SlideShare a Scribd company logo
1 of 24
KAZAKH NATIONAL MEDICAL UNIVERSITY NAMED AFTER S.D. ASFENDYAROVA
Almaty - 2023
Radiological semiotics of cholelithiasis
Plan
2
KazNMU named after . S.D.ASFENDIYAROVA
•Definition
•Pathogenesis
•Classification
•Anatomy of the gallbladder
•Diagnostic methods
•Radiological semiotics
•Differential diagnosis
•Recommendations
Cholelithiasis (cholelithiasis, or, as they are incorrectly called, gallstones)
3
KazNMU named after . S.D.ASFENDIYAROVA
This is a disease associated with a disorder in the metabolism of cholesterol and bilirubin , resulting in the formation
of stones in the gall bladder ( cholecystolithiasis ) and/or in the bile ducts ( choledocholithiasis ).
4
KazNMU named after . S.D.ASFENDIYAROVA
mixed
Types of
gallstones
pigmented cholesterol
5
KazNMU named after . S.D.ASFENDIYAROVA
Anatomy of the gallbladder and bile ducts
neck of the gallbladder
cystic duct
gallbladder
body
common bile duct
common
hepatic duct
sphincter muscles
bottom of the
gallbladder
hepatopancre
atic ampulla
pancreatic duct
FREQUENT LOCALIZATION OF STONES
6
KazNMU named after . S.D.ASFENDIYAROVA
gallstone location options
this moving stone periodically
wedges into the mouth of the
gallbladder causes biliary colic
stones in the
intrahepatic bile
ducts are rare
cystic duct stone
stones in the common
bile duct - the cause of
jaundice
stones in
gallbladder this stone simultaneously blocks
both the common bile duct and
the pancreatic duct
Research methods
7
KazNMU named after . S.D.ASFENDIYAROVA
Ultrasound (gold standard)
Radiography
CT
MRI
Endoscopic retrograde
cholangiopancreatography
Ultrasound semiotics of cholelithiasis
8
KazNMU named after . S.D.ASFENDIYAROVA
A highly reflective echogenic focus
in the lumen of the gallbladder ,
usually with pronounced posterior
acoustic shadowing, regardless of
the type of pathology (acoustic
shadowing is independent of the
composition and calcium content)
Gravity- dependent movement is
often observed when the patient
changes position ( RollingStone
sign )
9
KazNMU named after . S.D.ASFENDIYAROVA
Color Doppler can demonstrate
Shimmering artifact and especially useful for identifying small
stones
10
KazNMU named after . S.D.ASFENDIYAROVA
An accumulation of stones is detected in the neck
of the gallbladder , casting an acoustic shadow
Multiple floating
Gallbladder stones .
11
KazNMU named after . S.D.ASFENDIYAROVA
Radiography
X-ray data of stones in
Gallbladder ( cholelithiasis ):
• X-ray contrast pigment
stones: 50%
• Radiopaque cholesterol stones: 5%
CT scan for gallstones
12
KazNMU named after . S.D.ASFENDIYAROVA
CT without contrast enhancement :
-Calcareous stones of the gallbladder have a greater density compared to
bile
-Pure cholesterol stones have a lower density; There is an inverse
relationship between cholesterol levels and X-ray attenuation:
-May have the same density as bile and not be detected on CT
-The central part of the stone may contain nitrogen gas: a symptom of
the Mercedes-Benz
13
KazNMU named after . S.D.ASFENDIYAROVA
On an axial computed
tomogram without
contrast, a cluster of
layered and faceted
stones is determined in
the gallbladder .
14
