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The truth about

     painkillers
                     Dillies
                      Percs
                         ce
               Hillb Jui
                    illy
                         Heroi
                              n

      drugfreeworld.org
WHY THIS BOOKLET
    WAS PRODUCED
    T  here is a lot of talk about drugs in the world—on the streets,
       at school, on the Internet and TV. Some of it is true, some not.
    Much of what you hear about drugs actually comes from those selling
    them. Reformed drug dealers have confessed they would have said
    anything to get others to buy drugs.
    Don’t be fooled. You need facts to avoid becoming hooked on drugs
    and to help your friends stay off them. That is why we have prepared
    this booklet—for you.
    Your feedback is important to us, so we look forward to hearing from
    you. You can visit us on the web at drugfreeworld.org and e‑mail us
    at info@drugfreeworld.org.




2
Prescription Painkiller Abuse
W
            hile the use of many street drugs is       What is not known by
            on a slight decline in the US, abuse of    most of these young
            prescription drugs is growing. In 2007,    people is the risk they
2.5 million Americans abused prescription drugs        are taking by consuming
for the first time, compared to 2.1 million who used   these highly potent
marijuana for the first time.                          and mind‑altering
                                                       drugs. Long‑term use
Among teens, prescription drugs are the most
                                                       of painkillers can lead
commonly used drugs next to marijuana, and
                                                       to dependence, even
almost half of the teens abusing prescription drugs
                                                       for people who are prescribed them to relieve a
are taking painkillers.
                                                       medical condition but eventually fall into the trap
Why are so many young people turning to                of abuse and addiction.
prescription drugs to get high?
                                                       In some cases, the dangers of painkillers don’t
By survey, almost 50% of teens believe that taking     surface until it is too late. In 2007, for example,
prescription drugs is much safer than using illegal    abuse of the painkiller Fentanyl killed more than
street drugs.                                          1,000 people. The drug was found to be 30 to 50
                                                       times more powerful than heroin.
                                                                                                             3
What are Painkillers?
                      rescription painkillers are powerful drugs

               P      that interfere with the nervous system’s
                      transmission of the nerve signals we
               perceive as pain. Most painkillers also stimulate
               portions of the brain associated with pleasure.
               Thus, in addition to blocking pain, they produce
               a “high.”
               The most powerful prescription painkillers are
               called opioids, which are opium‑like* compounds.
               They are manufactured to react on the nervous
               system in the same way as drugs derived from the
               opium poppy, like heroin. The most commonly
               abused opioid painkillers include oxycodone,
               hydrocodone, meperidine, hydromorphone and
                 propoxyphene.

                    *	 opium: a brownish, gummy extract from the opium poppy.




4
Oxycodone has the greatest potential for           this drug have increased significantly in recent
abuse and the greatest dangers. It is as           years, as has its illicit use.
powerful as heroin and affects the nervous
                                                   Meperidine (brand name Demerol) and
system the same way. Oxycodone is sold
                                                   hydromorphone (Dilaudid) come in tablets
under many trade names, such as Percodan,
                                                   and propoxyphene (Darvon) in capsules, but
Endodan, Roxiprin, Percocet, Endocet, Roxicet
                                                   all three have been known to be crushed and
and OxyContin. It comes in tablet form.
                                                   injected, snorted or smoked. Darvon, banned
Hydrocodone is used in combination with            in the UK since 2005, is among the top ten
other chemicals and is available in prescription   drugs reported in drug abuse deaths in the US.
pain medications as tablets, capsules and          Dilaudid, considered eight times more potent
syrups. Trade names include Anexsia, Dicodid,      than morphine, is often called “drug store
Hycodan, Hycomine, Lorcet, Lortab, Norco,          heroin” on the streets.
Tussionex and Vicodin. Sales and production of




                                                                                                      5
“At the age of 20, I became an addict to a narcotic*
           which began with a prescription following a surgery. In the weeks
        that followed [the operation] in addition to orally abusing the tablet,
      crushing it up enabled me to destroy the controlled release mechanism
           and to swallow or snort the drug. It can also be injected to
       produce a feeling identical to shooting heroin. The physical
               withdrawal from the drug is nothing short of agonizing pain.”
    	                                                                 — James




     *	 narcotic: a drug affecting the central nervous system (brain and spinal cord), which can cause dizziness, lack of coordination
        and unconsciousness.
6
Street Names for Painkillers
Generic Name    Brand Name               Street Name
Oxycodone       OxyContin, Percodan,     Oxy 80s, oxycotton,
                Percocet, Roxiprin,      oxycet, hillbilly heroin,
                Roxicet, Endodan,        percs, perks
                Endocet

