The document summarizes the opportunities for conducting clinical trials related to bone and joint health supplements in India. It notes that India has a large population suffering from joint issues like osteoarthritis, with costs for trials being 20-40% lower than in Western countries. India offers a genetically diverse population as well as world-class research facilities and experienced doctors to conduct rigorous efficacy and safety trials at lower costs than other regions.
Most Affordable Knee Replacement by one the most successful Orthopedic doctor...
Claim substantiation for bone & joint health products
2. The global bone and joint health supplement
market will exceed $9 billion by 2017
The existing bone and joint health
supplement market in India is around Rs. 150
crore
3. 15 million people in the age group of 35 – 55 suffer from Knee
Osteoarthritis in the country
India has the second largest knee-osteoarthritis patient base
around the world
India is likely to notice an endemic of osteoarthritis with
about 80% of the 65+ population in the country suffering
with wear and tear of joints
40% of these people are likely to suffer from severe
osteoarthritis, which will disable them from daily activities
4. India offers cost savings of 20 – 40% as compared to the US /
Western Europe
Investigator and site fees are 30% of those in the West
Academic and Non-Academic sites for Adult and Geriatric
population
700,000 specialty hospital beds, 221 medical colleges and
skilled English-speaking medical personnel
Lower costs for domestic travel & courier services
Lower fees for translation, clinical trial supply
management, medical writing, statistical analysis and data
management
Genetically diverse population
Volunteers who have not been exposed to many medications
5. Indian population with Joint Health concerns have;
Nutritional bone disease - 52%
Endemic skeletal fluorosis - 43%
Metabolic bone disease - 5%
Bone disease rare, mixed or unidentified - 0.19%
7. Product safety profile ascertained at Certified and Accredited
facilities
International Efficacy Measurement: VAS score, WOMAC, SF
– 36, KOOS and other tests for physical function
Advanced Efficacy Diagnostic Tests: Digital X- Rays, DEXA,
MRI (cartilage), Arthroscopy
COST IN USA ($) COST IN INDIA COST SAVING
($) %
Knee MRI 500 - 800 110- 130 78% - 84 %
Digital Knee XRAY 200 25 87%
Serum Vitamin D 3 250 21 91%
Testing
Bone Mineral 217 54 75%
Density (DXA Scan)
9. The Key Opinion Leaders for Joint Health Trials at Vedic are qualified
medical professionals with an interest in scientific research which
extends beyond the realm of commercial interest.
Dr. Karne Dr. Naik Dr. Kasodekar
Qualification MS Ortho MS Ortho MS, DNB Ortho
Experience 28 yrs 34 yrs 12 yrs
CT Exp 12 yrs 8 yrs 8 yrs
Additional interests Accidents and Trauma Medical problems of Sports medicine,
Management, yogic exercises geriatrics, osteoarthritis/ pediatric orthopedics
in degenerative disorders of osteoporosis in
knee and spine menopausal women
Orthopedic Facility Own Own Associated with various
renowned hospitals
10. Robust claim substantiation for bone density / calcification,
joint mobility, joint pain and cartilage regeneration
Faster approval from local ethics committees
Experience of conducting 11 studies in 600+ volunteers
across 40 sites for U.S, Canadian and South East Asian clients
Clinical Research Papers published in international peer
reviewed journals