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International Journal of Trend in Scientific Research and Development (IJTSRD)
Volume 7 Issue 6, November-December 2023 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470
@ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 21
Ayurvedic Management of ADHD - A Case Study
Dr. Tikina Padhan1, Dr. Susmita Panda2, Dr. Sangita Prusty3
1,2
MD Scholar, P.G. Department of Kaumarabhritya, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
3
HOD & Reader, P.G. Department of Kaumarabhritya, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India
ABSTRACT
INTRODUCTION: Attention-deficit hyperactivity disorder is the
commonest neurobehavioral or neurodevelopmental disorder of
childhood characterized by persistent hyperactivity, impulsivity and
inattention that significantly impairs educational achievement and
social functioning. In Ayurveda there is no direct reference for
ADHD but some references about abnormal behavior it can be
considered under Unmada i.e. Manashika Vikara.
AIM and OBJECTIVE: To access the efficacy of Ayurvedic drugs
and therapy treatment in the management of ADHD in children.
SETTING: Kaumarabhritya OPD & IPD, Gopabandhu Ayurveda
Mahavidyalaya, Puri.
METHOD: A 7 years old male child comes to OPD of
Kaumarabhritya Department having complains of running to bite,
climbing tree and fighting with others, anger, making careless
mistakes in homework, inability to memories little things in
schoolwork, not listening to anyone, improper speech was advised to
admit in IPD for treatment. The Patient was advised for Deepana-
Pachana, Samsamana, Medhya drugs and in therapies Siroabhyanga,
Siropichu and Matravasti.
RESULT: After treatment of 3 months, the patient had shown
remarkable changes like not running to bite, occasionally climbing
tree, occasionally fighting with other, trying to focus in schoolwork,
responding to others up to some extends.
How to cite this paper: Dr. Tikina
Padhan | Dr. Susmita Panda | Dr. Sangita
Prusty "Ayurvedic Management of
ADHD - A Case Study" Published in
International
Journal of Trend in
Scientific Research
and Development
(ijtsrd), ISSN:
2456-6470,
Volume-7 | Issue-6,
December 2023,
pp.21-24, URL:
www.ijtsrd.com/papers/ijtsrd60095.pdf
Copyright © 2023 by author (s) and
International Journal of Trend in
Scientific Research and Development
Journal. This is an
Open Access article
distributed under the
terms of the Creative Commons
Attribution License (CC BY 4.0)
(http://creativecommons.org/licenses/by/4.0)
KEYWORDS: ADHD, Deepana-
Pachana, Samsamana, Medhya,
Siroabhyanga, Siropichu, Matravasti
INTRODUCTION
Attention deficit hyperactivity disorder (ADHD) is
the most common neurobehavioral disorder in
childhood, among the most prevalent chronic health
conditions affecting, and one of the most extensively
studied neurodevelopmental disorders of childhood.
ADHD is characterized by inattention, including
increased distractibility and difficulty sustaining
attention; poor impulse control and decreased self-
inhibitory capacity; and motor over activity and
motor restlessness1
. Data indicates that 8-12% of
school-going children have ADHD in western
countries, but there is no data available from India2
. It
is 3 times commoner in boys3
.
Risk factors in children with untreated ADHD as they
become adults include engaging in risk-taking
behaviours, employment difficulties and relationship
difficulties. It may leads to violence, crime, accidents,
health risk, suicide and become the pathway to
premature death.
The present case was carried out in Kaumarabhritya
OPD with an aim to assess the efficacy of Ayurvedic
treatment protocol in the management of ADHD in
children.
ETIOPATHOGENESIS2
Recent functional MRI brain studies indicate that the
disorder may be caused by atypical functioning in the
frontal lobes, basal ganglia, corpus callosum and
cerebral vermis.
Family studies have provided strong evidence that
genetics plays a major role in conferring
susceptibility to ADHD.
Studies have indicated that low birth weight and
psychosocial adversity are predisposing risk factors
for ADHD.