Hydrocodone     Anexsia, Dicodid,        pain killer, vikes,
                Hycodan, Hycomine,       hydros
                Lorcet, Lortab, Norco,
                Tussionex, Vicodin

Propoxyphene    Darvon                   pinks, footballs, pink
                                         footballs, yellow
                                         footballs, 65’s, Ns

Hydromorphone   Dilaudid                 juice, dillies, drug street
                                         heroin

Meperidine      Demerol                  demmies, pain killer
                                                                       7
Understanding Why Painkillers
    		 Become So addictive
    O
            pioid painkillers produce a short‑lived       a tolerance to the drug, meaning that higher
            euphoria, but they are also addictive.        doses have to be taken to achieve the same
                                                          effects.
             Long‑term use of painkillers can lead
    to physical dependence. The body adapts               Like all drugs, painkillers simply mask the pain
    to the presence of the substance and if one           for which they are taken. They don’t “cure”
    stops taking the drug abruptly, withdrawal            anything. Someone continuously trying to dull
    symptoms occur. Or the body could build up            the pain may find himself taking higher and


                                 “I am addicted to prescription pain medication.
                   I first started taking prescription painkillers [some] years ago when
                my doctor prescribed them to treat post‑surgical pain following spinal
                 surgery. . . . Over the past several years I have tried to break my
                  dependence on pain pills and, in fact, twice checked myself into
                medical facilities in an attempt to do so. [I have] recently agreed with
                                                      my physician about the next steps.”
                                        — Excerpted from radio commentator Rush Limbaugh’s on‑air statement,
8                                            Friday, Oct. 10, 2003, according to Premiere Radio, his broadcaster.
Family members protest deadly
                          painkillers. Rehab experts say addiction
                          to powerful painkillers such as OxyContin
                          is among the hardest of all to kick.



higher doses—only to discover that he cannot
make it through the day without the drug.
Symptoms of withdrawal can include
restlessness, muscle and bone pain, insomnia,
diarrhea, vomiting, cold flashes with goose
bumps (known as “cold turkey”), and
involuntary leg movements.
One of the serious risks of opioids is
respiratory depression—high doses can cause
breathing to slow down to the point it stops
and the user dies.




                                                                      9
OxyContin
     		             The “Hillbilly Heroin”

     B
            ecause it reacts on the nervous        communities, has emerged as a major crime
            system like heroin or opium, some      problem in the US. In one county, it was
            abusers are using one brand of         estimated that addiction to this drug was
     oxycodone painkiller, OxyContin, as a         behind 80% of the crime.
     substitute for, or supplement to, street
     opiates like heroin.
     Armed robberies of pharmacies have
     occurred where the robber demanded
     only OxyContin, not cash. In some areas,
     particularly the Eastern United States,
     OxyContin has been the drug of greatest
     concern to law enforcement authorities.
     OxyContin, widely known as “hillbilly
     heroin” because of its abuse in Appalachian



10
“I didn’t think I had a ‘drug’
problem—I was buying
the tablets at the chemist
[drugstore]. It didn’t affect my
work. I would feel a bit tired in
the mornings, but nothing more.
The fact that I had a problem
came to a head when I took an
overdose of about 40 tablets
and found myself in the
hospital. I spent 12 weeks
in the clinic conquering my
addiction.”
		                — Alex

                                    11
“Pretty much as long as I can remember
     I’ve had highs and lows. I would get
     easily upset by the littlest things,
     I would have anger outbursts,
     or hate someone for no reason at all. For
     a long while I had thought I was bipolar.
     I started using drugs last October to help
     me with my unwanted feelings. But
     believe it or not, it just made stuff
             !
     worse I had to now deal with my addiction
     and my emotional problems.”
     		               — Thomas


12
Mental & Physiological
	Effects of Painkillers
 • constipation
 • nausea
 • vomiting
 • dizziness
 • confusion
 • addiction
 • unconsciousness
 • respiratory depression
 • increased risk of heart attack
 • coma
 • death


                                    13
Painkillers:
     		A Short History
     O
              piates, originally derived from
              the opium poppy, have been used            Highly addictive
              for thousands of years for both            opiates, derived
     recreational and medicinal purposes. The most       from the opium
                                                         poppy, have
     active substance in opium is morphine—named
                                                         been used for
     after Morpheus, the Greek god of dreams.            thousands of
     Morphine is a very powerful painkiller, but it is   years for both
     also very addictive.                                recreational
                                                         and medicinal
     In the 16th century, laudanum, opium prepared       purposes.
     in an alcoholic solution, was used as a
     painkiller.
     Morphine was first extracted from opium in a
     pure form in the early 19th century. It was used
     widely as a painkiller during the American Civil
     War, and many soldiers became addicted.