KazNMU named after . S.D.ASFENDIYAROVA
In a patient with acute
calculous
cholecystitis on the axial
A computed tomogram with
contrast shows thickening of
the gallbladder wall and
calcified stones.
15
KazNMU named after . S.D.ASFENDIYAROVA
ABDOMEB CT WITH CONTRAST
The patient's sagittal computed tomogram and 3D reconstruction reveal a large
calcified calculus.
16
KazNMU named after . S.D.ASFENDIYAROVA
MRI FOR GALLBLADDER STONES
T1 – pigmented stones ( hyperintense )
- cholesterol stones ( hypointense )
• T2-VI:
A small focus of absent or weak signal limited to highly echogenic bile
within the gallbladder
• MRcholangiopancreatography :
Round lesions of absence of intragallbladder
17
KazNMU named after . S.D.ASFENDIYAROVA
Axial T2 HASTE in a slightly
thickened gallbladder, multiple
stones giving a weak signal are
determined.
18
KazNMU named after . S.D.ASFENDIYAROVA
Small area of absent or weak signal limited to highly echogenic bile, inside the
gallbladder
19
KazNMU named after . S.D.ASFENDIYAROVA
MR tomograms in the axial and frontal planes. Cholelithiasis. Gallstones in the gallbladder cavity are
characterized by a lack of signal within the gallbladder
on T2-VI and STIR
20
KazNMU named after . S.D.ASFENDIYAROVA
Endoscopic retrograde cholangiopancreatography
Mobile filling defects
inside
Contrast-filled gallbladder
blisters and stones in the
extrahepatic bile ducts
ERCP
sensitivity 68
- 93%
tubular stenosis of the common
bile duct with reflux of contrast
into the main hepatic duct against
the background of cholelithiasis
expansion of the pancreatic
duct and branches of the 2nd
and 3rd order, uneven contours
of the duct and branches
21
KazNMU named after . S.D.ASFENDIYAROVA
Forforan gallbladder
General characteristics:
• Best diagnostic criterion:
o Calcification in the form of a curved “rim”
in the right hypochondrium, resembling the
shape of a gallbladder
• Morphology:
Two options:
- Limited mucosal calcification: high risk of
malignancy
- Diffuse wall calcification: low risk of
malignancy
22
KazNMU named after . S.D.ASFENDIYAROVA
DIFFERENTIAL DIAGNOSTICS
Gallbladder polyp
Bladder bile sludge
Gallbladder carcinoma
Focal adenomyomatosis
Parasitic infestation of the gallbladder
Intestinal gases
Emphysematous cholecystitis
23
KazNMU named after . S.D.ASFENDIYAROVA
VISUALIZATION GUIDELINES:
Ultrasound is the best imaging modality for evaluating patients with upper abdominal pain/discomfort.
➢When evaluating patients with pain/discomfort in the upper right quadrant of the abdomen after a
fatty meal, especially middle-aged obese women , remember the likely presence of cholelithiasis
➢Tips for interpreting images:
the acoustic shadow they cast is of great importance
- Stones that do not cast a shadow can be mistaken for other formations of the gallbladder, for
example, polyp, sludge , carcinoma
- Shrinking, stone-filled gallbladder: assess for wall-echo-shadow sign or examine interlobar fissure
Thank you for attention!
​Mr. Almaty, st. Tole bi, 94
+7 727 338 70 90
www.kaznmu.kz
kaznmu@kaznmu.kz
KAZAKH NATIONAL MEDICAL UNIVERSITY NAMED AFTER S.D. ASFENDYAROVA
​@ kaznmu
https://
www.facebook.com/KazNMU
https://www.youtube.com/kaznmu _

