Report Scope & Objectives -------------------------- Life science research is weathering an economically challenging time, exacerbated by the federal budget sequestration in the United States and by continued austerity in Europe. Grant money from all sources, both public and private, is increasingly difficult to obtain; and pharmaceutical spending on R&D has flattened following years of solid gains. Adds to this mix a decreased level of reimbursement for molecular diagnostic testing and a slow recovery from the "Great Recession" to establish the external macro economic environment that has led to a new normal that is defined by increasingly constrained budgets. By contrast, developing nations in Asia (China in particular) are making significant investments in higher education, with a focus on science and technology, to include biotechnology. In addition, many global pharmaceutical and biopharmaceutical firms are establishing research centers in these countries; taking advantage of lower cost structures and the new availability of a well-trained work force. Our 2013 studies suggest that average laboratory budgets in Asia are larger than those in the United States and Europe. In this complex macroeconomic environment, life science suppliers are seeking guidance as to how to anticipate market trends in the United States, Europe and Asia in 2014. In this multi-sponsor report, BioInformatics LLC has conducted an in-depth exploration of projected lab budgets and sources of funding by region, and the implications of these findings for the life science tools market in the coming year. The objective of this study is to assess sources of funding, the competitive landscape and market opportunities for life science tools companies. From the perspective of end-users, the goals of this assignment will be to: -Understand current sources of funding from government/stimulus/private foundation grants, distribution time frame and how labs initiate applications for funding. -Compare and contrast FY2013 (actual), and FY2014 (projected) average lab budgets in total by broad product category, region and market segment; providing directional information for FY2014. -Estimate scientists' budget for purchases and anticipated purchases in instrumentation and consumables, examining trends across key product categories. -Assess how optimistic scientists are regarding funding and the future of life science research. To purchase this report, please contact: Angela Fernandez Marketing/Sales Coordinator BioInformatics LLC 703.778.3080 ext. 14 reports@gene2drug.com www.gene2drug.com

1. gene2drug.com
Life Science Industry Market
Research

2. About this Report
• Get an overview of the economic landscape that
frames the report
• Learn about the scope of this report and how it will
help you with 2014 planning
2
gene2drug.com
Life Science Industry Market
Research

3. About BioInformatics LLC
 A full-service market research
firm since 1994:
• Published and syndicated
reports
• Consulting and strategy
development
•
•
•
•
3
Expert interviews
Focus groups
Surveys
RateMyProduct™
gene2drug.com
Life Science Industry Market
Research

4. About BioInformatics LLC
 Conducting market
research exclusively on
scientific markets:
manufacturing & material science
environmental testing
clinical diagnostics
• Lab products
• Analytical
instrumentation
• Biotechnology research
laboratory products
chemical, food & beverage
& bioprocessing
• Drug discovery &
life sciences
development
pharmaceutical
4
agriculture biotech
gene2drug.com
• Molecular diagnostics
Life Science Industry Market
Research

5. About BioInformatics LLC
Project team includes scientists,
statisticians and business analysts.
Instant access to a 74,000+
member expert scientific panel.
Question 9*
What are your MAJOR area(s) of interest with respect to your epigenetics research?
(check all that apply)
Respondents
200
Gene regulation
135
Disease mechanisms
115
Biomarkers
110
Basic biology of epigenetics
94
Therapeutic targets
41
Genomic imprinting
57%
46
Stem cells
68%
Gene regulation
Disease mechanisms
27
55%
Biomarkers
47%
Basic biology of epigenetics
Transgenerational epigenetic
inheritance
21
Tissue repair/regeneration
20
X chromosome inactivation
10
23%
Therapeutic targets
Stem cells
Conduct market research for major
suppliers in the industry.
20%
14%
Genomic imprinting
Transgenerational epigenetic
inheritance
10%
Tissue repair/regeneration
10%
5%
X chromosome inactivation
0%
10%
20%
30%
40%
50%
60%
70%
80%
* Totals are based on number of times an item was selected.
* Percentages are based on number of respondents.
An Overview of Your Epigenetic Research
© 2009 BioInformatics, LLC
5
www.gene2drug.com
3-17
gene2drug.com
Life Science Industry Market
Research

6. Report Author & Lead Analyst
Robin Rothrock, Ph.D.
Director of Publications
6
gene2drug.com
Life Science Industry Market
Research

7. Overview of the
Economic Landscape
7
gene2drug.com
Life Science Industry Market
Research

8. 8
gene2drug.com
Life Science Industry Market
Research

9. United States
 Sequester
 Uncertainty regarding
healthcare reform
 Changes in molecular
diagnostic tests coding and
reimbursement
 Flat to declining
pharmaceutical R&D
budgets
9
gene2drug.com
Life Science Industry Market
Research

10. Europe
 Continued fiscal austerity
 Changes in healthcare
institutions and funding
 Funding of research is
complex and multilayered
 Cross-border collaboration is
increasing
 Leading institutions are taking
action to be competitive with
the U.S. in recruiting postdocs
from India and China
10
gene2drug.com
Life Science Industry Market
Research

11. China
 Government and
commercial investment:
>$260 billion over the next 5
years
• 500 universities
• More than 150,000 life science
graduates per year
• Four innovation clusters
• 7,500 life science companies
• 200 life science incubators
• 100 life science parks
11
 “Sea turtles” return
 Growth in pharmaceutical
market
gene2drug.com
Life Science Industry Market
Research