14
Morphine, the most
    active substance
   in opium, is a very
  powerful painkiller
  that hooked many
US Civil War soldiers.




               15
A bottle         Codeine, a less powerful drug that is found in
      of codeine      opium but can be synthesized (man‑made), was
      tablets—all
       opiates
                      first isolated in 1830 in France by Jean‑Pierre
       temporarily    Robiquet, to replace raw opium for medical
      relieve pain    purposes. It is used mainly as a cough remedy.
     but are highly
       addictive.     Throughout the early 19th century, the
                      recreational use of opium grew and by 1830,
                      the British dependence on the drug reached
                      an all‑time high. The British sent warships
                      to the coast of China in 1839 in response to
                      China’s attempt to suppress the opium traffic,
                      beginning the “First Opium War.”
                      In 1874, chemists trying to find a less addictive
                      form of morphine made heroin. But heroin had
                      twice the potency of morphine, and heroin
                      addiction soon became a serious problem.
                      The US Congress banned opium in 1905 and the
                      next year passed the Pure Food and Drug Act
                      requiring contents labeling on all medicines.
                      Methadone was first synthesized in 1937
                       by German scientists Max Bockmühl and

16
Gustav Ehrhart at the IG Farben company.
They were searching for a painkiller that
would be easier to use during surgery, with less
addiction potential than morphine or heroin.
Yet methadone is believed by many to be even
more addictive than heroin.
Meanwhile, the illegal opium trade boomed.
By 1995, Southeast Asia was producing
2,500 tons annually.
New painkillers came on the market
with approval from the Food and Drug
Administration: Vicodin in 1984, OxyContin
in 1995 and Percocet in 1999. These
are all synthetic (man‑made) opiates
which mimic (imitate) the body’s own
painkillers.

   The stamp of IG Farben, the
      German company whose
chemists Bockmühl and Ehrhart
     developed the formula for
methadone (right)—a synthetic
                 form of heroin.
International
     		Statistics
     A
             mong those using illicit drugs for the     was found as the cause of 785 deaths in
             first time in 2007, the most popular       one state alone, Florida, in 2007.
             substances were marijuana and
                                                        Prescription drug abuse is also climbing
     prescription painkillers—each used by roughly
                                                        in older Americans, particularly
     the same number of Americans aged 12 and
                                                        involving anti‑anxiety drugs such
     older. Non‑medical use of painkillers rose 12%.
                                                        as Xanax and painkillers such as
     One in 10 high school seniors in the US admits     OxyContin.
     to abusing prescription painkillers.
                                                        In the UK, tens of thousands of people
     Misuse of painkillers represents three‑fourths     are said to be dependent on painkillers
     of the overall problem of prescription drug        such as Solpadeine and Neurofen Plus.
     abuse. The painkiller hydrocodone is the most
                                                        Doctors and rehabilitation therapists
     commonly diverted and abused controlled
                                                        report that prescription painkiller abuse
     pharmaceutical in the US.
                                                        is one of the most difficult addictions
     Methadone, once used in addiction treatment        to treat.
     centers and now used by doctors as a painkiller,

18
Warning Signs
of Prescription Painkiller Dependency
      ost commonly prescribed painkillers                5. 	 Time spent on obtaining prescriptions: spending
M     (OxyContin, Vicodin, Methadone, Darvocet,
Lortab, Lorcet and Percocet), while offering relief
                                                              large amounts of time driving great distances
                                                              and visiting multiple doctors to obtain the drugs.
from pain, can also cause individuals’ bodies to start   6. 	 Change in daily habits and appearance: decline
“needing” the drugs in order to feel just “normal.”           in personal hygiene; change in sleeping and
Here are ten warning signs to watch for if you                eating habits; constant cough, running nose
think someone you know may be experiencing a                  and red, glazed eyes.
dependency on these drugs:                               7. 	 Neglects responsibilities: neglect of household
                                                              chores and bills; calling in sick to school or work
1. 	Usage increase: increase of one’s dose over
                                                              more often.
    time, as a result of growing tolerant to the drug
    and needing more to get the same effect.             8. 	 Increased sensitivity: normal sights, sounds and
                                                              emotions becoming overly stimulating to the
2. 	 Change in personality: shifts in energy, mood,
                                                              person; hallucinations.
     and concentration as a result of everyday
     responsibilities becoming secondary to the          9. 	Blackouts and forgetfulness: forgetting events
     need for the drug.                                      that have taken place and experiencing
                                                             blackouts.
3. 	 Social withdrawal: withdrawal from family and
     friends.                                            10.	 Defensiveness: becoming defensive and
                                                              lashing out in response to simple questions in
4. 	Ongoing use: continued use of painkillers after
                                                              an attempt to hide a drug dependency, if users
    the medical condition they were meant to
                                                              feel their secret is being discovered.
    relieve has improved.

