2. Cellular respiration is a metabolic pathway that
breaks down glucose and produces ATP. The stages of
cellular respiration include glycolysis, pyruvate
oxidation, the citric acid or Krebs cycle, and oxidative
phosphorylation.
3.
4.
5. •Cells need ATP
•ATP produced by the
mitochondria
•ATP typically created
through Cellular
respiration.
6. •Glucose (from food) is
broken down to make ATP
•3 Stages of Cellular
Respiration
•1. Glycolysis
•2. Krebs Cycle
•3. Electron transport chain
7. Glycolysis is the first of the main metabolic path-
ways of cellular respiration to produce energy in the
form of ATP. Through two distinct phases, the six-
carbon ring of glucose is cleaved into two
threecarbon sugars of pyruvate through a series of
enzymatic reactions.
⮲Location: Cytoplasm
⮲Event: Glucose is broken down by ATP, NAD+, and
various enzymes
11. Glycolysis produces 2 ATP, 2 NADH, and 2
pyruvate molecules: Glycolysis, or the aerobic
catabolic breakdown of glucose, produces energy in
the form of ATP, NADH, and pyruvate, which itself
enters the citric acid cycle to produce more energy.
13. Pyruvate oxidation or Pyruvate decarboxylation,
also known as the link reaction (or oxidative
decarboxylation of pyruvate), is the conversion of
pyruvate into acetyl-CoA by the enzyme complex
pyruvate dehydrogenase complex.
14.
15. If we consider the two pyruvates that enter from
glycolysis (for each glucose molecule), we can
summarize pyruvate oxidation as follows:
⮲Two molecules of pyruvate are converted into two
molecules of acetyl CoA.
⮲Two carbons are released as carbon dioxide
⮲2 NADH are generated from NAD+
16. Krebs cycle catalyzed by enzymes in which the
pyruvate derived from nutrients and converted to
Acetyl Coenzyme A is completely oxidized and
broken down into carbon dioxide and water to
produce high-energy phosphate compounds, which
are the source of cellular energy.
Location: mitochondrial matrix
17.
18.
19.
20.
21.
22.
23. In a single turn of the Krebs cycle,
⮲two carbons enter from acetyl CoA, and two
molecules of carbon dioxide are released;
⮲three molecules of NADH and one molecule of
FADH2 and;
⮲one molecule of ATP or GTP is produced.
24. e- e-
e-
e- e-
e-
1. NADH and FADH2 deliver H+
AND e-
2. Electrons activate protein
channels to pump H+ ions out of the
matrix.
25. matrix.
H H
H
e- e-
e-
e- e-
e-
H
P
A P P
3. H+ activate ATP synthase
- H+ ions diffuse through ATP
synthase
- ADP + Pi bond to create ATP]
- Up to 34 ATPs created
26. 4. Water waste created when O, H,
e- bond together
H
H
e- e-
e-
e- e-
e-
H
P
A P P
P
A P P
H
27. e- e-
e-
e- e-
e-
1. NADH and FADH2 deliver H+ AND e-
2. Electrons activate protein channels
to pump H+ ions out of the matrix.
28. H H
H
e- e-
e-
e- e-
e-
H
P
A P P
3. H+ activate ATP synthase
- H+ ions diffuse through ATP synthase
- ADP + Pi bond to create ATP]
- Up to 34 ATPs created
29. 4. Water waste created when O, H, e-
bond together
H
H
e- e-
e-
e- e-
e-
H
P
A P P
P
A P P
H
30.
31.
32. Theoretical yield is what you calculate the yield
will be using the balanced chemical reaction. Actual
yield is what you actually get in a chemical reaction.
33. `
•Glucose (from food) is
broken down to make ATP
•3 Stages of Cellular
Respiration
•1. Glycolysis
•2. Krebs Cycle
•3. Electron transport chain