2. INTRODUCTION
Birth asphyxia is the leading of neonatal mortility and
morbidity.
It is also an important causes of development delay
and neurological problems both in term and preterm
infants.
3. DEFINITION
Birth asphyxia is the non establishment of satisfactory
pulmonary respiration at birth.
Also known as Asphyxia Neonatorum
4. Etiology
Antepartum causes
Inadequate oxygenation of maternal blood due to
hypoventilation during anesthesia, heart diseases,
pneumonia, respiratory failure
Low maternal blood pressure due to hypotension e.g.
compression of vena cava and aorta, excess anaesthesia.
Premature separation of placenta
Placental insufficiency
Intra partum causes
Inadequate relaxation of uterus due to excess oxytocin
prolonged delivery
Knotting of umbilical cord around the neck of infant
5. Risk factors
Elderly or young mothers
Prolonged rupture of membranes
Meconium-stained fluid
Multiple births
Lack of antenatal care
Low birth weight infants
Malpresentation
Augmentation of labour with oxytocin
Antepartum hemorrhage
Severe eclampsia and pre-eclampsia
Antepartum and intrapartum anemia[10]
6. Clinical manifestations
Depends upon etiology, intensity, duration of oxygen
lack
Loss of muscle tone
Periodic & irregular breathing
Loss of reflexes
Apnea
Seizures
7. Diagnostic evaluation
Based on APGAR score
APGAR scoring system to be assessed immediately
after birth and after 5 minutes of birth:
1. 0-3- severe depression
2. 4-6- moderate depression
3. 7-10- no depression
8. Treatment
T= Maintenance of temperature
A= Establish open airway: Suctioning, if necessary
endotracheal intubation
B= Breathing: Through tactile stimulation, PPV, bag and
mask, or through endotracheal tube
C= Circulation: Through chest compressions and
medications if needed
D= Drugs: Adrenaline .01 of .1 solution
Hypothermia treatment to reduce the extent of brain injury
Epinephrine 1:10000 (0.1-0.3ml/kg) IV
Saline solution for hypovolemia