                                                                                                           19
The Truth
  	 About Drugs
D   rugs are essentially poisons. The amount
    taken determines the effect.
                                                        Drugs block off all sensations, the desirable ones
                                                        with the unwanted. So, while providing short‑term
                                                        help in the relief of pain, they also wipe out ability
A small amount acts as a stimulant (speeds you
                                                        and alertness and muddy one’s thinking.
up). A greater amount acts as a sedative (slows
you down). An even larger amount poisons and            Medicines are drugs that are intended to speed up
can kill.                                               or slow down or change something about the way
                                                        your body is working, to try to make it work better.
This is true of any drug. Only the amount needed
                                                        Sometimes they are necessary. But they are still
to achieve the effect differs.
                                                        drugs: they act as stimulants or sedatives, and too
But many drugs have another liability: they             much can kill you. So if you do not use medicines
directly affect the mind. They can distort the user’s   as they are supposed to be used, they can be as
perception of what is happening around him or           dangerous as illegal drugs.
her. As a result, the person’s actions may be odd,
irrational, inappropriate and even destructive.

20
The real answer is to get
the facts and not to take
drugs in the first place.




                            21
why do people take drugs?
 People take drugs because they want to   They think drugs are a solution. But
 change something in their lives.         eventually, the drugs become the
                                          problem.
 Here are some of the reasons young
 people have given for taking drugs:      Difficult as it may be to face one’s
                                          problems, the consequences of drug use
 • To fit in
                                          are always worse than the problem one
 • To escape or relax                     is trying to solve with them. The real
                                          answer is to get the facts and not to take
 • To relieve boredom
                                          drugs in the first place.
 • To seem grown up
 • To rebel
 • To experiment




22
Millions of copies of booklets such as
REFERENCES:                           OxyContin: Prescription Drug Abuse
                                                                              this have been distributed to people
                                      Advisory, Center for ­Substance
Drug Enforcement Administration
Fact Sheet on Prescription Drug
                                      Abuse Treatment (CSAT)                  around the world in 22 languages. As
Abuse                                 National Institute on Drug Abuse        new drugs appear on the streets and more
                                      (NIDA), Info Facts: Prescription Pain
“Older Americans fight drug abuse,”
                                      and Other Medications                   information about their effects becomes
3 Jul 2008, International Herald
Tribune                               National Institute on Drug Abuse        known, existing booklets are updated and
                                      Research Report, “Prescription
“Methadone rises as a painkiller
                                      Drugs, Abuse and Addiction 2001”
                                                                              new ones created.
with big risks,” 17 Aug 2008,
                                      “Some Commonly Prescribed
International Herald Tribune
                                      Medications: Use and
                                                                              The booklets are published by the
“Nurofen Plus to remain on sale,”
6 Aug 2008
                                      Consequences,” National Institute       Foundation for a Drug‑Free World, a
                                      on Drug Abuse
“Warning on painkillers,” 5 April                                             nonprofit public benefit organization
                                      National Institute of Justice, Drug
2007, Financial Times
                                      and Alcohol Use and Related             headquartered in Los Angeles, California.
2007 National Survey on Drug          M
                                      ­ atters Among Arrestees, 2003
Use and Health, U.S. Substance
                                      U.S. Office of National Drug Control    The Foundation provides educational
Abuse and Mental Health Services
Administration
                                      Policy, “Drug Facts: OxyContin,” and    materials, advice and coordination for its
                                      “Prescription Drug Facts & Figures”
“Depressants,” U.S. Department
                                      “New Report Reveals More Than
                                                                              international drug prevention network.
of Health & Human Services and
SAMHSA’s National Clearinghouse
                                      1000 People Died in Illegal Fentanyl    It works with youth, parents, educators,
                                      Epidemic of 2005‑2007,” Substance
for Alcohol & Drug Information
                                      Abuse and Mental Health Services
                                                                              volunteer organizations and government
ABC of drugs, channel4.com            Administration                          agencies—anyone with an interest in
A Brief History of Opium,             “Teen OTC & Prescription                helping people lead lives free from drug
opioids.com                           Drug Abuse,”
OxyContin Information, National
                                      teenoverthecounterdrugabuse.com         abuse.
Clearinghouse on Alcohol and Drug     PHOTO CREDITS: Page 9:
Information                           OxyABUSEkills.com/protest; Page
                                      14 & 15: AP Wideworld.                                                      23
FACTS YOU NEED TO KNOW
This booklet is one in a series of publications that cover the facts about marijuana, alcohol,
Ecstasy, cocaine, crack cocaine, crystal meth and methamphetamine, inhalants, heroin,
LSD and prescription drug abuse. Armed with this information, the reader can make the
decision to live a drug‑free life.


