THERE IS a strong relation and bidirectional relation between oral health state and systemic health .chronic microbial diseases like periodontitis contrbute into bacteremia which play a major role in propagate an inflamatory casacade of event that is finalise by resultant systemic diseases. Most systemic diseases have oral manifestation and viceversa.

1. Oral Health as a public health
indicator
Marina Sameh
Yassmen Hesham
Zead Hossam
Muhanad Ehab Rady
Under Supervision
Dr. Shimaa Hussein

2. Mouth is a mirror of the internal
secrets of systemic health
Sample Footer Text
2

3. Oral Health An integral part of general
health and well-being
1/2/2024
Sample Footer Text
3

4. Oral cavity
Is intersection of medicine and dentistry.
Is a window into the general health of a
patient.
1/2/2024
Sample Footer Text
4

5. Importance of Oral Health
oral health and general health should not
be interpreted as a separate entities.
Oral health means more than a healthy
teeth.
No one can be healthy without oral health
1/2/2024
Sample Footer Text
5

6. What happens if oral health problems
are ignored?
pain and suffering
Devastating health complications , with
financial and social costs
Diminish the quality of life and burdens
society
1/2/2024
Sample Footer Text
6

7. Oral Diseases
 is a “Silent epidemic” condition .
Affect all populations:
Children
Elderly
No gender difference (male like female)
1/2/2024
Sample Footer Text
7

8. Oral health means much more
than healthy teeth
It means free from :
chronic oral-facial pain conditions
oral and pharyngeal diseases
oral soft tissue lesions
birth defects such as cleft lip and palate.oral, dental, and
craniofacial tissues (craniofacial complex)
1/2/2024
Sample Footer Text
8

9. The mouth is a mirror of
systemic health
 A thorough oral examination can detect:
signs of nutritional deficiencies
microbial infections
immune disorders
injuries
some cancer
1/2/2024
Sample Footer Text
9

10. What is the relationship between oral health
and general health and well-being?
1/2/2024
Sample Footer Text
10

11. What is the relationship between oral health
and general health and well-being?
 Many systemic diseases have initial signs of
oral manifestations.
 Oral cavity is a portal of entry of microbial
disease infections that affect general health
state.
 Oral cavity adversely affected by
pharmaceuticals therapies used for treating
systemic conditions. 1/2/2024
Sample Footer Text
11

12. Oral and craniofacial diseases contribute to :
 compromised ability to
bite, chew and swallow
foods.
 limitations in food
selection.
 poor nutrition.
1/2/2024
Sample Footer Text
12

13. Oral manifestations of systemic disease
 Periodontal diseases
 ORAL ULCERS
 Xerostomia
 Root caries
 Allergy and Mucosal changes due to drug therapy
 Benign soft tissue lesions and keratotic lesions, chiefly local
 Retarded eruption
 Psychic disorders
1/2/2024
Sample Footer Text
13

14. Separate Medical/Dental Education Systems
Medical Education System
does not help put oral health
on phyisician’s Radars!
1/2/2024
Sample Footer Text
14

15. Mechanisms that mediate the connection
between oral and systemic health
 Gene polymorphisms
 Environmental factors (stress, habits—such as
smoking and high‐fat diets/consumption of highly
processed foods)
 Medications
 Microbial dysbiosis that altered host immune
response. 1/2/2024
Sample Footer Text
15

16. Microbial dysbiosis
More than 400 species
of bacteria create an
exquisite microbial
ecological system in
the form of a biofilm
1/2/2024
Sample Footer Text
16

17. Oral infections
17
Sample Footer Text 1/2/2024
periodontal
diseases :
are the most
common chronic
microbial diseases
in the world.

18. Gingival and periodontal diseases
 is the most widespread
chronic inflammatory
response to oral
microbes’
1/2/2024
Sample Footer Text
18

19. Role of Oral biofilm in systemic diseases
1/2/2024
Sample Footer Text
19

20. Microbial Dysbiosis Pathogenesis
periodontal disease is a chronic
microbial, inflammatory
progressive disease.
Initiated by bacterial biofilm.
1/2/2024
Sample Footer Text
20

21. How Oral Microbes Cause Systemic
Disease?
Oral – infection – associated
bacteremias can contributes
to the risk of acute events.
1/2/2024
Sample Footer Text
21

22. The Emerging Connection between Oral
infection & Systemic diseases
1/2/2024
Sample Footer Text
22

23. Pathogenesis
Direct
Byproduct
bacteria
Endotoxins
into blood
circulation
Indirect
Inflamatory
mediators
IL
,
PG2
&MMP
1/2/2024
Sample Footer Text
23