IJTSRD60095
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 22
DIAGNOSIS-DSM-V CRITERIA2
HYPERACTIVITY IMPULSIVITY (9 Criteria)
Fidgets with hands or feet or squirms in seat
Leaves seat when should be seated
Runs about or climbs excessively and inappropriately
Cannot play or engage in leisure activities quietly
Always ‘on the go’ or ‘driven by a motor’
Talks excessively
Blurts out answer before question is completed
Has difficulty awaiting turn
Interrupts or intrudes others’ conversation or games
INATTENTION (9 Criteria)
Careless with detail
Fails to sustain attention in tasks
Appears not to listen
Does not finish instructed tasks
Poor in organizing tasks
Avoids tasks that require sustained mental effort
Loose things
Easily distracted by extraneous stimuli
Forgetful in daily activities
CASE REPORT
Patient’s Description
A 7-year-old male child with complaints of -
 Hyperactivity like – Running and climbing tree
excessively
Run to bite and fighting with others
 Making careless mistakes in homework
 Inability to memories little things in school-
works
 Not listening to anyone
 Improper speech had approached our Hospital.
HISTORY OF PRESENT ILLNESS
Before 2 years, the patient was apparently ok. Then
during covid period, when stayed in home gradually
he developed these sign and symptoms.
BIRTH HISTORY
 PERI NATAL- Mother age-36 year
 NATAL- Term-CS – Birth wt.-2.9kg, no history
of Birth asphyxia
 POST NATAL- NAD
PERSONAL HISTORY
 Diet- Mixed
 Bowel-Clear
 Urine-Normal
 Sleep-Disturbed
IMMUNIZATION HISTORY
Properly done as per NIS
TREATMENT
The patient was taking treatment in Department of
kaumarabhritya for 3 months.
TREATMENT PLAN-T1
Line of Treatment No. of Days Medication Used
Deepana-Pachana 30 days Saraswatarista
Medhya 30 days
Bramhi vati
Smritisagara rasa
Syp. Mentat
Siro abhyanga 30 days Mahanarayana Taila
TREATMENT PLAN-T2
Line of Treatment No. Of Days Medication Used
Samshamana 30 days Kumarakalyana rasa
Medhya 30 days
Bramhi vati
Smritisagara rasa
Syp.Mentat
Syp.Medhya rasayana
Siropichu
Talam
12 days
Mahanarayana Taila
Rasnadi churna
Matra vasti 12 days Mahanarayana Taila & Eranda Taila
Kaphahara (due to complain of kasa) 7 days
Siddhamakaradhwaja rasa
Laxmivilash rasa
Talisadi churna
Byaghri haritaki
TREATMENT PLAN-T3
Line of Treatment No. Of Days Medication Used
Siropichu 12 days Mahanarayana Taila
Matravasti 12 days Mahanarayana Taila & Eranda Taila
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 23
OBSERVATION & RESULT
BEFORE TREATMENT
 Forgetful in daily activities
 Easily distracted by extraneous stimuli
 Poor in organizing tasks
 Loses things
 Poor school performance
 Careless mistakes in homework
 Often does not seem to listen when spoken to
directly
 Not sitting in one place constantly at least for 5
minutes
 Leaves seat in classroom
 Runs and climbs excessively
 Bites and fights with others
 Difficulty in playing or engaging in leisure
activities
 Careless mistakes in homework
 Poor school performance
 Not listening to anyone
 Improper speech, Disturb sleep
AFTER TREATMENT
 Occasionally forgot
 Distracted by stimuli
 Organizing in task increase
 Losing things decrease
 Improvement in school performance
 Less mistakes in homework
 Responds to others
 Sits for 5-10 minutes in a place
 Sometimes leave classroom
 Not climbing but in running no changes
 Not biting but in fighting no changes
 Focus on playing in leisure time increase
 Often make mistakes
 Improvement in school performance
 Now respond to others
 Improvement in speech, Sound sleep
DISCUSSION
ADHD cannot be compared directly to any vyadhis of
Ayurveda. But we can compare like, it occurs due to
vitiation of Dhee (rational thinking), Dhriti
(intellectual power of mind) and Smriti (memory) by
vitiated Vata. That affects Manoarthas and
Manokarma which results into improper contact of
the sense with their objectives and give rise to
inattention, hyperactivity, impulsivity4
.
