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Asymptomatic Bacteriuria
Defination
 When a bacterial count of same species over
10^5 per ml in mild stream clean catch
specimen of urine on two occasion is
detected without the symptom of urinary
infection it is called asymptomatic
bacteriuria
 Causes
 Asymptomatic bacteriuria occurs in a small
number of healthy individuals. It more often
affects women than men. The reasons for the
lack of symptoms are not well understood.
 Most patients with asymptomatic bacteriuria
do not need treatment because the bacteria are
not causing any harm. Persons who have
urinary catheters often will have
bacteriuria, but most will not have symptoms.
 The following increases your risk:
 Diabetes
 Infected kidney stones
 Kidney transplant
 Older age
 Pregnancy -- up to 40% of pregnant women
with untreated asymptomatic bacteriuria will
develop a kidney infection
 Vesicoureteral reflux in young children
Symptoms
 By definition, asymptomatic bacteriuria
causes no symptoms. The symptoms of a
urinary tract infection include burning
during urination, an increased urgency to
urinate, and increased frequency of
urination.
Exams and Tests
 Asymptomatic bacteriuria is detected by the
discovery of significant bacterial growth in
a urine culture taken from a urine sample.
Treatment
 Pregnant women, kidney transplant
recipients, children with vesicoureteral
reflux, and those with infected kidney stones
are more likely to be given antibiotics.
 Giving antibiotics to persons who have long-
term urinary catheters in place may cause
additional problems. The bacteria may be more
difficult to treat and the patients may develop a
yeast infection.
 If asymptomatic bacteriuria is found before
a urinary tract procedure, it should be
treated to prevent complications. The course
of treatment in these cases depends on the
person's risk factors.
Possible Complications
 Untreated, asymptomatic bacteriuria can
lead to a kidney infection in high-risk
individuals
When to Contact a Medical
Professional
 Call your health care provider if the
following symptoms occur:
 Difficulty emptying your bladder
 Fever
 Flank or back pain
 Pain with urination
PROTEINURIA
INPREGNANCY
 When 2+protein in deepstick test it is
called proteinuria
 CAUSES
 Pre-eclampsia and eclampsia
 Urinary tract infection
 Chronic Renal disease :Nephritis and
Nephrotic Syndrome
 Essential hypertension
 Orthostatic- Due to increased lumbar
lordosis there is increased pressure on the
inferior Venacava by the uterus or left renal
vein
 Is compressed by the aorta this leads to
congestion of one or both kidney leading to
proteinuria.
 In late pregnancy,the enlarged gravid
utrerus may compress es the left renal vein
when the patient is lying on supine position
.lying down on lateral position relieves the
pressure and congestion and makes the
urine free of protein
 Investigations (microscopic examination of
Pus cells RBCs Cast cells)
 Management depends upon etiology
Hematuria in Pregnancy
 Painful - infection
 Painless – neoplastic, hyperplastic, vascular
 Gross – urine appears ―RED‖; lower tract
prob.
 Microscopic – > 5 RBC’s/hpf; kidney dz
 False hematuria = urine appears bloody, but
dipstick results are neg. for blood and no
RBC’s on micro
Free hgb, myoglobin, porphyrins
1.Physological—menstruation
2. Infection—Pyelonephriitis , cystitis ,
urethritis , Tuberculosis of kidney and
bladder
3. Trauma– Renal injury, Foreign body in
bladder and urethra including catheter.
4.Inflammatory / autoimmune—
Glomerulonephritis , Polyarteritis nodosa ,
Ch. Interstitial nephritis, radiatinal
inflammation of renal tract.
5.Accidental haemorrhage
6.Rupture uterus
7. Obstructed labour
8 .DIC
9. Traumatic PPH
10.Heparine therapy for DVT
11.Eclampsia
12. HellP syndrome
13. Mismatched blood transfusion
14.Pregnancy associated with hematological
diseases
15.Drug induced
16. Instrumental delivery
17.Traumatic VVF
5.Stones– renal , ureteric , bladder and
urethra.
6 .Tumors– benign /malignant of renal tract.
7.General—drugs including anticoagulants
Bleeding disorders , caruncle and prolapse
of urethral mucosa.
 Diagnosis:
 H & P
 Clean catch midstream urine for U/A
 Cath urine if woman has vag. d/c, menstrual or vag.
Bleeding (cath urine will rarely exceed 3
RBC’s/hpf)
 Can screen with dipstick but false negs/pos may
result
 Abnormal RBC morphologic characteristics, RBC
casts & proteinuria suggest glomerular source
 If normal RBC’s then infection probable
 Imaging (IVP, CT, renal US)
 When haematuria(micro / Macro ) is noted
Nephrologist’s consultation should be
shout.
 Clinical Assessment
 Check the catheter, clinical examination of
renal tract , genital tract any other bleeding
sites
 Investigations:
 Complete urine examination, CBC, platelet
count , bleeding – clotting factor
profile, liver enzyme study should be
immediately ordered.