More Related Content

Similar to Cholelithiasis full description radiology

Presentation1.pptx, radiological imaging of obstructive jaundice.
Presentation1.pptx, radiological imaging of obstructive jaundice.Presentation1.pptx, radiological imaging of obstructive jaundice.
Presentation1.pptx, radiological imaging of obstructive jaundice.Abdellah Nazeer
 
Biliary pathologies
Biliary pathologiesBiliary pathologies
Biliary pathologiesNavdeep Shah
 
Presentation1.pptx, abdominal film reading, lecture 111,
Presentation1.pptx, abdominal film reading, lecture 111,Presentation1.pptx, abdominal film reading, lecture 111,
Presentation1.pptx, abdominal film reading, lecture 111,Abdellah Nazeer
 
Obstructive jaundice hegazy
Obstructive jaundice hegazyObstructive jaundice hegazy
Obstructive jaundice hegazymostafa hegazy
 
Imaging of cystic duct
Imaging of cystic ductImaging of cystic duct
Imaging of cystic ductAli Jiwani
 
Imaging in Bowel ischemia
Imaging in Bowel ischemiaImaging in Bowel ischemia
Imaging in Bowel ischemiaGanesh Gadag
 
Cholecystitis and Choldocholithiasis
Cholecystitis and CholdocholithiasisCholecystitis and Choldocholithiasis
Cholecystitis and CholdocholithiasisNAVANEETA KUSUM
 
Radiologic mimics of cirrhosis
Radiologic mimics of cirrhosisRadiologic mimics of cirrhosis
Radiologic mimics of cirrhosisPankaj Kaira
 
radiologicmimicsofcirrhosis-161222165901.pdf
radiologicmimicsofcirrhosis-161222165901.pdfradiologicmimicsofcirrhosis-161222165901.pdf
radiologicmimicsofcirrhosis-161222165901.pdfDrYaqoobBahar
 
Gallbladder and Bile ducts Ultrasound
Gallbladder and Bile ducts Ultrasound Gallbladder and Bile ducts Ultrasound
Gallbladder and Bile ducts Ultrasound Moses Hadid
 
6. hepato biliary pancreatic.pptx
6. hepato biliary pancreatic.pptx6. hepato biliary pancreatic.pptx
6. hepato biliary pancreatic.pptxKollanur Charan
 
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)College of Medicine, Sulaymaniyah
 
A rare case of percutaneous therapeutic embolization of pancreatitis induced...
A rare case of percutaneous therapeutic embolization  of pancreatitis induced...A rare case of percutaneous therapeutic embolization  of pancreatitis induced...
A rare case of percutaneous therapeutic embolization of pancreatitis induced...WCER 2021
 
Imaging of dangerous cholecystitis
Imaging of dangerous cholecystitisImaging of dangerous cholecystitis
Imaging of dangerous cholecystitisAhmed Bahnassy
 
膽道系統炎症之影像診斷
膽道系統炎症之影像診斷膽道系統炎症之影像診斷
膽道系統炎症之影像診斷calaf0618
 
Vascular diseases of the liver by dr mohammed hussien
Vascular diseases of the liver by dr mohammed hussienVascular diseases of the liver by dr mohammed hussien
Vascular diseases of the liver by dr mohammed hussienKafrelsheiekh University
 
Radiological investigation of billiary tact 01
Radiological investigation of billiary tact 01Radiological investigation of billiary tact 01
Radiological investigation of billiary tact 01Kajal Jha
 

Similar to Cholelithiasis full description radiology (20)

Presentation1.pptx, radiological imaging of obstructive jaundice.
Presentation1.pptx, radiological imaging of obstructive jaundice.Presentation1.pptx, radiological imaging of obstructive jaundice.
Presentation1.pptx, radiological imaging of obstructive jaundice.
 
Biliary pathologies
Biliary pathologiesBiliary pathologies
Biliary pathologies
 
Presentation1.pptx, abdominal film reading, lecture 111,
Presentation1.pptx, abdominal film reading, lecture 111,Presentation1.pptx, abdominal film reading, lecture 111,
Presentation1.pptx, abdominal film reading, lecture 111,
 
Portal biliopathy
Portal biliopathyPortal biliopathy
Portal biliopathy
 
Obstructive jaundice hegazy
Obstructive jaundice hegazyObstructive jaundice hegazy
Obstructive jaundice hegazy
 
Imaging of cystic duct
Imaging of cystic ductImaging of cystic duct
Imaging of cystic duct
 
Imaging in Bowel ischemia
Imaging in Bowel ischemiaImaging in Bowel ischemia
Imaging in Bowel ischemia
 
Cholecystitis and Choldocholithiasis
Cholecystitis and CholdocholithiasisCholecystitis and Choldocholithiasis
Cholecystitis and Choldocholithiasis
 