12. A New Normal for Life Science Research
 Slow global recovery
 Unfavorable research funding
  pricing pressure
 Growth in Asian markets may be slowing
12
gene2drug.com
Life Science Industry Market
Research

13. Report Scope
13
gene2drug.com
Life Science Industry Market
Research

14. Objectives
 Understand current sources of funding
 Compare and contrast FY2013 (actual), and FY2014
(projected) average lab budgets
 Estimate scientists’ budget for purchases and anticipated
purchases in instrumentation and consumables
 Take the pulse of the life science community regarding
funding and the future of life science research
14
gene2drug.com
Life Science Industry Market
Research

15. Framework
Secondary research
Primary research
 An extensive review of
 Quantitative survey
 United States and Europe
 Have budget authority
relevant research councils,
funding agencies and private
funding sources
administered to life scientists
in the United States, Europe
and Asia
 Sample size ≅ 1,000
 75% academic/gov’t and
25% life science industry
15
gene2drug.com
Life Science Industry Market
Research

16. Questionnaire
 Funding & Budgets
 Techniques
• Current sources of funding
• Average lab budgets (2013 and
2014)
• Average lab budgets for
instrumentation
• Average lab budgets for
consumables
• Percent budget allocation for
overhead and salaries
• Current usage
• Explore adoption of new
products/techniques in the next
12 months
• Purchase of instrumentation
(actual in 2013 and expected in
2014)
• Identify new and emerging
technologies
• Laboratory headcount
16
gene2drug.com
Life Science Industry Market
Research

17. Customer Sentiment
Will my project
be funded
next year?
17
gene2drug.com
Life Science Industry Market
Research

18. Product Categories
 Instrumentation for…
 Consumables
• Cell-based analysis (flow cytometers,
high content analyzers, all
microscopes, high throughput
screening and analysis systems, etc.)
• Genome analysis (thermal cyclers,
real-time PCR instrumentation,
microarray instrumentation, NGS,
capillary electrophoresis, etc.)
• Protein analysis (chromatography,
electrophoresis, mass spectrometry,
label-free detection, calorimetry,
NMR, CD, etc.)
• Cell-based analysis kits and reagents
(cell culture media and reagents,
antibodies, cell biology kits, etc.)
• Genome analysis kits and reagents
(enzymes, kits, ladders, nucleic acid
purification and separation products,
oligonucleotides [primers, RNAi], etc.)
• Protein purification and separation
kits and reagents (chromatography
media, electrophoresis matrices,
protein ladders, etc.)
• General laboratory chemicals,
plasticware, glassware and
disposables
18
gene2drug.com
Life Science Industry Market
Research

19. Cell-Based Techniques
 Bacteria Culture
 Cell-Based Assays
 Confocal Microscopy
 Eukaryotic Cell/Tissue Culture
 Flow Cytometry
 Fluorescence Microscopy
 Gene Expression Analysis
 High Content Screening
 High-Throughput Screening
(HTS)
 Immunohistochemistry
 Light Microscopy
 Stem Cell Culture/Analysis
19
gene2drug.com
Life Science Industry Market
Research

20. Genomics Techniques
 Classical End-Point PCR
 Cloning/Molecular biology
Techniques
 DNA/RNA Microarrays
 Genotyping
 Next Generation Sequencing
 Real-Time PCR
 RNAi (including siRNA, miRNA)
 Sanger DNA Sequencing
 Single Nucleotide Polymorphism
20
gene2drug.com
Life Science Industry Market
Research

21. Protein Techniques
 2-D Gel Electrophoresis
 Calorimetry (including ITC, DSC)
 Enzyme-linked Immunosorbent







21
Assay (ELISA)
Label-Free Detection/Analysis
(Including Biosensors, SPR, etc.)
Light Scattering (MALS, DLS)
Mass Spectrometry
Multiplex Bead Assays
Protein Purification & Separation
Protein Structural Analysis (NMR,
CD, etc.)
Western Blotting
gene2drug.com
Life Science Industry Market
Research

22. Deliverable
22
gene2drug.com
Life Science Industry Market
Research

23. Why this report?
23
gene2drug.com
Life Science Industry Market
Research

24. Share Gain/Share Protect Strategies
 Where is the growth?
 Funding trends?
 Are researchers pitching their
grants to follow the money?
24
gene2drug.com
Life Science Industry Market
Research

25. How You Can Use It
 Check assumptions
 Make decisions
 Forecast revenues
 Identify potential growth
25
gene2drug.com
Life Science Industry Market
Research

26. Pricing
Cost of non-sponsor report
purchase is $18,000
Deliverables Include:
• Electronic PDF of Report
• Data Set in XLS Format
• Data Legend
26
gene2drug.com
Life Science Industry Market
Research

27. Questions?
27
gene2drug.com
Life Science Industry Market
Research

28. Contact
Lab Budgets and
Sources of Funding in
2014
December 2013
Robin Rothrock, Ph.D.
Director of Publications
703.778.3080 x25
r.rothrock@gene2drug.com
CALL TODAY to GET YOUR COPY OF
THE REPORT!
Angela Fernandez
Marketing Coordinator
703.778.3080 x14
a.fernandez@gene2drug.com
28
gene2drug.com
Life Science Industry Market
Research