So the main method of treatment is to bring back
Prakupita vata to normal state, increase intellectual
power and maintenance of agni.
Ayurvedic therapies that will treat vata both in the
mind, nervous system and cleanse ama were
administered to patient. Treatment includes Agni
deepana, Vata shamana and Medhya rasayana.
Bramhi vati – Used in mastiska and hridaya
dourbalya, buddhi pranja swarapittada, rasayani5
.
Saraswatarista – Ayuvirya smruti medha bala kanti
vibardhayet, vaksudhhikara, hridya 6
.
Kumarakalyana rasa- improves immunity, cures all
disease of children7
Siropichu – Promotes strengths to siro-kapala and
helps in indriya prasad8
. The drug Mahanarayana
taila have sheeta virya and pittahara properties which
gives a cooling effect to the head, constrict the local
blood vessels, by which increase in blood flow to
brain during hyperactivity, inattention and impulsivity
reduce and induce sound sleep9
.
Vasti – a purification process by which all vitiated
doshas are expelled from anal route and especially
vata is pacified. Vasti dravya may activate the neuro-
humeral transmission by stimulating the gut – brain,
regulating changes in behaviour and emotions. Hence,
Vasti has been planned with Mahanarayana taila that
can be used in all therapies both externally and
internally in sakhasrita -kosthasrita vata, pacifies all
types of vata vikara10
.
CONCLUSION
According to Ayurveda, ADHD can be nearly co-
related to Unmada based on the sign and symptoms.
On the basis of the case was diagnosed as Vata-
Pittaja Unmada and accordingly treatment was given-
Deepana, Pachana, Shiropichu,Matravasti followed
by Shaman Aushadhi with Medhya drugs. By our
Ayurvedic management, we can challenge the disease
ADHD. It may be for some extend to make child
streamline in social activities and make it a social
well-being to make familiar atmosphere in home and
also reduce hazards to bring our country in new light.
References
[1] Kliegman, St Geme, Blum, Shah, Tasker,
Wilson. Nelson Textbook of Pediatrics. s.l. :
Elsevier, 2020, p.262.
[2] A Parthsarathy, IAP Textbook of Pediatrics,
Jaypee Brothers Medical Publishers, New
Delhi, 7th
Edition, p.542.
[3] OP Ghai, Vinod K Paul, Arvind Bagga. Ghai
Essential pediatrics, CBS Publishers and
distributors, New Delhi, 7th
edition, p.38.
[4] Bramhanand Tripathi. Charaka Samhita, Vol-2,
Chikitsa Sthana, Chapter no-9, Shloka no.-6,
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2015, p. 376.
[5] Prof. Siddhinandan Mishra, Bhaisajya
Ratnavali, Chapter-5, Shloka no-151,
International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470
@ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 24
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2017, p. 173.
[6] Prof. Siddhinandan Mishra, Bhaisajya
Ratnavali, Chapter-73, Shloka no-192,
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2017, p. 173.
[7] Prof. Siddhinandan Mishra, Bhaisajya
Ratnavali, Chapter-71, Shloka no-118-119,
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2017, p. 1088.
[8] Pt. Kasinatha Sastri, Dr. Gorakhanatha
Chaturvedi, Charaka Samhita, Elaborated
Vidyotini Hindi Commentary, Part-1, Sutra
Sthana, Chapter-5, Shloka no-83, Chaukhamba
Bharati Academy, Varanasi, Reprint 2018,
p.127.
[9] Prof. Siddhinandan Mishra, Bhaisajya
Ratnavali, Chapter-26, Shloka no-325-336,
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2017, p. 547.
[10] Bramhanand Tripathi. Charaka Samhita, Vol-2,
Siddhi Sthana, Chapter no-4, Shloka no.-53,
Chaukhamba Surabharati Prakashan, Varanasi,
Edition 2015, p. 376.

