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Bioinformaticians to the rescue
Elena Sügis
elena.sugis@.ut.ee
Have you ever thought of
making the world a better
place with computer science?
http://www.scifiwright.com/2015/06/tomorrowland/
Slide credit: D.Fishman, Introduction to ML in bioinformatics
Bioinformatics
How we do science
lots of
experiments
v
analysis
Science
knowledge
hypothesis
v
v
The Wellcome Human Genome Library in London (Left CC: Russ London, Right Source: Wellcome Collection)
What’s in the bookcase?
The Wellcome Human Genome Library in London (Left CC: Russ London, Right Source: Wellcome Collection)
A single
human genome
~3GB
Big Data
ATGCTCGTAC = 1mm
Tallinn - Jõgeva - Misso:
320 km
Slide image credit: P.Adler. Bioinformaatika, põnev väljakutse
Labs that produce data
Research groups that can
analyse data
Labs that produce data
Experts to analyse data
Motivation
Labs that produce data
Experts to analyse data
Motivation
Labs that produce data
Research groups that can
analyse data
YOU?
Because Excel can’t help anymore
What kind of problems can we solve
using bioinformatics?
Finding the right treatment
Illustration by Zhou Tao (ShanghaiDaily.com)
VS
ACCTTGCTTACC
Medical records
Slide image credit: D.Fishman, ML in bioinformatics
ACCTTGCTTACC
Medical records
How does The Perfect
Bioinformatician look like?
Computer
Science
Computer
Science
Biology
Computer
Science
Biology
Statistics
Computer
Science
Biology
Statistics
Bioinformatics is a broad field
Proteomics
Black magic
Machine learning
Modeling
Algorithms
Sequences
Perks of being a
bioinformatician
BIIT 2016BIIT 2016
MEM
Working with smart colleagues
Learning something new everyday
http://boingboing.net/2015/05/11/the-only-technique-to-learn-so.html
Travelling
You can make an impact
http://www.scifiwright.com/2015/06/tomorrowland/
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
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and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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us…
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
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EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
Genes
are
us…
and them.SOURCE:,JAVIER,HERRERO,,EUROPEAN,MOLECULAR,BIOLOGY,LABORATORY—
EUROPEAN,BIOINFORMAT,ICS,INSTITUTE
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