film of stearic acid
.
It has soap emulsifying agent

7. CREAMS
Cold
cream
Cold cream : it's a w/o cream
use for dry skin ,has cooling
effects cause the internal phase
(water) evaporate it must be use
at night because of the external
phase (oil) can attract dust , the
emulsifying agent is soap by
.
saponification

8. Pastes
DIFINITION
Pastes are ointment like semisolid dosage
forms that contain higher percentage of
insoluble solids as much as 50% by weight
that are more stiff than creams used for
external use and the common form of
.
paste is toothpaste

9. Pastes
Types
Aqueous Gel Pastes
•
Toothpaste
•
Gelatin
Fatty Paste
•
Zinc Oxide

10. Advantages
Easily washable
with water
Form a
protective
coating
Contains more
concentration
Pastes

11. Disadvantages
Spreading
is low
Stored in
a close
container
Very stiff.
Pastes

12. Toothpaste
Pastes
Toothpaste is a paste or gel dentifrice used
to clean and maintain the aesthetics and it
health of teeth and can removal
.
of dental plaque and food from teeth

13. Pastes
basic
components
.
* Humectant
.
* Abrasive
.
* Preservative
* Sweetening agent .
.
* Binders
* Sodium fluoride
.
(NaF)
.
* Flavoring agents

14. Pastes
Gelatin Pastes
It is a jelly paste when it is applied
to the skin we should melt in
water bath before use it and
covered it with a bandage remain
.
in place up to six weeks
Glycerogelatin pastes contain 10%
.
of the medicinal agent

15. Pastes
Jelly
vs.
Fatty
Pastes
* Fatty Pastes consist of fatty
bases like petrolatum also they
used chiefly as vehicles for
antiseptic and astringents for
.
example zinc oxide pastes
* Jelly pastes consist of
aqueous gel bases like
glycerin they can be applied
to moist surface for example
.
toothpastes

16. COMPARISION
Paste
Cream
Ointment
It is basicallyan ointment where
a high percentage of insoluble
solids are added
Mostly water-basedwhere
drugs are loaded in O/W or
W/O emulsion
Hydrocarbon based
greasy semisolid
Opaque
Opaque
Translucent to opaque
Less greasy
Less greasy
Greasy