24. Oral infections are associated with a number of
systemic diseases and disorders
 Bidirection relation between periodontal
disease and :
 Heart diseases
 Diabetes mellitus
 H,pylori
 respiratory diseases
 Preterm baby
 other diseases in immunocompromised
patients especially those with cancer.
1/2/2024
Sample Footer Text
24

25. There is a strong association between
periodontitis and ……
1/2/2024
Sample Footer Text
25

26. The effects of oral Disease
on Systemic Disease
• The periodontium serve as a
reservoir of bacteria, bacterial
products, inflammation and
immune mediators.
• These factors can interact with
other organ systems remote from
the oral cavity.
1/2/2024
Sample Footer Text
26

27. Oral manifestation of Cardiovascular
diseases
 Periodontal Diseases
 Lichenoid reaction (medication
used)
 Xerostomia
 Gingival hyperplasia
 Haemorrgic complication
1/2/2024
Sample Footer Text
27

28. Oral manifestation of Renal diseases
 Oral ulcer
 Uremic stomatitis
 Burning sensation
 Gingival hyperplasia (cyclosporin )
 Candidal infection
 Xerostomia
1/2/2024
Sample Footer Text
28

29. Radiographic image of
Hyperparathyroidism
-Bone has “ground
glass appearance”
-Multilocular
radiolucency
1/2/2024
Sample Footer Text
29

30. Oral Manifestation of Respiratory
Diseases
Xerostomia
Candidal infection
Chronic sinusitis
infection
Mouth breathing
1/2/2024
Sample Footer Text
30

31. Oral manifestation of Diabetes Mellitus
 Periodontal Abscess
 Xerostomia
 poor wound healing
 Gingival recession
 Cervical /root caries
 Sialosis
 Candidal infection
 Lichenoid reaction
1/2/2024
Sample Footer Text
31

32. Oral manifestation of Diabetes Mellitus
(Burning Mouth syndrome )
1/2/2024
Sample Footer Text
32

33. Oral Manifestation of Gastrointestinal
diseases
Gastrointestinal reflux ( Erosion
)
Ulcerative colitis (ulcers)
Crhons diseases ( mucosal tags
,ulcers , swollen lips)
Petuz jeghers syndrome (mucosal
pigmentation & intestinal polyps) 1/2/2024
Sample Footer Text
33

34. Blood Disorder
Chronic lymphocytic leukemia: severe gingival
enlargement
1/2/2024
Sample Footer Text
34

35. Blood Disorder
 Acute myelocytic leukemia: marked gingival enlargement
1/2/2024
Sample Footer Text
35

36. Severe necrotizing gingivitis in a 32-year-old
HIV sero-positive homosexual man
1/2/2024
Sample Footer Text
36

37. Hyperplastic gingivitis
1/2/2024
Sample Footer Text
37

38. Fibrous gingival hyperplasia caused by
phenytoin (medication )
1/2/2024
Sample Footer Text
38

39. Gingival hyperplasia caused by cyclosporine
1/2/2024
Sample Footer Text
39

40. Gingival fibromatosis
1/2/2024
Sample Footer Text
40

41. Severe gingivitis during pregnancy
1/2/2024
Sample Footer Text
41

42. Pyogenic granuloma of the gingiva
1/2/2024
Sample Footer Text
42

43. Herpes zoster: clusters of vesicles on the
palate.
1/2/2024
Sample Footer Text
43

44. Conclusions
44
1/2/2024
One should never underestimate oral
disorders as always curable.
People should take utmost care of the
oral condition seriously to prevent
significant complications.
Dental health should never be considered
a distinct, remote, and lower significant
part from general health
Oral health affects overall health

45. References
 Makkar, H.; Reynolds, M.A.; Wadhawan, A.; Dagdag, A.;
Merchant, A.T.; Postolache, T.T. Periodontal, metabolic, and
cardiovascular disease: Exploring the role of inflammation and
mental health. Pteridines 2018, 29, 124–163
 FDI World Dental Federation. Global periodontal health. Int.
Dent. J. 2019.
 Botelho, J., Mascarenhas, P., Viana, J. et al. An umbrella review
of the evidence linking oral health and systemic
noncommunicable diseases. Nat Commun (2022); 13, 7614.
1/2/2024
Sample Footer Text
45

46. 46
Sample Footer Text
Thank you