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Ayurvedic Management of ADHD A Case Study

  • 1. International Journal of Trend in Scientific Research and Development (IJTSRD) Volume 7 Issue 6, November-December 2023 Available Online: www.ijtsrd.com e-ISSN: 2456 – 6470 @ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 21 Ayurvedic Management of ADHD - A Case Study Dr. Tikina Padhan1, Dr. Susmita Panda2, Dr. Sangita Prusty3 1,2 MD Scholar, P.G. Department of Kaumarabhritya, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India 3 HOD & Reader, P.G. Department of Kaumarabhritya, Gopabandhu Ayurveda Mahavidyalaya, Puri, Odisha, India ABSTRACT INTRODUCTION: Attention-deficit hyperactivity disorder is the commonest neurobehavioral or neurodevelopmental disorder of childhood characterized by persistent hyperactivity, impulsivity and inattention that significantly impairs educational achievement and social functioning. In Ayurveda there is no direct reference for ADHD but some references about abnormal behavior it can be considered under Unmada i.e. Manashika Vikara. AIM and OBJECTIVE: To access the efficacy of Ayurvedic drugs and therapy treatment in the management of ADHD in children. SETTING: Kaumarabhritya OPD & IPD, Gopabandhu Ayurveda Mahavidyalaya, Puri. METHOD: A 7 years old male child comes to OPD of Kaumarabhritya Department having complains of running to bite, climbing tree and fighting with others, anger, making careless mistakes in homework, inability to memories little things in schoolwork, not listening to anyone, improper speech was advised to admit in IPD for treatment. The Patient was advised for Deepana- Pachana, Samsamana, Medhya drugs and in therapies Siroabhyanga, Siropichu and Matravasti. RESULT: After treatment of 3 months, the patient had shown remarkable changes like not running to bite, occasionally climbing tree, occasionally fighting with other, trying to focus in schoolwork, responding to others up to some extends. How to cite this paper: Dr. Tikina Padhan | Dr. Susmita Panda | Dr. Sangita Prusty "Ayurvedic Management of ADHD - A Case Study" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-6, December 2023, pp.21-24, URL: www.ijtsrd.com/papers/ijtsrd60095.pdf Copyright © 2023 by author (s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0) KEYWORDS: ADHD, Deepana- Pachana, Samsamana, Medhya, Siroabhyanga, Siropichu, Matravasti INTRODUCTION Attention deficit hyperactivity disorder (ADHD) is the most common neurobehavioral disorder in childhood, among the most prevalent chronic health conditions affecting, and one of the most extensively studied neurodevelopmental disorders of childhood. ADHD is characterized by inattention, including increased distractibility and difficulty sustaining attention; poor impulse control and decreased self- inhibitory capacity; and motor over activity and motor restlessness1 . Data indicates that 8-12% of school-going children have ADHD in western countries, but there is no data available from India2 . It is 3 times commoner in boys3 . Risk factors in children with untreated ADHD as they become adults include engaging in risk-taking behaviours, employment difficulties and relationship difficulties. It may leads to violence, crime, accidents, health risk, suicide and become the pathway to premature death. The present case was carried out in Kaumarabhritya OPD with an aim to assess the efficacy of Ayurvedic treatment protocol in the management of ADHD in children. ETIOPATHOGENESIS2 Recent functional MRI brain studies indicate that the disorder may be caused by atypical functioning in the frontal lobes, basal ganglia, corpus callosum and cerebral vermis. Family studies have provided strong evidence that genetics plays a major role in conferring susceptibility to ADHD. Studies have indicated that low birth weight and psychosocial adversity are predisposing risk factors for ADHD. IJTSRD60095