MANAGEMENT
 It depends upon the causes of hematuria

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Asymptomatic bacteriuria

  • 2. Defination  When a bacterial count of same species over 10^5 per ml in mild stream clean catch specimen of urine on two occasion is detected without the symptom of urinary infection it is called asymptomatic bacteriuria
  • 3.  Causes  Asymptomatic bacteriuria occurs in a small number of healthy individuals. It more often affects women than men. The reasons for the lack of symptoms are not well understood.  Most patients with asymptomatic bacteriuria do not need treatment because the bacteria are not causing any harm. Persons who have urinary catheters often will have bacteriuria, but most will not have symptoms.
  • 4.  The following increases your risk:  Diabetes  Infected kidney stones  Kidney transplant  Older age  Pregnancy -- up to 40% of pregnant women with untreated asymptomatic bacteriuria will develop a kidney infection  Vesicoureteral reflux in young children
  • 5. Symptoms  By definition, asymptomatic bacteriuria causes no symptoms. The symptoms of a urinary tract infection include burning during urination, an increased urgency to urinate, and increased frequency of urination.
  • 6. Exams and Tests  Asymptomatic bacteriuria is detected by the discovery of significant bacterial growth in a urine culture taken from a urine sample.
  • 7. Treatment  Pregnant women, kidney transplant recipients, children with vesicoureteral reflux, and those with infected kidney stones are more likely to be given antibiotics.  Giving antibiotics to persons who have long- term urinary catheters in place may cause additional problems. The bacteria may be more difficult to treat and the patients may develop a yeast infection.
  • 8.  If asymptomatic bacteriuria is found before a urinary tract procedure, it should be treated to prevent complications. The course of treatment in these cases depends on the person's risk factors.
  • 9. Possible Complications  Untreated, asymptomatic bacteriuria can lead to a kidney infection in high-risk individuals
  • 10. When to Contact a Medical Professional  Call your health care provider if the following symptoms occur:  Difficulty emptying your bladder  Fever  Flank or back pain  Pain with urination
  • 11. PROTEINURIA INPREGNANCY  When 2+protein in deepstick test it is called proteinuria  CAUSES  Pre-eclampsia and eclampsia  Urinary tract infection  Chronic Renal disease :Nephritis and Nephrotic Syndrome
  • 12.  Essential hypertension  Orthostatic- Due to increased lumbar lordosis there is increased pressure on the inferior Venacava by the uterus or left renal vein
  • 13.  Is compressed by the aorta this leads to congestion of one or both kidney leading to proteinuria.  In late pregnancy,the enlarged gravid utrerus may compress es the left renal vein when the patient is lying on supine position .lying down on lateral position relieves the pressure and congestion and makes the urine free of protein
  • 14.  Investigations (microscopic examination of Pus cells RBCs Cast cells)  Management depends upon etiology
  • 15. Hematuria in Pregnancy  Painful - infection  Painless – neoplastic, hyperplastic, vascular  Gross – urine appears ―RED‖; lower tract prob.  Microscopic – > 5 RBC’s/hpf; kidney dz  False hematuria = urine appears bloody, but dipstick results are neg. for blood and no RBC’s on micro Free hgb, myoglobin, porphyrins
  • 16. 1.Physological—menstruation 2. Infection—Pyelonephriitis , cystitis , urethritis , Tuberculosis of kidney and bladder 3. Trauma– Renal injury, Foreign body in bladder and urethra including catheter. 4.Inflammatory / autoimmune— Glomerulonephritis , Polyarteritis nodosa , Ch. Interstitial nephritis, radiatinal inflammation of renal tract.
  • 17. 5.Accidental haemorrhage 6.Rupture uterus 7. Obstructed labour 8 .DIC 9. Traumatic PPH
  • 18. 10.Heparine therapy for DVT 11.Eclampsia 12. HellP syndrome 13. Mismatched blood transfusion 14.Pregnancy associated with hematological diseases 15.Drug induced 16. Instrumental delivery 17.Traumatic VVF
  • 19. 5.Stones– renal , ureteric , bladder and urethra. 6 .Tumors– benign /malignant of renal tract. 7.General—drugs including anticoagulants Bleeding disorders , caruncle and prolapse of urethral mucosa.
  • 20.  Diagnosis:  H & P  Clean catch midstream urine for U/A  Cath urine if woman has vag. d/c, menstrual or vag. Bleeding (cath urine will rarely exceed 3 RBC’s/hpf)  Can screen with dipstick but false negs/pos may result  Abnormal RBC morphologic characteristics, RBC casts & proteinuria suggest glomerular source  If normal RBC’s then infection probable  Imaging (IVP, CT, renal US)
  • 21.  When haematuria(micro / Macro ) is noted Nephrologist’s consultation should be shout.  Clinical Assessment  Check the catheter, clinical examination of renal tract , genital tract any other bleeding sites
  • 22.  Investigations:  Complete urine examination, CBC, platelet count , bleeding – clotting factor profile, liver enzyme study should be immediately ordered.
  • 23. MANAGEMENT  It depends upon the causes of hematuria