Radiologic mimics of cirrhosis
Radiologic mimics of cirrhosisRadiologic mimics of cirrhosis
Radiologic mimics of cirrhosis
 
radiologicmimicsofcirrhosis-161222165901.pdf
radiologicmimicsofcirrhosis-161222165901.pdfradiologicmimicsofcirrhosis-161222165901.pdf
radiologicmimicsofcirrhosis-161222165901.pdf
 
Gallbladder and Bile ducts Ultrasound
Gallbladder and Bile ducts Ultrasound Gallbladder and Bile ducts Ultrasound
Gallbladder and Bile ducts Ultrasound
 
6. hepato biliary pancreatic.pptx
6. hepato biliary pancreatic.pptx6. hepato biliary pancreatic.pptx
6. hepato biliary pancreatic.pptx
 
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)
Radiology 5th year, 2nd lecture/cont. (Dr. Nasrin Alatrushi)
 
Sahad gb
Sahad gbSahad gb
Sahad gb
 
Urolithiasis pediatric
Urolithiasis  pediatricUrolithiasis  pediatric
Urolithiasis pediatric
 
A rare case of percutaneous therapeutic embolization of pancreatitis induced...
A rare case of percutaneous therapeutic embolization  of pancreatitis induced...A rare case of percutaneous therapeutic embolization  of pancreatitis induced...
A rare case of percutaneous therapeutic embolization of pancreatitis induced...
 
Imaging of dangerous cholecystitis
Imaging of dangerous cholecystitisImaging of dangerous cholecystitis
Imaging of dangerous cholecystitis
 
膽道系統炎症之影像診斷
膽道系統炎症之影像診斷膽道系統炎症之影像診斷
膽道系統炎症之影像診斷
 
Vascular diseases of the liver by dr mohammed hussien
Vascular diseases of the liver by dr mohammed hussienVascular diseases of the liver by dr mohammed hussien
Vascular diseases of the liver by dr mohammed hussien
 
Radiological investigation of billiary tact 01
Radiological investigation of billiary tact 01Radiological investigation of billiary tact 01
Radiological investigation of billiary tact 01
 

Recently uploaded

Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfAdmir Softic
 
Micro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfMicro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfPoh-Sun Goh
 
Unit-V; Pricing (Pharma Marketing Management).pptx
Unit-V; Pricing (Pharma Marketing Management).pptxUnit-V; Pricing (Pharma Marketing Management).pptx
Unit-V; Pricing (Pharma Marketing Management).pptxVishalSingh1417
 
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...christianmathematics
 
psychiatric nursing HISTORY COLLECTION .docx
psychiatric  nursing HISTORY  COLLECTION  .docxpsychiatric  nursing HISTORY  COLLECTION  .docx
psychiatric nursing HISTORY COLLECTION .docxPoojaSen20
 
1029-Danh muc Sach Giao Khoa khoi 6.pdf
1029-Danh muc Sach Giao Khoa khoi  6.pdf1029-Danh muc Sach Giao Khoa khoi  6.pdf
1029-Danh muc Sach Giao Khoa khoi 6.pdfQucHHunhnh
 
Class 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdfClass 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdfAyushMahapatra5
 
Application orientated numerical on hev.ppt
Application orientated numerical on hev.pptApplication orientated numerical on hev.ppt
Application orientated numerical on hev.pptRamjanShidvankar
 
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in DelhiRussian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhikauryashika82
 
ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.MaryamAhmad92
 
microwave assisted reaction. General introduction
microwave assisted reaction. General introductionmicrowave assisted reaction. General introduction
microwave assisted reaction. General introductionMaksud Ahmed
 
Unit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptxUnit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptxVishalSingh1417
 
Making and Justifying Mathematical Decisions.pdf
Making and Justifying Mathematical Decisions.pdfMaking and Justifying Mathematical Decisions.pdf
Making and Justifying Mathematical Decisions.pdfChris Hunter
 
Introduction to Nonprofit Accounting: The Basics
Introduction to Nonprofit Accounting: The BasicsIntroduction to Nonprofit Accounting: The Basics
Introduction to Nonprofit Accounting: The BasicsTechSoup
 
