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Natural selection Genetic Drift
Evolutionary forces involved in speciation
Forms of organisms in a population that are best
adapted to the environment increases in frequency
over a number of generations
Random change in allele frequency as a result of
chance from one gen to next in a finite
population
Causes fixation of alleles
(0= lost 1=fixed- drift halts)
Positive selection(↑fitness ↑frequency in population),
Negative selection(↓fitness), Balancing
selection(advantages only in heterozygous conditions-
maintained)
Operates non-randomly Operates randomly
Non-directional
Guided only by chance
Directional
Guides evolution in a direction that increases
survival & reproductive fitness
Favours spread of alleles whose phenotypic
effects increases fitness and survival
Acts upon the genotypic features within a
population irrespective of their phenotypic effect
Impact of genetic drift
Bottleneck effect
● Population drastically reduces to a
significantly smaller size over a
short period of time
2
✗ Reasons- Disaster, hunting,
habitat destruction etc
✗ Genetic diversity↓
✗ Loss of alleles → Higher genetic
drift
✗ Thus, new population genetically
distinct from original
Founder effect
● New population develops by a few
members of original large population
✗ Reduced genetic variation from
original
✗ Variation depends upon the number
of founder members
5
MODES OF NATURAL SELECTION
DIRECTIONAL
Stabilizing
Disruptive
Individuals at one end of the
frequency distribution are selected
Due to change in environment
Favours extreme phenotype
Favours accumulation of mutations
that increases fitness in changing env
6
MODES OF NATURAL SELECTION
Stabilizing
Individuals at both the ends are
eliminated
Constant or unchanging environment
Favors average/ normal phenotypes
Checks on accumulation & introduces
homozygosity
7
MODES OF NATURAL SELECTION
Disruptive
Divergent selection pressures in
different parts of its distribution area
Individuals are both extremes are
favoured
Favours both extremes
Directional Selection Stabilizing selection Disruptive selection
Individuals at one end of the
frequency distribution are
selected
Individuals at both the ends
are eliminated
Individuals are both extremes
are favoured
Due to change in environment Constant or unchanging
environment
When population is subjected
to divergent selection
pressures in different parts of
its distribution area
Favours extreme phenotype Favors average/ normal
phenotypes
Favours both extremes
Favours accumulation of
mutations that increases
fitness in changing env
Checks on accumulation &
introduces homozygosity
9
Antibiotic resistance among bacteria represents?
a. Balancing
b. Stabilizing
c. Directional
d. Disruptive
10
Self cross between Aa results in AA, Aa,aa F1 progeny, the forces of
evolution preserving either AA or aa is:
a. Stabilizing selection
b. Cyclic
c. disruptive
d. directional
Selection which operates against any direction & do not allow to
disrupt the present mean is termed?
a. Directional
b. Stabilizing
c. Disruptive
d. Balancing
11
A person heterozygous for sickle cell anemia has
advantage for both malaria & sickle cell anemia it
illustrates?
disruptive
a. Directional selection
b. Heterozygote advantage
c. Disruptive selection
d. Directed mutation selection

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Evolution- Natural selection and Genetic Drift and modes of natural selection

  • 1. 1 Natural selection Genetic Drift Evolutionary forces involved in speciation Forms of organisms in a population that are best adapted to the environment increases in frequency over a number of generations Random change in allele frequency as a result of chance from one gen to next in a finite population Causes fixation of alleles (0= lost 1=fixed- drift halts) Positive selection(↑fitness ↑frequency in population), Negative selection(↓fitness), Balancing selection(advantages only in heterozygous conditions- maintained) Operates non-randomly Operates randomly Non-directional Guided only by chance Directional Guides evolution in a direction that increases survival & reproductive fitness Favours spread of alleles whose phenotypic effects increases fitness and survival Acts upon the genotypic features within a population irrespective of their phenotypic effect
  • 2. Impact of genetic drift Bottleneck effect ● Population drastically reduces to a significantly smaller size over a short period of time 2 ✗ Reasons- Disaster, hunting, habitat destruction etc ✗ Genetic diversity↓ ✗ Loss of alleles → Higher genetic drift ✗ Thus, new population genetically distinct from original
  • 3. Founder effect ● New population develops by a few members of original large population ✗ Reduced genetic variation from original ✗ Variation depends upon the number of founder members
  • 4.
  • 5. 5 MODES OF NATURAL SELECTION DIRECTIONAL Stabilizing Disruptive Individuals at one end of the frequency distribution are selected Due to change in environment Favours extreme phenotype Favours accumulation of mutations that increases fitness in changing env
  • 6. 6 MODES OF NATURAL SELECTION Stabilizing Individuals at both the ends are eliminated Constant or unchanging environment Favors average/ normal phenotypes Checks on accumulation & introduces homozygosity
  • 7. 7 MODES OF NATURAL SELECTION Disruptive Divergent selection pressures in different parts of its distribution area Individuals are both extremes are favoured Favours both extremes
  • 8. Directional Selection Stabilizing selection Disruptive selection Individuals at one end of the frequency distribution are selected Individuals at both the ends are eliminated Individuals are both extremes are favoured Due to change in environment Constant or unchanging environment When population is subjected to divergent selection pressures in different parts of its distribution area Favours extreme phenotype Favors average/ normal phenotypes Favours both extremes Favours accumulation of mutations that increases fitness in changing env Checks on accumulation & introduces homozygosity
  • 9. 9 Antibiotic resistance among bacteria represents? a. Balancing b. Stabilizing c. Directional d. Disruptive
  • 10. 10 Self cross between Aa results in AA, Aa,aa F1 progeny, the forces of evolution preserving either AA or aa is: a. Stabilizing selection b. Cyclic c. disruptive d. directional Selection which operates against any direction & do not allow to disrupt the present mean is termed? a. Directional b. Stabilizing c. Disruptive d. Balancing
  • 11. 11 A person heterozygous for sickle cell anemia has advantage for both malaria & sickle cell anemia it illustrates? disruptive a. Directional selection b. Heterozygote advantage c. Disruptive selection d. Directed mutation selection