                                    For more information or to obtain more copies
                                    of this or other booklets in this series, contact:
                                                    Foundation for a Drug‑Free World
                                                     1626 N. Wilcox Avenue, #1297
                                                      Los Angeles, CA 90028 USA
                                           drugfreeworld.org • e‑mail: info@drugfreeworld.org
                        TM                   Phone: 1‑888 NO TO DRUGS (1‑888‑668‑6378)


© 2008 Foundation for a Drug‑Free World. All Rights Reserved. The Foundation logo is a trademark owned by the
Foundation for a Drug‑Free World. Item #C6231 US-ENG

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Truth about-painkillers-booklet-en

  • 1. The truth about painkillers Dillies Percs ce Hillb Jui illy Heroi n drugfreeworld.org
  • 2. WHY THIS BOOKLET WAS PRODUCED T here is a lot of talk about drugs in the world—on the streets, at school, on the Internet and TV. Some of it is true, some not. Much of what you hear about drugs actually comes from those selling them. Reformed drug dealers have confessed they would have said anything to get others to buy drugs. Don’t be fooled. You need facts to avoid becoming hooked on drugs and to help your friends stay off them. That is why we have prepared this booklet—for you. Your feedback is important to us, so we look forward to hearing from you. You can visit us on the web at drugfreeworld.org and e‑mail us at info@drugfreeworld.org. 2
  • 3. Prescription Painkiller Abuse W hile the use of many street drugs is What is not known by on a slight decline in the US, abuse of most of these young prescription drugs is growing. In 2007, people is the risk they 2.5 million Americans abused prescription drugs are taking by consuming for the first time, compared to 2.1 million who used these highly potent marijuana for the first time. and mind‑altering drugs. Long‑term use Among teens, prescription drugs are the most of painkillers can lead commonly used drugs next to marijuana, and to dependence, even almost half of the teens abusing prescription drugs for people who are prescribed them to relieve a are taking painkillers. medical condition but eventually fall into the trap Why are so many young people turning to of abuse and addiction. prescription drugs to get high? In some cases, the dangers of painkillers don’t By survey, almost 50% of teens believe that taking surface until it is too late. In 2007, for example, prescription drugs is much safer than using illegal abuse of the painkiller Fentanyl killed more than street drugs. 1,000 people. The drug was found to be 30 to 50 times more powerful than heroin. 3
  • 4. What are Painkillers? rescription painkillers are powerful drugs P that interfere with the nervous system’s transmission of the nerve signals we perceive as pain. Most painkillers also stimulate portions of the brain associated with pleasure. Thus, in addition to blocking pain, they produce a “high.” The most powerful prescription painkillers are called opioids, which are opium‑like* compounds. They are manufactured to react on the nervous system in the same way as drugs derived from the opium poppy, like heroin. The most commonly abused opioid painkillers include oxycodone, hydrocodone, meperidine, hydromorphone and propoxyphene. * opium: a brownish, gummy extract from the opium poppy. 4
  • 5. Oxycodone has the greatest potential for this drug have increased significantly in recent abuse and the greatest dangers. It is as years, as has its illicit use. powerful as heroin and affects the nervous Meperidine (brand name Demerol) and system the same way. Oxycodone is sold hydromorphone (Dilaudid) come in tablets under many trade names, such as Percodan, and propoxyphene (Darvon) in capsules, but Endodan, Roxiprin, Percocet, Endocet, Roxicet all three have been known to be crushed and and OxyContin. It comes in tablet form. injected, snorted or smoked. Darvon, banned Hydrocodone is used in combination with in the UK since 2005, is among the top ten other chemicals and is available in prescription drugs reported in drug abuse deaths in the US. pain medications as tablets, capsules and Dilaudid, considered eight times more potent syrups. Trade names include Anexsia, Dicodid, than morphine, is often called “drug store Hycodan, Hycomine, Lorcet, Lortab, Norco, heroin” on the streets. Tussionex and Vicodin. Sales and production of 5
  • 6. “At the age of 20, I became an addict to a narcotic* which began with a prescription following a surgery. In the weeks that followed [the operation] in addition to orally abusing the tablet, crushing it up enabled me to destroy the controlled release mechanism and to swallow or snort the drug. It can also be injected to produce a feeling identical to shooting heroin. The physical withdrawal from the drug is nothing short of agonizing pain.” — James * narcotic: a drug affecting the central nervous system (brain and spinal cord), which can cause dizziness, lack of coordination and unconsciousness. 6