Seal of Good Local Governance (SGLG) 2024Final.pptx
Seal of Good Local Governance (SGLG) 2024Final.pptxSeal of Good Local Governance (SGLG) 2024Final.pptx
Seal of Good Local Governance (SGLG) 2024Final.pptxnegromaestrong
 
Mixin Classes in Odoo 17 How to Extend Models Using Mixin Classes
Mixin Classes in Odoo 17  How to Extend Models Using Mixin ClassesMixin Classes in Odoo 17  How to Extend Models Using Mixin Classes
Mixin Classes in Odoo 17 How to Extend Models Using Mixin ClassesCeline George
 
1029 - Danh muc Sach Giao Khoa 10 . pdf
1029 -  Danh muc Sach Giao Khoa 10 . pdf1029 -  Danh muc Sach Giao Khoa 10 . pdf
1029 - Danh muc Sach Giao Khoa 10 . pdfQucHHunhnh
 
General Principles of Intellectual Property: Concepts of Intellectual Proper...
General Principles of Intellectual Property: Concepts of Intellectual  Proper...General Principles of Intellectual Property: Concepts of Intellectual  Proper...
General Principles of Intellectual Property: Concepts of Intellectual Proper...Poonam Aher Patil
 

Recently uploaded (20)

Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdf
 
Micro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdfMicro-Scholarship, What it is, How can it help me.pdf
Micro-Scholarship, What it is, How can it help me.pdf
 
Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024Mehran University Newsletter Vol-X, Issue-I, 2024
Mehran University Newsletter Vol-X, Issue-I, 2024
 
Unit-V; Pricing (Pharma Marketing Management).pptx
Unit-V; Pricing (Pharma Marketing Management).pptxUnit-V; Pricing (Pharma Marketing Management).pptx
Unit-V; Pricing (Pharma Marketing Management).pptx
 
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
 
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptxINDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
INDIA QUIZ 2024 RLAC DELHI UNIVERSITY.pptx
 
psychiatric nursing HISTORY COLLECTION .docx
psychiatric  nursing HISTORY  COLLECTION  .docxpsychiatric  nursing HISTORY  COLLECTION  .docx
psychiatric nursing HISTORY COLLECTION .docx
 
1029-Danh muc Sach Giao Khoa khoi 6.pdf
1029-Danh muc Sach Giao Khoa khoi  6.pdf1029-Danh muc Sach Giao Khoa khoi  6.pdf
1029-Danh muc Sach Giao Khoa khoi 6.pdf
 
Class 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdfClass 11th Physics NEET formula sheet pdf
Class 11th Physics NEET formula sheet pdf
 
Application orientated numerical on hev.ppt
Application orientated numerical on hev.pptApplication orientated numerical on hev.ppt
Application orientated numerical on hev.ppt
 
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in DelhiRussian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
 
ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.ICT role in 21st century education and it's challenges.
ICT role in 21st century education and it's challenges.
 
microwave assisted reaction. General introduction
microwave assisted reaction. General introductionmicrowave assisted reaction. General introduction
microwave assisted reaction. General introduction
 
Unit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptxUnit-IV; Professional Sales Representative (PSR).pptx
Unit-IV; Professional Sales Representative (PSR).pptx
 
Making and Justifying Mathematical Decisions.pdf
Making and Justifying Mathematical Decisions.pdfMaking and Justifying Mathematical Decisions.pdf
Making and Justifying Mathematical Decisions.pdf
 
Introduction to Nonprofit Accounting: The Basics
Introduction to Nonprofit Accounting: The BasicsIntroduction to Nonprofit Accounting: The Basics
Introduction to Nonprofit Accounting: The Basics
 
Seal of Good Local Governance (SGLG) 2024Final.pptx
Seal of Good Local Governance (SGLG) 2024Final.pptxSeal of Good Local Governance (SGLG) 2024Final.pptx
Seal of Good Local Governance (SGLG) 2024Final.pptx
 
