This is a lecture on the Basic information on Parkinson's Disease. There is also a Video that I have prepared based on this presentation on You Tube Channel - KNOLEAD
www.knolead.com
2. Why do we need to
understand About
Parkinson’s Disease
WHO Global Estimates : More than 8.5 million people worldwide are
living with PD.
The Prevalence of PD has doubled
in the past 25 years
3. Elderly Indians has increased from 5.6% (51 million) in 1961 to
7.1% (71million) in 2001.
0.
2.
4.
6.
8.
1961 2001
4. Parkinson’s disease is the commonest
movement disorder ( 24 % )
24%
76%
3-8 % of Neurological disorders
• 20 % of neurology admissions
• 33 % of residents of old age
home
Movement Disorders
5. Affects Quality of Life of Patients and Care givers
Informal carers (i.e. most commonly family members and
friends) spend many hours daily providing care for people
living with PD. This can be overwhelming. Physical, emotional
and financial pressures can cause great stress to families and
carers, and support is required from the health, social,
financial and legal systems.
15. PD and PD Plus
❖ Not All patient who are Slow are Parkinson’s Disease
❖ MIMICS of PD : PD Plus syndromes
❖ Progressive Supranuclear Palsy
❖ Secondary Parkinsonism
❖ Multi System Atrophy
❖ Cortico Basal Ganglionic Degeneration
❖ Essential Tremors
❖ Other Diseases where there might be confusion : Depression /
Balance disorders / Arthritis / Hypothyroidism
16. Myths
❖ Genetic Myths - Parkinson’s Disease is heritable - only 4 % of
PD patients are familial
❖ All tremors are PD
❖ No tt for PD
❖ Terminal illness
❖ PD patients should stop working
❖ PD patients can not live independently
❖ PD Patients can not live productive life
17. Myths
❖ PD patient has memory loss
❖ Treating doctors can predict the future
❖ Relationship with other diseases : If Person has PD
explains every other symptoms
❖ PD is not responsible for every problem
18. Points to be noted
❖ PD can not be permanently cured
❖ Management should be started as soon as possible
❖ Dopamine cannot improve all the symptoms
❖ Levodopa Phobia should be avoided - It is a tool for us
- ? should be delayed / dangerous / damages brain
❖ Levo Dopa - only works for few years ?
19. Do not get trapped !
❖ Should defer next dose of LD
❖ Stem cell - no definitive evidence
❖ Apomorphine video - faster action / but injectable /
expensive
❖ Physiotherapy / Physical activity - should always be
done
20. Myths about Sx
❖ DBS - cure / Dangerous
❖ Misinformation
❖ Creating awareness about the PD
❖ Education patient/ care givers / Employers need to be
Educated About PD
❖ Team Work Should be emphasised
22. PD symptoms
❖ Complex
❖ Variale
❖ Pattern / phenomenology
❖ Diagnosis may need review after sometime
23. Akinesia /Bradykinesia
❖ Amplitude and speed
❖ Progressive reduction in the amplitude and speed at different joints
❖ 64 movement or repetitions
❖ micrographia
❖ D/D :
❖ Depression - hypomimia ;
❖ Dystonia may lead to decreased arm swing
❖ Gait problems - also seen in arthritis
24. Tremors
❖ Resting / pill rolling / Remergent termors
❖ D/D : Essential tremors - make a spiral
❖ Drug induced tremors - Hyperthyroid / Beta Agonists -
Asthma Medicines
25. Subtypes of Parkinson’s
Disease
❖ Tremor Predominant
❖ Postural Instability Gait Disorder
❖ PDD - Parkinson’s Disease with Dementia
❖ PD with prominent Non Motor Symptoms
27. Red Flags
❖ Rapid Progression to wheel chair in 5 yr
❖ Early autonomic failure in 5
❖ Early bulbar function in 5 yr
❖ Symm parkinsonism
❖ Absence of non motor symptoms
❖ Pyramidal signs
❖ Early and Reccurent falls
❖ Retrocollis - Trunk bent backwards
29. Management
❖ Non Pharmacological
❖ Pharmacological : Medicines that work on Dopamine
Pathway
❖ Surgery - DBS - Deep Brain Stimulation
❖ Stem Cell/ Gene Therapy - not an option as of now
30. Take Aways
❖ Learn to look for Symptoms of Parkinson’s Disease
around you
❖ Send the patient to a Neurologist so that Diagnosis is
confirmed
❖ Management should be started as soon as possible
❖ Surgery is option is selected cases
❖ Physical Activity should be emphasised in all cases
31. It is Your Life !
&
You need to make sure,
You live it to the full…