There is an increasing availability of free and open access resources for scientists to use on the internet. Coupled with the increasing availability of Open Source software tools we are in the middle of a revolution in data availability and tools to manipulate these data. ChemSpider is a free access website for chemists built with the intention of providing a structure centric community for chemists. As an aggregator of chemistry related information from many sources, at present over 21.5 million unique chemical entities from over 200 separate data sources, ChemSpider has taken on the task of both robotically and manually curating publicly available data sources. This presentation will provide an overview of the ChemSpider platform and how it is fast becoming the centralized hub for resourcing information about chemical entities.

1. Navigating the Complex Web of Chemistry Using ChemSpider

2. Antony Williams vs Identifiers Old Passport ID Dad, Tony, others SSN Green Card License 5 email addresses ChemSpiderman (blog, Twitter account, Facebook, Friendfeed) OpenID … .

3. Aspirin vs Chemical Identifiers

5. Linked Data Cloud

9. The Final Search Strategy

10. All Those Names, One Structure

13. The InChI Identifier

14. Multiple Layers

15. InChIStrings Hash to InChIKeys

16. Oleoylethanolamine

17. InChIKey Searches Work

18. Search Engine Dependencies

19. Search Engine Dependencies

20. InChIs have traction…

21. RDF Linking of Structures

22. PubChem

23. The Simplest Organic Molecule

24. Question Everything online: www.dhmo.org

25. The Structure-Based Data Cloud

26. Vancomycin

29. Vancomycin on ChemSpider

30. Vancomycin

31. Vancomycin Search Molecular SKELETON Search Full Molecule

32. Full Skeleton Search: 104 Hits

33. Full Molecule Search: 4 Hits

38. Search Cholesterol

39. Search Cholesterol

40. Search Cholesterol

41. Search Cholesterol

42. Linked across the internet

43. Kyoto Encyclopedia of Genes and Genomes

44. Links to Patents based on structure

47. Complex Data and Information

48. Remember – QUALITY ISSUES

49. The FDA’s DailyMed

50. Incorrect Structures

52. Crowd-sourcing Chemistry Curation

53. We Need Recognition and Rewards

54. Master Curators, Curators, Depositors

56. Blogs need InChIs too!

57. Blogs need InChIs too!

58. Use Intelligent Structures : ChemSpider Embed Web Service

59. ChemSpider Web Services

61. Nature Chemistry Compound Pages

62. Project Prospect

63. ChemMantis

64. Deposit Structures

65. Species – linked to Wikipedia

67. The InChI “Resolver”

68. InChI Resolver to DOIs Structure Search the Web

71. [email_address] Twitter: ChemSpiderman www.chemspider.com/blog