Mixin Classes in Odoo 17 How to Extend Models Using Mixin Classes
Mixin Classes in Odoo 17  How to Extend Models Using Mixin ClassesMixin Classes in Odoo 17  How to Extend Models Using Mixin Classes
Mixin Classes in Odoo 17 How to Extend Models Using Mixin Classes
 
1029 - Danh muc Sach Giao Khoa 10 . pdf
1029 -  Danh muc Sach Giao Khoa 10 . pdf1029 -  Danh muc Sach Giao Khoa 10 . pdf
1029 - Danh muc Sach Giao Khoa 10 . pdf
 
General Principles of Intellectual Property: Concepts of Intellectual Proper...
General Principles of Intellectual Property: Concepts of Intellectual  Proper...General Principles of Intellectual Property: Concepts of Intellectual  Proper...
General Principles of Intellectual Property: Concepts of Intellectual Proper...
 

Cholelithiasis full description radiology

  • 1. KAZAKH NATIONAL MEDICAL UNIVERSITY NAMED AFTER S.D. ASFENDYAROVA Almaty - 2023 Radiological semiotics of cholelithiasis
  • 2. Plan 2 KazNMU named after . S.D.ASFENDIYAROVA •Definition •Pathogenesis •Classification •Anatomy of the gallbladder •Diagnostic methods •Radiological semiotics •Differential diagnosis •Recommendations
  • 3. Cholelithiasis (cholelithiasis, or, as they are incorrectly called, gallstones) 3 KazNMU named after . S.D.ASFENDIYAROVA This is a disease associated with a disorder in the metabolism of cholesterol and bilirubin , resulting in the formation of stones in the gall bladder ( cholecystolithiasis ) and/or in the bile ducts ( choledocholithiasis ).
  • 4. 4 KazNMU named after . S.D.ASFENDIYAROVA mixed Types of gallstones pigmented cholesterol
  • 5. 5 KazNMU named after . S.D.ASFENDIYAROVA Anatomy of the gallbladder and bile ducts neck of the gallbladder cystic duct gallbladder body common bile duct common hepatic duct sphincter muscles bottom of the gallbladder hepatopancre atic ampulla pancreatic duct
  • 6. FREQUENT LOCALIZATION OF STONES 6 KazNMU named after . S.D.ASFENDIYAROVA gallstone location options this moving stone periodically wedges into the mouth of the gallbladder causes biliary colic stones in the intrahepatic bile ducts are rare cystic duct stone stones in the common bile duct - the cause of jaundice stones in gallbladder this stone simultaneously blocks both the common bile duct and the pancreatic duct
  • 7. Research methods 7 KazNMU named after . S.D.ASFENDIYAROVA Ultrasound (gold standard) Radiography CT MRI Endoscopic retrograde cholangiopancreatography
  • 8. Ultrasound semiotics of cholelithiasis 8 KazNMU named after . S.D.ASFENDIYAROVA A highly reflective echogenic focus in the lumen of the gallbladder , usually with pronounced posterior acoustic shadowing, regardless of the type of pathology (acoustic shadowing is independent of the composition and calcium content) Gravity- dependent movement is often observed when the patient changes position ( RollingStone sign )
  • 9. 9 KazNMU named after . S.D.ASFENDIYAROVA Color Doppler can demonstrate Shimmering artifact and especially useful for identifying small stones
  • 10. 10 KazNMU named after . S.D.ASFENDIYAROVA An accumulation of stones is detected in the neck of the gallbladder , casting an acoustic shadow Multiple floating Gallbladder stones .
  • 11. 11 KazNMU named after . S.D.ASFENDIYAROVA Radiography X-ray data of stones in Gallbladder ( cholelithiasis ): • X-ray contrast pigment stones: 50% • Radiopaque cholesterol stones: 5%
  • 12. CT scan for gallstones 12 KazNMU named after . S.D.ASFENDIYAROVA CT without contrast enhancement : -Calcareous stones of the gallbladder have a greater density compared to bile -Pure cholesterol stones have a lower density; There is an inverse relationship between cholesterol levels and X-ray attenuation: -May have the same density as bile and not be detected on CT -The central part of the stone may contain nitrogen gas: a symptom of the Mercedes-Benz
