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Introduction to the Semantic Web

From mza, 2 years ago Add as contact

A quick introduction to the Semantic Web, and how to start publishing semantic data in biology.

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  1. Slide 2: “ The Semantic Web is not a separate Web but an extension of the current one, in which information is given well-defined meaning, better enabling ” computers and people to work in cooperation Sir Tim, 2002
  2. Slide 3: “ AWESOME ” Me, just now
  3. Slide 4: “ The Semantic Web is not a separate Web but an extension of the current one, in which information is given well-defined meaning, better enabling ” computers and people to work in cooperation Sir Tim, 2002 not quite true
  4. Slide 5: Documents vs Data
  5. Slide 6: XML and URI Uniform resource identifiers and namespaces
  6. Slide 7: <rdf:RDF xmlns="http://www.affymetrix.com/community/ publications/affymetrix/tmsplice#"
  7. Slide 9: RDF and OWL Resource Description Format and the Web Ontology Language
  8. Slide 10: <Gene rdf:about="#1110002A21Rik"> <chr>chr1</chr> <hasVariant rdf:parseType="Resource"> <representedBy rdf:resource="#gi13385627"/> </hasVariant> <hasVariant rdf:parseType="Resource"> <representedBy rdf:resource="#gi18043402"/> </hasVariant> <strand>+</strand> </Gene>
  9. Slide 11: <Exon rdf:about="#1110002A21Rik_e3"> <commonToAll>1</commonToAll> <startsAt>37936751</startsAt> <stopsAt>37937035</stopsAt> </Exon>
  10. Slide 12: <Transcript rdf:about="#gi13385627"> <hasCds rdf:parseType="Resource"> <startsAt>37936755</startsAt> <stopsAt>37944277</stopsAt> </hasCds> <hasExon rdf:parseType="Resource"> <cdsType>None</cdsType> <relatesToExon rdf:resource="#1110002A21Rik_e3"/> </hasExon> ... </Transcript>
  11. Slide 13: RDF Schema Formal XML definition for an RDF file
  12. Slide 14: SPARQL Standard RDF query language
  13. Slide 15: WTF?
  14. Slide 16: too ambitious?
  15. Slide 17: let’s go with what works now
  16. Slide 18: lower case ‘s’, lower case ‘w’ The semantic web, not The Semantic Web
  17. Slide 19: Add semantic value to data in existing documents
  18. Slide 20: <tr> <th class="two-column">Gene</th> <td class="two-column"><table width="100%" cellpadding="4"> <tr> <td><strong> <a href="http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/ get_data.pl?hgnc_id=1101">BRCA2</a></div></strong> (HGNC Symbol) </td> <td> <span class="small"> To view all Ensembl genes linked to the name <a href="/Homo_sapiens/featureview? type=Gene;id=BRCA2">click here</a>.</span> </td> </tr> </table><p> This gene is a member of the Human CCDS set: <a href="http:// www.ncbi.nlm.nih.gov/CCDS/CcdsBrowse.cgi? REQUEST=CCDS&amp;DATA=CCDS9344">CCDS9344</a> </p> </td> </tr>
  19. Slide 21: <tr class="hgene"> <th class="two-column">Gene</th> <td class="two-column"><table width="100%" cellpadding="4"> <tr> <td><strong> <a href="http://www.gene.ucl.ac.uk/cgi-bin/nomenclature/ get_data.pl?hgnc_id=1101" rel="hgnc_name">BRCA2</a></div></ strong> (HGNC Symbol) </td> <td> <span class="small"> To view all Ensembl genes linked to the name <a href="/Homo_sapiens/featureview?type=Gene;id=BRCA2" rel="gene_list" >click here</a>.</span> </td> </tr> </table><p> This gene is a member of the Human CCDS set: <a href="http:// www.ncbi.nlm.nih.gov/CCDS/CcdsBrowse.cgi? REQUEST=CCDS&amp;DATA=CCDS9344" rel="ccds">CCDS9344</a> </p> </td> </tr>
  20. Slide 22: Cool, me too! I’m going to mark up genes like this Cool, me too! Cool, me too! Cool, me too! Cool, me to Apologies to Dan Cederholm: simplebits.com
  21. Slide 23: Style it. Parse it.
  22. Slide 24: Can our website be our API?
  23. Slide 25: http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000139618
  24. Slide 26: http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000139618 my $gene_adaptor = $registry->get_adaptor( 'Human', 'Core', 'Gene' ); my $gene = fetch_by_gene_stable_id( 'ENSG00000139618' );
  25. Slide 27: More data on the web than from the API (we’re not the only ones)
  26. Slide 29: wikipedia.org/wiki/Semantic_Web wikipedia.org/wiki/Namespace wikipedia.org/wiki/Web_Ontology_Language
  27. Slide 30: microformats.org
  28. Slide 31: bioformats.org
  29. Slide 32: slideshare.net/mza