  • 2. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 22 DIAGNOSIS-DSM-V CRITERIA2 HYPERACTIVITY IMPULSIVITY (9 Criteria) Fidgets with hands or feet or squirms in seat Leaves seat when should be seated Runs about or climbs excessively and inappropriately Cannot play or engage in leisure activities quietly Always ‘on the go’ or ‘driven by a motor’ Talks excessively Blurts out answer before question is completed Has difficulty awaiting turn Interrupts or intrudes others’ conversation or games INATTENTION (9 Criteria) Careless with detail Fails to sustain attention in tasks Appears not to listen Does not finish instructed tasks Poor in organizing tasks Avoids tasks that require sustained mental effort Loose things Easily distracted by extraneous stimuli Forgetful in daily activities CASE REPORT Patient’s Description A 7-year-old male child with complaints of -  Hyperactivity like – Running and climbing tree excessively Run to bite and fighting with others  Making careless mistakes in homework  Inability to memories little things in school- works  Not listening to anyone  Improper speech had approached our Hospital. HISTORY OF PRESENT ILLNESS Before 2 years, the patient was apparently ok. Then during covid period, when stayed in home gradually he developed these sign and symptoms. BIRTH HISTORY  PERI NATAL- Mother age-36 year  NATAL- Term-CS – Birth wt.-2.9kg, no history of Birth asphyxia  POST NATAL- NAD PERSONAL HISTORY  Diet- Mixed  Bowel-Clear  Urine-Normal  Sleep-Disturbed IMMUNIZATION HISTORY Properly done as per NIS TREATMENT The patient was taking treatment in Department of kaumarabhritya for 3 months. TREATMENT PLAN-T1 Line of Treatment No. of Days Medication Used Deepana-Pachana 30 days Saraswatarista Medhya 30 days Bramhi vati Smritisagara rasa Syp. Mentat Siro abhyanga 30 days Mahanarayana Taila TREATMENT PLAN-T2 Line of Treatment No. Of Days Medication Used Samshamana 30 days Kumarakalyana rasa Medhya 30 days Bramhi vati Smritisagara rasa Syp.Mentat Syp.Medhya rasayana Siropichu Talam 12 days Mahanarayana Taila Rasnadi churna Matra vasti 12 days Mahanarayana Taila & Eranda Taila Kaphahara (due to complain of kasa) 7 days Siddhamakaradhwaja rasa Laxmivilash rasa Talisadi churna Byaghri haritaki TREATMENT PLAN-T3 Line of Treatment No. Of Days Medication Used Siropichu 12 days Mahanarayana Taila Matravasti 12 days Mahanarayana Taila & Eranda Taila
  • 3. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 23 OBSERVATION & RESULT BEFORE TREATMENT  Forgetful in daily activities  Easily distracted by extraneous stimuli  Poor in organizing tasks  Loses things  Poor school performance  Careless mistakes in homework  Often does not seem to listen when spoken to directly  Not sitting in one place constantly at least for 5 minutes  Leaves seat in classroom  Runs and climbs excessively  Bites and fights with others  Difficulty in playing or engaging in leisure activities  Careless mistakes in homework  Poor school performance  Not listening to anyone  Improper speech, Disturb sleep AFTER TREATMENT  Occasionally forgot  Distracted by stimuli  Organizing in task increase  Losing things decrease  Improvement in school performance  Less mistakes in homework  Responds to others  Sits for 5-10 minutes in a place  Sometimes leave classroom  Not climbing but in running no changes  Not biting but in fighting no changes  Focus on playing in leisure time increase  Often make mistakes  Improvement in school performance  Now respond to others  Improvement in speech, Sound sleep DISCUSSION ADHD cannot be compared directly to any vyadhis of Ayurveda. But we can compare like, it occurs due to vitiation of Dhee (rational thinking), Dhriti (intellectual power of mind) and