This document describes a quality improvement initiative to provide education to PACU nurses on caring for patients with congenital heart defects. A case of desaturation in a post-operative cardiac patient prompted an assessment of nurse knowledge which found gaps. Educational interventions including lectures, simulations, reference cards and bedside teaching were provided. Follow-up surveys found improvement in nurses' perceived knowledge of congenital defects and comfort caring for cardiac patients. Ongoing education is needed due to staff turnover in the non-dedicated cardiac PACU. The multimodal approach improved nurse confidence for better patient outcomes.