  • 13. 13 KazNMU named after . S.D.ASFENDIYAROVA On an axial computed tomogram without contrast, a cluster of layered and faceted stones is determined in the gallbladder .
  • 14. 14 KazNMU named after . S.D.ASFENDIYAROVA In a patient with acute calculous cholecystitis on the axial A computed tomogram with contrast shows thickening of the gallbladder wall and calcified stones.
  • 15. 15 KazNMU named after . S.D.ASFENDIYAROVA ABDOMEB CT WITH CONTRAST The patient's sagittal computed tomogram and 3D reconstruction reveal a large calcified calculus.
  • 16. 16 KazNMU named after . S.D.ASFENDIYAROVA MRI FOR GALLBLADDER STONES T1 – pigmented stones ( hyperintense ) - cholesterol stones ( hypointense ) • T2-VI: A small focus of absent or weak signal limited to highly echogenic bile within the gallbladder • MRcholangiopancreatography : Round lesions of absence of intragallbladder
  • 17. 17 KazNMU named after . S.D.ASFENDIYAROVA Axial T2 HASTE in a slightly thickened gallbladder, multiple stones giving a weak signal are determined.
  • 18. 18 KazNMU named after . S.D.ASFENDIYAROVA Small area of absent or weak signal limited to highly echogenic bile, inside the gallbladder
  • 19. 19 KazNMU named after . S.D.ASFENDIYAROVA MR tomograms in the axial and frontal planes. Cholelithiasis. Gallstones in the gallbladder cavity are characterized by a lack of signal within the gallbladder on T2-VI and STIR
  • 20. 20 KazNMU named after . S.D.ASFENDIYAROVA Endoscopic retrograde cholangiopancreatography Mobile filling defects inside Contrast-filled gallbladder blisters and stones in the extrahepatic bile ducts ERCP sensitivity 68 - 93% tubular stenosis of the common bile duct with reflux of contrast into the main hepatic duct against the background of cholelithiasis expansion of the pancreatic duct and branches of the 2nd and 3rd order, uneven contours of the duct and branches
  • 21. 21 KazNMU named after . S.D.ASFENDIYAROVA Forforan gallbladder General characteristics: • Best diagnostic criterion: o Calcification in the form of a curved “rim” in the right hypochondrium, resembling the shape of a gallbladder • Morphology: Two options: - Limited mucosal calcification: high risk of malignancy - Diffuse wall calcification: low risk of malignancy
  • 22. 22 KazNMU named after . S.D.ASFENDIYAROVA DIFFERENTIAL DIAGNOSTICS Gallbladder polyp Bladder bile sludge Gallbladder carcinoma Focal adenomyomatosis Parasitic infestation of the gallbladder Intestinal gases Emphysematous cholecystitis
  • 23. 23 KazNMU named after . S.D.ASFENDIYAROVA VISUALIZATION GUIDELINES: Ultrasound is the best imaging modality for evaluating patients with upper abdominal pain/discomfort. ➢When evaluating patients with pain/discomfort in the upper right quadrant of the abdomen after a fatty meal, especially middle-aged obese women , remember the likely presence of cholelithiasis ➢Tips for interpreting images: the acoustic shadow they cast is of great importance - Stones that do not cast a shadow can be mistaken for other formations of the gallbladder, for example, polyp, sludge , carcinoma - Shrinking, stone-filled gallbladder: assess for wall-echo-shadow sign or examine interlobar fissure
  • 24. Thank you for attention! ​Mr. Almaty, st. Tole bi, 94 +7 727 338 70 90 www.kaznmu.kz kaznmu@kaznmu.kz KAZAKH NATIONAL MEDICAL UNIVERSITY NAMED AFTER S.D. ASFENDYAROVA ​@ kaznmu https:// www.facebook.com/KazNMU https://www.youtube.com/kaznmu _