Smriti (memory) by vitiated Vata. That affects Manoarthas and Manokarma which results into improper contact of the sense with their objectives and give rise to inattention, hyperactivity, impulsivity4 . So the main method of treatment is to bring back Prakupita vata to normal state, increase intellectual power and maintenance of agni. Ayurvedic therapies that will treat vata both in the mind, nervous system and cleanse ama were administered to patient. Treatment includes Agni deepana, Vata shamana and Medhya rasayana. Bramhi vati – Used in mastiska and hridaya dourbalya, buddhi pranja swarapittada, rasayani5 . Saraswatarista – Ayuvirya smruti medha bala kanti vibardhayet, vaksudhhikara, hridya 6 . Kumarakalyana rasa- improves immunity, cures all disease of children7 Siropichu – Promotes strengths to siro-kapala and helps in indriya prasad8 . The drug Mahanarayana taila have sheeta virya and pittahara properties which gives a cooling effect to the head, constrict the local blood vessels, by which increase in blood flow to brain during hyperactivity, inattention and impulsivity reduce and induce sound sleep9 . Vasti – a purification process by which all vitiated doshas are expelled from anal route and especially vata is pacified. Vasti dravya may activate the neuro- humeral transmission by stimulating the gut – brain, regulating changes in behaviour and emotions. Hence, Vasti has been planned with Mahanarayana taila that can be used in all therapies both externally and internally in sakhasrita -kosthasrita vata, pacifies all types of vata vikara10 . CONCLUSION According to Ayurveda, ADHD can be nearly co- related to Unmada based on the sign and symptoms. On the basis of the case was diagnosed as Vata- Pittaja Unmada and accordingly treatment was given- Deepana, Pachana, Shiropichu,Matravasti followed by Shaman Aushadhi with Medhya drugs. By our Ayurvedic management, we can challenge the disease ADHD. It may be for some extend to make child streamline in social activities and make it a social well-being to make familiar atmosphere in home and also reduce hazards to bring our country in new light. References [1] Kliegman, St Geme, Blum, Shah, Tasker, Wilson. Nelson Textbook of Pediatrics. s.l. : Elsevier, 2020, p.262. [2] A Parthsarathy, IAP Textbook of Pediatrics, Jaypee Brothers Medical Publishers, New Delhi, 7th Edition, p.542. [3] OP Ghai, Vinod K Paul, Arvind Bagga. Ghai Essential pediatrics, CBS Publishers and distributors, New Delhi, 7th edition, p.38. [4] Bramhanand Tripathi. Charaka Samhita, Vol-2, Chikitsa Sthana, Chapter no-9, Shloka no.-6, Chaukhamba Surabharati Prakashan, Varanasi, Edition 2015, p. 376. [5] Prof. Siddhinandan Mishra, Bhaisajya Ratnavali, Chapter-5, Shloka no-151,
  • 4. International Journal of Trend in Scientific Research and Development @ www.ijtsrd.com eISSN: 2456-6470 @ IJTSRD | Unique Paper ID – IJTSRD60095 | Volume – 7 | Issue – 6 | Nov-Dec 2023 Page 24 Chaukhamba Surabharati Prakashan, Varanasi, Edition 2017, p. 173. [6] Prof. Siddhinandan Mishra, Bhaisajya Ratnavali, Chapter-73, Shloka no-192, Chaukhamba Surabharati Prakashan, Varanasi, Edition 2017, p. 173. [7] Prof. Siddhinandan Mishra, Bhaisajya Ratnavali, Chapter-71, Shloka no-118-119, Chaukhamba Surabharati Prakashan, Varanasi, Edition 2017, p. 1088. [8] Pt. Kasinatha Sastri, Dr. Gorakhanatha Chaturvedi, Charaka Samhita, Elaborated Vidyotini Hindi Commentary, Part-1, Sutra Sthana, Chapter-5, Shloka no-83, Chaukhamba Bharati Academy, Varanasi, Reprint 2018, p.127. [9] Prof. Siddhinandan Mishra, Bhaisajya Ratnavali, Chapter-26, Shloka no-325-336, Chaukhamba Surabharati Prakashan, Varanasi, Edition 2017, p. 547. [10] Bramhanand Tripathi. Charaka Samhita, Vol-2, Siddhi Sthana, Chapter no-4, Shloka no.-53, Chaukhamba Surabharati Prakashan, Varanasi, Edition 2015, p. 376.