  • 7. Street Names for Painkillers Generic Name Brand Name Street Name Oxycodone OxyContin, Percodan, Oxy 80s, oxycotton, Percocet, Roxiprin, oxycet, hillbilly heroin, Roxicet, Endodan, percs, perks Endocet Hydrocodone Anexsia, Dicodid, pain killer, vikes, Hycodan, Hycomine, hydros Lorcet, Lortab, Norco, Tussionex, Vicodin Propoxyphene Darvon pinks, footballs, pink footballs, yellow footballs, 65’s, Ns Hydromorphone Dilaudid juice, dillies, drug street heroin Meperidine Demerol demmies, pain killer 7
  • 8. Understanding Why Painkillers Become So addictive O pioid painkillers produce a short‑lived a tolerance to the drug, meaning that higher euphoria, but they are also addictive. doses have to be taken to achieve the same effects. Long‑term use of painkillers can lead to physical dependence. The body adapts Like all drugs, painkillers simply mask the pain to the presence of the substance and if one for which they are taken. They don’t “cure” stops taking the drug abruptly, withdrawal anything. Someone continuously trying to dull symptoms occur. Or the body could build up the pain may find himself taking higher and “I am addicted to prescription pain medication. I first started taking prescription painkillers [some] years ago when my doctor prescribed them to treat post‑surgical pain following spinal surgery. . . . Over the past several years I have tried to break my dependence on pain pills and, in fact, twice checked myself into medical facilities in an attempt to do so. [I have] recently agreed with my physician about the next steps.” — Excerpted from radio commentator Rush Limbaugh’s on‑air statement, 8 Friday, Oct. 10, 2003, according to Premiere Radio, his broadcaster.
  • 9. Family members protest deadly painkillers. Rehab experts say addiction to powerful painkillers such as OxyContin is among the hardest of all to kick. higher doses—only to discover that he cannot make it through the day without the drug. Symptoms of withdrawal can include restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps (known as “cold turkey”), and involuntary leg movements. One of the serious risks of opioids is respiratory depression—high doses can cause breathing to slow down to the point it stops and the user dies. 9
  • 10. OxyContin The “Hillbilly Heroin” B ecause it reacts on the nervous communities, has emerged as a major crime system like heroin or opium, some problem in the US. In one county, it was abusers are using one brand of estimated that addiction to this drug was oxycodone painkiller, OxyContin, as a behind 80% of the crime. substitute for, or supplement to, street opiates like heroin. Armed robberies of pharmacies have occurred where the robber demanded only OxyContin, not cash. In some areas, particularly the Eastern United States, OxyContin has been the drug of greatest concern to law enforcement authorities. OxyContin, widely known as “hillbilly heroin” because of its abuse in Appalachian 10
  • 11. “I didn’t think I had a ‘drug’ problem—I was buying the tablets at the chemist [drugstore]. It didn’t affect my work. I would feel a bit tired in the mornings, but nothing more. The fact that I had a problem came to a head when I took an overdose of about 40 tablets and found myself in the hospital. I spent 12 weeks in the clinic conquering my addiction.” — Alex 11
  • 12. “Pretty much as long as I can remember I’ve had highs and lows. I would get easily upset by the littlest things, I would have anger outbursts, or hate someone for no reason at all. For a long while I had thought I was bipolar. I started using drugs last October to help me with my unwanted feelings. But believe it or not, it just made stuff ! worse I had to now deal with my addiction and my emotional problems.” — Thomas 12
  • 13. Mental & Physiological Effects of Painkillers • constipation • nausea • vomiting • dizziness • confusion • addiction • unconsciousness • respiratory depression • increased risk of heart attack • coma • death 13
  • 14. Painkillers: A Short History O piates, originally derived from the opium poppy, have been used Highly addictive for thousands of years for both opiates, derived recreational and medicinal purposes. The most from the opium poppy, have active substance in opium is morphine—named been used for after Morpheus, the Greek god of dreams. thousands of Morphine is a very powerful painkiller, but it is years for both also very addictive. recreational and medicinal In the 16th century, laudanum, opium prepared purposes. in an alcoholic solution, was used as a painkiller. Morphine was first extracted from opium in a pure form in the early 19th century. It was used widely as a painkiller during the American Civil War, and many soldiers became addicted. 14
  • 15. Morphine, the most active substance in opium, is a very powerful painkiller that hooked many US Civil War soldiers. 15
  • 16. A bottle Codeine, a less powerful drug that is found in of codeine opium but can be synthesized (man‑made), was tablets—all opiates first isolated in 1830 in France by Jean‑Pierre temporarily Robiquet, to replace raw opium for medical relieve pain purposes. It is used mainly as a cough remedy. but are highly addictive. Throughout the early 19th century, the recreational use of opium grew and by 1830, the British dependence on the drug reached an all‑time high. The British sent warships to the coast of China in 1839 in response to China’s attempt to suppress the opium traffic, beginning the “First Opium War.” In 1874, chemists trying to find a less addictive form of morphine made heroin. But heroin had twice the potency of morphine, and heroin addiction soon became a serious problem. The US Congress banned opium in 1905 and the next year passed the Pure Food and Drug Act requiring contents labeling on all medicines. Methadone was first synthesized in 1937 by German scientists Max Bockmühl and 16
  • 17. Gustav Ehrhart at the IG Farben company. They were searching for a painkiller that would be easier to use during surgery, with less addiction potential than morphine or heroin. Yet methadone is believed by many to be even more addictive than heroin. Meanwhile, the illegal opium trade boomed. By 1995, Southeast Asia was producing 2,500 tons annually. New painkillers came on the market with approval from the Food and Drug Administration: Vicodin in 1984, OxyContin in 1995 and Percocet in 1999. These are all synthetic (man‑made) opiates which mimic (imitate) the body’s own painkillers. The stamp of IG Farben, the German company whose chemists Bockmühl and Ehrhart developed the formula for methadone (right)—a synthetic form of heroin.
  • 18. International Statistics A mong those using illicit drugs for the was found as the cause of 785 deaths in first time in 2007, the most popular one state alone, Florida, in 2007. substances were marijuana and Prescription drug abuse is also climbing prescription painkillers—each used by roughly in older Americans, particularly the same number of Americans aged 12 and involving anti‑anxiety drugs such older. Non‑medical use of painkillers rose 12%. as Xanax and painkillers such as One in 10 high school seniors in the US admits OxyContin. to abusing prescription painkillers. In the UK, tens of thousands of people Misuse of painkillers represents three‑fourths are said to be dependent on painkillers of the overall problem of prescription drug such as Solpadeine and Neurofen Plus. abuse. The painkiller hydrocodone is the most Doctors and rehabilitation therapists commonly diverted and abused controlled report that prescription painkiller abuse pharmaceutical in the US. is one of the most difficult addictions Methadone, once used in addiction treatment to treat. centers and now used by doctors as a painkiller, 18
  • 19. Warning Signs of Prescription Painkiller Dependency ost commonly prescribed painkillers 5. Time spent on obtaining prescriptions: spending M (OxyContin, Vicodin, Methadone, Darvocet, Lortab, Lorcet and Percocet), while offering relief large amounts of time driving great distances and visiting multiple doctors to obtain the drugs. from pain, can also cause individuals’ bodies to start 6. Change in daily habits and appearance: decline “needing” the drugs in order to feel just “normal.” in personal hygiene; change in sleeping and Here are ten warning signs to watch for if you eating habits; constant cough, running nose think someone you know may be experiencing a and red, glazed eyes. dependency on these drugs: 7. Neglects responsibilities: neglect of household chores and bills; calling in sick to school or work 1. Usage increase: increase of one’s dose over more often. time, as a result of growing tolerant to the drug and needing more to get the same effect. 8. Increased sensitivity: normal sights, sounds and emotions becoming overly stimulating to the 2. Change in personality: shifts in energy, mood, person; hallucinations. and concentration as a result of everyday responsibilities becoming secondary to the 9. Blackouts and forgetfulness: forgetting events need for the drug. that have taken place and experiencing blackouts. 3. Social withdrawal: withdrawal from family and friends. 10. Defensiveness: becoming defensive and lashing out in response to simple questions in 4. Ongoing use: continued use of painkillers after an attempt to hide a drug dependency, if users the medical condition they were meant to feel their secret is being discovered. relieve has improved. 19
  • 20. The Truth About Drugs D rugs are essentially poisons. The amount taken determines the effect. Drugs block off all sensations, the desirable ones with the unwanted. So, while providing short‑term help in the relief of pain, they also wipe out ability A small amount acts as a stimulant (speeds you and alertness and muddy one’s thinking. up). A greater amount acts as a sedative (slows you down). An even larger amount poisons and Medicines are drugs that are intended to speed up can kill. or slow down or change something about the way your body is working, to try to make it work better. This is true of any drug. Only the amount needed Sometimes they are necessary. But they are still to achieve the effect differs. drugs: they act as stimulants or sedatives, and too But many drugs have another liability: they much can kill you. So if you do not use medicines directly affect the mind. They can distort the user’s as they are supposed to be used, they can be as perception of what is happening around him or dangerous as illegal drugs. her. As a result, the person’s actions may be odd, irrational, inappropriate and even destructive. 20
  • 21. The real answer is to get the facts and not to take drugs in the first place. 21
  • 22. why do people take drugs? People take drugs because they want to They think drugs are a solution. But change something in their lives. eventually, the drugs become the problem. Here are some of the reasons young people have given for taking drugs: Difficult as it may be to face one’s problems, the consequences of drug use • To fit in are always worse than the problem one • To escape or relax is trying to solve with them. The real answer is to get the facts and not to take • To relieve boredom drugs in the first place. • To seem grown up • To rebel • To experiment 22
  • 23. Millions of copies of booklets such as REFERENCES: OxyContin: Prescription Drug Abuse this have been distributed to people Advisory, Center for ­Substance Drug Enforcement Administration Fact Sheet on Prescription Drug Abuse Treatment (CSAT) around the world in 22 languages. As Abuse National Institute on Drug Abuse new drugs appear on the streets and more (NIDA), Info Facts: Prescription Pain “Older Americans fight drug abuse,” and Other Medications information about their effects becomes 3 Jul 2008, International Herald Tribune National Institute on Drug Abuse known, existing booklets are updated and Research Report, “Prescription “Methadone rises as a painkiller Drugs, Abuse and Addiction 2001” new ones created. with big risks,” 17 Aug 2008, “Some Commonly Prescribed International Herald Tribune Medications: Use and The booklets are published by the “Nurofen Plus to remain on sale,” 6 Aug 2008 Consequences,” National Institute Foundation for a Drug‑Free World, a on Drug Abuse “Warning on painkillers,” 5 April nonprofit public benefit organization National Institute of Justice, Drug 2007, Financial Times and Alcohol Use and Related headquartered in Los Angeles, California. 2007 National Survey on Drug M ­ atters Among Arrestees, 2003 Use and Health, U.S. Substance U.S. Office of National Drug Control The Foundation provides educational Abuse and Mental Health Services Administration Policy, “Drug Facts: OxyContin,” and materials, advice and coordination for its “Prescription Drug Facts & Figures” “Depressants,” U.S. Department “New Report Reveals More Than international drug prevention network. of Health & Human Services and SAMHSA’s National Clearinghouse 1000 People Died in Illegal Fentanyl It works with youth, parents, educators, Epidemic of 2005‑2007,” Substance for Alcohol & Drug Information Abuse and Mental Health Services volunteer organizations and government ABC of drugs, channel4.com Administration agencies—anyone with an interest in A Brief History of Opium, “Teen OTC & Prescription helping people lead lives free from drug opioids.com Drug Abuse,” OxyContin Information, National teenoverthecounterdrugabuse.com abuse. Clearinghouse on Alcohol and Drug PHOTO CREDITS: Page 9: Information OxyABUSEkills.com/protest; Page 14 & 15: AP Wideworld. 23
  • 24. FACTS YOU NEED TO KNOW This booklet is one in a series of publications that cover the facts about marijuana, alcohol, Ecstasy, cocaine, crack cocaine, crystal meth and methamphetamine, inhalants, heroin, LSD and prescription drug abuse. Armed with this information, the reader can make the decision to live a drug‑free life. For more information or to obtain more copies of this or other booklets in this series, contact: Foundation for a Drug‑Free World 1626 N. Wilcox Avenue, #1297 Los Angeles, CA 90028 USA drugfreeworld.org • e‑mail: info@drugfreeworld.org TM Phone: 1‑888 NO TO DRUGS (1‑888‑668‑6378) © 2008 Foundation for a Drug‑Free World. All Rights Reserved. The Foundation logo is a trademark owned by the Foundation for a Drug‑Free World. Item #C6231 US-ENG